Wuhan Coronavirus Resource Thread

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Vayutuvan
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Re: Wuhan Coronavirus Resource Thread

Post by Vayutuvan »

UlanBatori wrote:Hmmm! UBCN tried reading those and gave up. Sounds like these Modern Viruses (virii?) all speak computer languages and have Andromeda_X Operating Systems.
rather Plan 9 (from Outer Space) Distributed OS. Just for reference, Bell Labs was developing a Distributed OS called Plan 9 whose name is taken from an SF cult classic movie titled Plan 9 from Outer Space

I have a technical question - how long does it take to sequence a virus? How long are the amino acid molecules? (is that the right question at all?)
John
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Re: Wuhan Coronavirus Resource Thread

Post by John »

Vayutuvan wrote:
John wrote: Before we are all start acting arm chair medical experts ...
I thought there are several practicing medical experts on BRF (including @sanjaykumar ji).
Should have said Virologist not medical expert don’t think we have any, if so would like to get their opinion on Coronavirus.
UlanBatori
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Re: Wuhan Coronavirus Resource Thread

Post by UlanBatori »

Why is it that we don't hear of these massive virus outbreaks in say, South America (Heaven forbid!) Rio de Janeiro and Mexico City match Wuhan and Shanghai in crowding and pollution and are probably far worse in sanitation, food hygeine and also sex habits, come to think of it.

China has a long list of these now. But none from South Am. Nor from Pakistan :((
chanakyaa
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Re: Wuhan Coronavirus Resource Thread

Post by chanakyaa »

Some numbers for context...

Disease Burden of Influenza (CDC)
Each year CDC estimates the burden of influenza in the U.S. CDC estimates that influenza has resulted in between 9 million – 45 million illnesses, between 140,000 – 810,000 hospitalizations and between 12,000 – 61,000 deaths annually since 2010...
Out of curiosity, I ran a quick search in Elsevier for Coronavirus. The study on the topic goes back to 1980s. I'm sure there are other resources with deep repositories of research. We can talk about DNA, sequencing, and proteins, but, how much do we really understand this extremely complex subject to confidently accept theories peddled by alleged experts?
coronavirus infection
CalvinH
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Re: Wuhan Coronavirus Resource Thread

Post by CalvinH »

UlanBatori wrote:Why is it that we don't hear of these massive virus outbreaks in say, South America (Heaven forbid!) Rio de Janeiro and Mexico City match Wuhan and Shanghai in crowding and pollution and are probably far worse in sanitation, food hygeine and also sex habits, come to think of it.

China has a long list of these now. But none from South Am. Nor from Pakistan :((
May be because of Chinese diet preferences that increases the chances of extended exposure of virus carrying wild animals with humans. Viruses that mutate in wild and would have died with their carriers are bought to markets and co-mingled with other produce and exposed to humans for extended duration (transporting, storage and selling).
Last edited by CalvinH on 04 Feb 2020 08:17, edited 1 time in total.
CalvinH
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Re: Wuhan Coronavirus Resource Thread

Post by CalvinH »

Deleted-duplicate
John
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Re: Wuhan Coronavirus Resource Thread

Post by John »

CalvinH wrote:
UlanBatori wrote:Why is it that we don't hear of these massive virus outbreaks in say, South America (Heaven forbid!) Rio de Janeiro and Mexico City match Wuhan and Shanghai in crowding and pollution and are probably far worse in sanitation, food hygeine and also sex habits, come to think of it.

China has a long list of these now. But none from South Am. Nor from Pakistan :((
May be because of Chinese diet preferences that increases the chances of extended exposure of virus carrying wild animals with humans. Viruses that mutate in wild and would have died with their carriers are bought to markets and co-mingled with other produce and exposed to humans for extended duration (transporting, storage and selling).
Yeap I touched on that in post few hrs ago and let’s not forget the Chinese officials turn a blind eye (aka bribed) to safety and health violations. This market had numerous violations and it operated right next to main Government building.

