nandakumar wrote: Amber G. wrote:
From this arXiv: Vaccinated individuals can be infected with B.1.617, but without severe disease
. The data go some way to explaining the dominance of this variant in a partially immune population, but highlight that vaccination is still protective for the majority of people.https://www.biorxiv.org/content/10.1101/2021.05.08.443253v1
>>> First molecular insights into B.1.617 VOC by collaboration of INSACOG and Gupta Lab.
Only moderate antibody resistance but greater syncytium formation. Overall fits higher transmissibility, ?symptoms, but low severity in vaccinated.
I am hearing stories from people in the friends circle and extended family that they contracted Covid infections despite having had two shots of vaccine. Granted that vaccination is not proof against infection the interesting thing is such instances have come predominantly from those who have had Covishield. This was confirmed by a doctor relative of mine. I wonder if there are exhaustive data on infection among vaccinated individuals and the distribution between the two vaccines currently available.
Don't know about "exhaustive" part (
) but of course there is lot of data which is being studied (and unfortunately people are putting "spin" and sometimes outright silly "analysis" in media). From what I have seen the data / or analysis by people who I respect the bottom line is Vaccines are extremely effective
specially for saving a trip to hospital or death. The data (for academic purpose) for different vaccines may be "interesting" but it is clear that both in USA and India - *all* vaccines have been very effective. My take (from the verified data and analysis) :
- If you have taken only one shot and two weeks have passed - Probability for testing positive (or showing symptoms) is about 50% lower.
(Pfizer and Moderna numbers may be a little higher but practically irrelevant)
- Two/three weeks after the all doses ( 65- 95%) less probability that you will catch a virus vs non-vaccinated individual.
(Again - we are comparing oranges with oranges - *vaccine* is *not* the only factor - sometimes ignored in anecdotal evidences - A person with vaccine may be in higher probability if he is out without a mask or his immune system is compromised, or run into B117 type virus in comparison to a healthy person who is in quarantine )
What is encouraging is the morbidity (or serious illness) data - among fully vaccinated individuals (Both here in USA or in India) it is very small (deaths verified due to infection only) - Numbers I have seen is something like (.02% for morbidity and single digit for serious illness). Fortunately this is true also for variants which are in India/USA.
This is true for all the vaccines (Covidshield, Covaxin, Pfizer, Moderna, J&J) -- More data for some, little less data/confidence for others but bottom line they are extremely encouraging.
(Disclaimer - The above is my take based upon what I have read - take it for what ever it's worth)