All this is because Everything Chinese party does is purely for a show while the officials pocket all $$ and build nice condos in Toronto or NY. Even these hospitals they are cranking out it is all for a show they plenty of unoccupied apartments, hotels or office building which could have been used to house all the influx of patients.
Last edited by John on 04 Feb 2020 08:30, edited 1 time in total.
g.sarkar
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Re: Wuhan Coronavirus Resource Thread

Post by g.sarkar »

https://news.rediff.com/commentary/2020 ... 87fb13d651
China suspends work on aircraft carrier, jets
February 04, 2020
Chinese armament firms, including those building aircraft carrier and military aircraft, have halted work in order to focus on controlling the risk of rapidly spreading coronavirus that has killed 361 people in the country, official media here reported on Monday. The deadly virus, which so far infected 17,341 people in China, has spread to 25 countries, including India, the United States, the United Kingdom and Russia.
"Chinese armaments companies have postponed planned work in order to concentrate on controlling the risk of spreading the novel coronavirus, including those building the country's new aircraft carrier and fighter jets," state-run Global Times said in a brief report.
.....
Gautam
Are things far worse than being reported?
John
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Re: Wuhan Coronavirus Resource Thread

Post by John »


Are things far worse than being reported?
I am betting it is to save $$$ so they can pump into economy (fudge numbers) so they can hit 5.x % GDP this year.
Arun.prabhu
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Re: Wuhan Coronavirus Resource Thread

Post by Arun.prabhu »

There are apparently 30 incinerators to burn bodies in Wuhan. They are operating at Full capacity per reports. A lot of the deaths are being documented as organ failure or pneumonia. There aren’t enough kits to test all cases and even if there were, there aren’t enough technicians or labs to do a thorough job with the tests. The ~2400 number increase everyday... the number that has plateaued and gives the appearance of spread of disease getting slowly under control? There are two dozen designated hospitals in Wuhan, each of which receive 100 kits per day. And most of the cases continue to be from Wuhan.

They don’t have the bed capacity in hospitals to admit patients. Patients are being sent home and being asked to quarantine themselves. This thing is not under control. It fact, with so many confirmed and suspected (read not serious enough to spare a kit and time and labor to confirm) cases spread throughout China Ergo, the draconian measures being implemented by China in a panic.

Best case: Chinese economy is hosed this year and Xi has eliminated enough opposition already that he manages to not slip and fall in his tub, break his neck and then accidentally shoot himself in the head followed by a dozen times in the back.

Middling case: Chinese economy is hosed this year and xi has an accident and the disease is controlled within China and has minimal impact elsewhere. Better than fifty percent possibility of revolt and chinese civil war within a decade.

Worst case: pandemic. Everyone gets hosed.
g.sarkar wrote:https://news.rediff.com/commentary/2020 ... 87fb13d651
China suspends work on aircraft carrier, jets
February 04, 2020
Chinese armament firms, including those building aircraft carrier and military aircraft, have halted work in order to focus on controlling the risk of rapidly spreading coronavirus that has killed 361 people in the country, official media here reported on Monday. The deadly virus, which so far infected 17,341 people in China, has spread to 25 countries, including India, the United States, the United Kingdom and Russia.
"Chinese armaments companies have postponed planned work in order to concentrate on controlling the risk of spreading the novel coronavirus, including those building the country's new aircraft carrier and fighter jets," state-run Global Times said in a brief report.
.....
Gautam
Are things far worse than being reported?
g.sarkar
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Re: Wuhan Coronavirus Resource Thread

Post by g.sarkar »

https://www.nytimes.com/2020/02/03/worl ... -sars.html
Beijing Sees ‘Major Test’ as Doors to China Close and Coronavirus Deaths Surpass SARS
The number of dead is likely to grow as the tally of confirmed infections surges by more than 2,000 every day. “There’s no sign that it’s getting better,” said a health expert.
By Sui-Lee Wee
Feb. 3, 2020

China’s Communist Party leadership called the month-old coronavirus epidemic a “major test” on Monday as other nations escalated efforts to isolate China, unnerving China’s stock market, depressing global oil prices and raising new anxiety about the world’s most populous country.
The growing global move to effectively cut off China’s 1.4 billion people came as government officials reported the new coronavirus strain had killed more in mainland China, 425 as of Tuesday morning, than the SARS outbreak in 2002 and 2003, confirming it as one of the deadliest epidemics in recent Chinese history.
Many leading infectious disease experts say the outbreak is likely to become a pandemic, defined as an ongoing epidemic on two or more continents, and that stringent anti-contagion restrictions may have come too late. “There’s no sign that it’s getting better,” said Leo Poon, division head of the public health laboratory sciences department at the University of Hong Kong. “We don’t see a pattern of decline, and that’s a problem.”
President Xi Jinping of China called on Monday for all officials to make reducing the number of infections and deaths a top priority.
Mr. Xi presided over a meeting of senior Communist Party leaders at which they acknowledged shortcomings in policies on public health and emergency management, according to a report by China’s official news agency. The leaders called the coronavirus epidemic “a major test of China’s system and capacity for governance.”
Xinhua quoted Mr. Xi as saying that officials who resist orders and “lack boldness” could be punished — suggesting that at least some regions in China may have balked at devoting resources and personnel to stopping the contagion.
As of Monday, China had 20,438 cases, the government said on Tuesday morning, and more than 160 cases have been diagnosed in two dozen other countries, including 11 in the United States. During the SARS outbreak, China had 349 deaths and 5,327 cases, according to the World Health Organization.
Government figures show that confirmed coronavirus infections are surging by more than 2,000 daily.
Some deaths still go unreported, and many residents in Wuhan, the epicenter of the outbreak in central Hubei Province, say they believe the true number of deaths across China may be higher than the official tally, because many of the ill have been turned away by overstretched hospitals. Several residents said they had heard of people dying at home.
The commonly accepted need for isolating suspected cases collided with anger, confusion and recrimination between China and other governments.
In the United States, there were scenes of uncertainty at the few airports still permitted to receive flights from China, as the first federally required quarantine since the smallpox era a half century ago took effect. Russia, which shares a 2,600-mile border with China, suspended all passenger-rail links. In the Philippines, President Rodrigo Duterte exhorted citizens to “stop this xenophobia thing” amid signs there were acts of discrimination against people of Chinese descent.
.....
Gautam
This is a long article with lots of fotoos, please read.
I have a feeling things will get worse before it gets better.
JE Menon
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Re: Wuhan Coronavirus Resource Thread

Post by JE Menon »

https://twitter.com/jai_menon/status/12 ... 41792?s=19

Posted for what it's worth.

Dr. Francis Boyle discusses the Wuhan coronavirus outbreak & the Biosafety Level 4 laboratory from which he believes the infectious disease escaped. He thinks it's a biowarfare agent.

Dr. Boyle drafted the US Bio Weapons Anti-Terrorism Act (1989).
Philip
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Re: Wuhan Coronavirus Resource Thread

Post by Philip »

Ban anything and everything coming from China.Containers, ships- rats may bring the virus in, anyone who lives in China or has visited China,a total ban for one year at least. The Chinese have lost control over its spread and are hoping that the more countries get infected, the heat on them will lessen and they will get off the hook. They've only revealed around 300 deaths,the real figures are most likely 100 times worse.
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Re: Wuhan Coronavirus Resource Thread

Post by Mollick.R »

g.sarkar wrote:https://www.nytimes.com/2020/02/03/worl ... -sars.html

Gautam
This is a long article with lots of fotoos, please read.
I have a feeling things will get worse before it gets better.


In this article in a embedded photo NYT is showing part of J&K as paki land. :x
Mollick.R
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Re: Wuhan Coronavirus Resource Thread

Post by Mollick.R »

JE Menon wrote:https://twitter.com/jai_menon/status/12 ... 41792?s=19

Posted for what it's worth.

Dr. Francis Boyle discusses the Wuhan coronavirus outbreak & the Biosafety Level 4 laboratory from which he believes the infectious disease escaped. He thinks it's a biowarfare agent.

Dr. Boyle drafted the US Bio Weapons Anti-Terrorism Act (1989).
This point of leakage of virus from "Biosafety Level 4 laboratory" is popping up in several places in internet.
Name of country is "China" so it can not be ruled out.
Mollick.R
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Re: Wuhan Coronavirus Resource Thread

Post by Mollick.R »

https://greatgameindia.com/coronavirus-bioweapon/


Coronavirus Bioweapon – How China Stole Coronavirus From Canada And Weaponized It
By GreatGameIndia -January 26, 2020| Last modified on February 3rd, 2020 at 9:45 pm,

Chinese Biological Espionage
In March 2019, in mysterious event a shipment of exceptionally virulent viruses from Canada’s NML ended up in China. The event caused a major scandal with Bio-warfare experts questioning why Canada was sending lethal viruses to China. Scientists from NML said the highly lethal viruses were a potential bio-weapon.

Following investigation, the incident was traced to Chinese agents working at NML. Four months later in July 2019, a group of Chinese virologists were forcibly dispatched from the Canadian National Microbiology Laboratory (NML). The NML is Canada’s only level-4 facility and one of only a few in North America equipped to handle the world’s deadliest diseases, including Ebola, SARS, Coronavirus, etc.

Xiangguo Qiu – The Chinese Bio-Warfare Agent
The NML scientist who was escorted out of the Canadian lab along with her husband, another biologist, and members of her research team is believed to be a Chinese Bio-Warfare agent Xiangguo Qiu. Qiu was the head of the Vaccine Development and Antiviral Therapies Section in the Special Pathogens Program at Canada’s NML.

Xiangguo Qiu is an outstanding Chinese scientist born in Tianjin. She primarily received her medical doctor degree from Hebei Medical University in China in 1985 and came to Canada for graduate studies in 1996. Later on, she was affiliated with the Institute of Cell Biology and the Department of Pediatrics and Child Health of the University of Manitoba, Winnipeg, not engaged with studying pathogens.
But a shift took place, somehow. Since 2006, she has been studying powerful viruses in Canada’s NML. The viruses shipped from the NML to China were studied by her in 2014, for instance (together with the viruses Machupo, Junin, Rift Valley Fever, Crimean-Congo Hemorrhagic Fever and Hendra).

Infiltrating the Canadian Lab
Dr. Xiangguo Qiu is married to another Chinese scientist – Dr. Keding Cheng, also affiliated with the NML, specifically the “Science and Technology Core”. Dr. Cheng is primarily a bacteriologist who shifted to virology. The couple is responsible for infiltrating Canada’s NML with many Chinese agents as students from a range of Chinese scientific facilities directly tied to China’s Biological Warfare Program, namely:

Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun
Center for Disease Control and Prevention, Chengdu Military Region
Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei
Institute of Microbiology, Chinese Academy of Sciences, Beijing
All of the above four mentioned Chinese Biological Warfare facilities collaborated with Dr. Xiangguo Qiu within the context of Ebola virus, the Institute of Military Veterinary joined a study on the Rift Valley fever virus too, while the Institute of Microbiology joined a study on Marburg virus. Noticeably, the drug used in the latter study – Favipiravir – has been earlier tested successfully by the Chinese Academy of Military Medical Sciences, with the designation JK-05 (originally a Japanese patent registered in China already in 2006), against Ebola and additional viruses.

However, the studies by Dr. Qiu are considerably more advanced and apparently vital for the Chinese biological weapons development in case Coronavirus, Ebola, Nipah, Marburg or Rift Valley fever viruses are included therein.

The Canadian investigation is ongoing and questions remain whether previous shipments to China of other viruses or other essential preparations, took place from 2006 to 2018, one way or another.Dr. Xiangguo Qiu also collaborated in 2018 with three scientists from the US Army Medical Research Institute of Infectious Diseases, Maryland, studying post-exposure immunotherapy for two Ebola viruses and Marburg virus in monkeys; a study supported by the US Defense Threat Reduction Agency.

The Wuhan Coronavirus
Dr. Xiangguo Qiu made at least five trips over the school year 2017-18 to the above mentioned Wuhan National Biosafety Laboratory of the Chinese Academy of Sciences, which was certified for BSL4 in January 2017. Moreover, in August 2017, the National Health Commission of China approved research activities involving Ebola, Nipah, and Crimean-Congo hemorrhagic fever viruses at the Wuhan facility.

Coincidentally, the Wuhan National Biosafety Laboratory is located only 20 miles away from the Huanan Seafood Market which is the epicenter of the Coronavirus outbreak dubbed the Wuhan Coronavirus.
The Wuhan National Biosafety Laboratory is housed at the Chinese military facility Wuhan Institute of Virology linked to China’s Biological Warfare Program. It was the first ever lab in the country designed to meet biosafety-level-4 (BSL-4) standards – the highest biohazard level, meaning that it would be qualified to handle the most dangerous pathogens.

In January 2018, the lab was operational ‘for global experiments on BSL-4 pathogens,’ wrote Guizhen Wu in the journal Biosafety and Health. ‘After a laboratory leak incident of SARS in 2004, the former Ministry of Health of China initiated the construction of preservation laboratories for high-level pathogens such as SARS, coronavirus, and pandemic influenza virus,’ wrote Guizhen Wu.

Coronavirus Bioweapon
The Wuhan institute has studied coronaviruses in the past, including the strain that causes Severe Acute Respiratory Syndrome, or SARS, H5N1 influenza virus, Japanese encephalitis, and dengue. Researchers at the institute also studied the germ that causes anthrax – a biological agent once developed in Russia.

“Coronaviruses (particularly SARS) have been studied in the institute and are probably held therein,” said Dany Shoham, a former Israeli military intelligence officer who has studied Chinese biowarfare. He said. “SARS is included within the Chinese BW program, at large, and is dealt with in several pertinent facilities.”

James Giordano, a neurology professor at Georgetown University and senior fellow in Biowarfare at the U.S. Special Operations Command, said China’s growing investment in bio-science, looser ethics around gene-editing and other cutting-edge technology and integration between government and academia raise the spectre of such pathogens being weaponized.

That could mean an offensive agent, or a modified germ let loose by proxies, for which only China has the treatment or vaccine. “This is not warfare, per se,” he said. “But what it’s doing is leveraging the capability to act as global saviour, which then creates various levels of macro and micro economic and bio-power dependencies.”

China’s Biological Warfare Program
In a 2015 academic paper, Shoham – of Bar-Ilan’s Begin-Sadat Center for Strategic Studies – asserts that more than 40 Chinese facilities are involved in bio-weapon production.China’s Academy of Military Medical Sciences actually developed an Ebola drug – called JK-05 — but little has been divulged about it or the defence facility’s possession of the virus, prompting speculation its Ebola cells are part of China’s bio-warfare arsenal, Shoham told the National Post.

Ebola is classified as a “category A” bioterrorism agent by the U.S. Centers for Disease Control and Prevention, meaning it could be easily transmitted from person to person, would result in high death rates and “might cause panic.” The CDC lists Nipah as a category C substance, a deadly emerging pathogen that could be engineered for mass dissemination.

China’s Biological Warfare Program is believed to be in an advanced stage that includes research and development, production and weaponization capabilities. Its current inventory is believed to include the full range of traditional chemical and biological agents with a wide variety of delivery systems including artillery rockets, aerial bombs, sprayers, and short-range ballistic missiles.

Weaponizing Biotech
China’s national strategy of military-civil fusion has highlighted biology as a priority, and the People’s Liberation Army could be at the forefront of expanding and exploiting this knowledge.
The PLA is pursuing military applications for biology and looking into promising intersections with other disciplines, including brain science, supercomputing, and artificial intelligence. Since 2016, the Central Military Commission has funded projects on military brain science, advanced biomimetic systems, biological and biomimetic materials, human performance enhancement, and “new concept” biotechnology.

In 2016, an AMMS doctoral researcher published a dissertation, “Research on the Evaluation of Human Performance Enhancement Technology,” which characterized CRISPR-Cas as one of three primary technologies that might boost troops’ combat effectiveness. The supporting research looked at the effectiveness of the drug Modafinil, which has applications in cognitive enhancement; and at transcranial magnetic stimulation, a type of brain stimulation, while also contending that the “great potential” of CRISPR-Cas as a “military deterrence technology in which China should “grasp the initiative” in development.

In 2016, the potential strategic value of genetic information led the Chinese government to launch the National Genebank, which intends to become the world’s largest repository of such data. It aims to “develop and utilize China’s valuable genetic resources, safeguard national security in bioinformatics, and enhance China’s capability to seize the strategic commanding heights” in the domain of Biotechnology Warfare.

Chinese military’s interest in biology as an emerging domain of warfare is guided by strategists who talk about potential “genetic weapons” and the possibility of a “bloodless victory.”
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Re: Wuhan Coronavirus Resource Thread

Post by vishvak »

https://www.nature.com/news/inside-the- ... ns-1.21487
Future plans include studying the pathogen that causes SARS, which also doesn’t require a BSL-4 lab, before moving on to Ebola and the West African Lassa virus, which do
..
The SARS virus has escaped from high-level containment facilities in Beijing multiple times, notes Richard Ebright, a molecular biologist at Rutgers University ..
..

..
But Ebright is not convinced of the need for more than one BSL-4 lab in mainland China. He suspects that the expansion there is a reaction to the networks in the United States and Europe, which he says are also unwarranted. He adds that governments will assume that such excess capacity is for the potential development of bioweapons.
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Re: Wuhan Coronavirus Resource Thread

Post by Mollick.R »

Updates (Courtesy TOI live updates)
https://timesofindia.indiatimes.com/ind ... 921930.cms

Automakers close factories in China due to virus outbreak

* Ford Motor plans to resume production on Feb 10 at its factories in Chongqing and Hangzhou with joint venture partner Chongqing Changan Automobile after an extended Chinese New Year break. * Honda plans to extend the closure period for its three car plants in Wuhan, which it operates with Dongfeng Group , until Feb. 13. * Hyundai Motor said it will suspend production in South Korea due to the coronavirus outbreak disrupting parts supply, becoming the first major automaker to do so outside China.


The city of Taizhou, parts of Hangzhou -- including the district that is home to the headquarters of Chinese tech giant Alibaba -- and some of Ningbo will only allow one person per household to go outside every two days to buy necessities, city officials said.

Around 12 million people are affected by the new restrictions, adding to the tens of millions of people already quarantined in and around Wuhan, ground zero for 2019-nCoV.

More Chinese cities, including one just 175 kilometres (110 miles) from Shanghai, were put under lockdown on Tuesday, as the impact of a deadly new virus spread further from its epicenter.

Disabled boy dies after being left to fend for himself when his father is quarantined over coronavirus in China: AFP

The death toll in China's coronavirus rose sharply to 425 with 64 deaths on Monday and the number of those infected with the deadly disease rose to 20,438, Chinese health authorities said on Tuesday.


The city of Taizhou and three districts of the city of Hangzhou -- including the area with the main office of Chinese tech giant Alibaba -- will now only allow one person per household to go outside every two days to buy necessities, AFP quoting officials.

Chinese city of Hangzhou locks down three districts over virus fears: AFP quoting authorities
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Re: Wuhan Coronavirus Resource Thread

Post by arshyam »

So from Hubei province, the infection has spread to neighbouring provinces?

Hangzhou is ~520 km from Wuhan as the crow flies, Ningbo is ~650km, and Taizhou is around 680. These are not small distances, and Ningbo and Taizhou are on the Chinese east coast. This is becoming problematic - Shanghai is just across the Hangzhou bay.
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Re: Wuhan Coronavirus Resource Thread

Post by John »

arshyam wrote:So from Hubei province, the infection has spread to neighbouring provinces?

Hangzhou is ~520 km from Wuhan as the crow flies, Ningbo is ~650km, and Taizhou is around 680. These are not small distances, and Ningbo and Taizhou are on the Chinese east coast. This is becoming problematic - Shanghai is just across the Hangzhou bay.
It is because spread start happening in December most of market worker came down sick and given most of Chinese workers travel back to home to their holidays it is easy to see how it spread.

In US Fed and Trump are doing wonderful job downplaying the risk ( any Chinese coverup plays into their hands) so they pump up the market and dump the stocks before bad news hits. Already seeing crazy amount of money flowing into treasuries from big money players.

Added: Singapore confirmed 6 more cases. But WHO said it is not pandemic and Fed said no impact to US economy, since WHO and Fed are always right expect a huge rally in equities.
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Re: Wuhan Coronavirus Resource Thread

Post by Philip »

The bio- warfare virus was meant according to some analysts as one of the options to decimate India without having uo go to war.
Fortunately for us,it broke freefrom ots lab and is unleashing its ferocity first upon the Chin people. The GOI should take the most stringent measures to prevent the virus from spreading into India which will cripple the country if it spreads as it has done in China.

China should be internationally quarantined,no one gets in,no ond gets out. No goods get out in ships carrying cargoes and containers which might have the virus in both human and vermin carriers. There should be anindefinite blanket ban on any merchantman from travelling to Chin ports,plus a ban on Chinese fishing vessels from fishing in international waters,etc. A totsl quarantine until the virus is contained and the death and infection rate start falling according to WHO/ UN health officials,not the cheating Chinese who concealed the plague from the world.
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Re: Wuhan Coronavirus Resource Thread

Post by Tuan »

madhu
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Re: Wuhan Coronavirus Resource Thread

Post by madhu »

Putting the dots without connecting them on novel coronavirus (2019 nCoV)

Dot 1) BSL4 lab in china is located in wuhan where 2019 nCoV started.

Dot 2) Jul 14, 2019, CBC News, states Chinese researcher escorted out of BSL4 lab canada. Cheng has published research papers on HIV infections, Severe Acute Respiratory Syndrome (SARS), E. coli infections and Creutzfeldt-Jakob Syndrome.

Dot 3) October 18, 2019 co-hosted by the Johns Hopkins Center for Health Security and Bill & Melinda Gates Foundation conducted, An exercise simulated the outbreak of a novel coronavirus, modelled largely on SARS, with no known vaccines code name "Event 201"

Dot 4) first anounsement of outbrack of 2019 nCoV on Jan 2020

Dot5 ) jan 27 2020, CBC News, publishs "
Online claims that Chinese scientists stole coronavirus from Winnipeg lab have 'no factual basis'"

Dot 6) lanset, medical journal publish a paper on jan 30 2020, that states 2019 nCoV fatality of 11%, infection of 85% within 6 feet. WHO states Ro = 2.5 to 5

Dot 7) jan 31, 2020, indian scientest publish paper on Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1

Dot 8) Feb 2, 2020 thai doctor reports cocktail of flu and HIV drugs to treat coronavirus cases with success
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Re: Wuhan Coronavirus Resource Thread

Post by SRajesh »

https://timesofindia.indiatimes.com/ind ... 921930.cms
More than 20,000 confirmed cases, death toll crosses 400 and supposedly more than 2/3rd of those are men.
If it were to affect children/old/infirm/immune compromised, these figures don't add up.
What the hell am I missing here???? :eek: :eek:
Somehow it doesn't add up!
The old pandemics claimed the children/old/infirm first before moving on the Mard-momeen(aka healthy!!! :lol: :lol: )
But this is different! why??? :roll:
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Re: Wuhan Coronavirus Resource Thread

Post by John »

^ A lot of people playing it down either have distrust of China or have financial interest, a lot of small hedge fund shorted the market Friday and got burned today. I am betting some of bigger player/funds were behind the news playing up WHO report that it is not a pandemic, news articles like Flu kills 8000 etc and reaped the rewards when markets popped up today.
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Re: Wuhan Coronavirus Resource Thread

Post by Aarvee »

Vayutuvan wrote:
I have a technical question - how long does it take to sequence a virus? How long are the amino acid molecules? (is that the right question at all?)

It is the DNA that is sequenced. For RNA viruses, RNA is extracted, reverse transcribed into cDNA and then sequenced. The amino acid sequence is derived from the genetic material.

During epidemics, depending on the technology used, the pathogen can be sequenced within 24 hrs.

For perspective, here is a review. Surprise surprise, the authors are from Wuhan Institute of Virology.

https://link.springer.com/content/pdf/1 ... 9596-x.pdf

A quote from this paper- "Even in an environment with resource limited areas, it can produce results in 24 h or less, after receiving a positive Ebola sample,and the sequencing process takes only 15–60 min, providing a good example for epidemic surveillanc"
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Re: Wuhan Coronavirus Resource Thread

Post by Vayutuvan »

Arun.prabhu wrote:There are apparently 30 incinerators to burn bodies in Wuhan. They are operating at Full capacity per reports.
Assuming approximately 1.5 hrs. per cremation (provided these incinerators are normal crematorium type, not industrial grade), then we have ~ 500 bodies incinerated per day by the 30 incinerators. Let us say they operated these for 15 days giving us ~7500 dead.
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Re: Wuhan Coronavirus Resource Thread

Post by Vayutuvan »

Aarvee wrote:A quote from this paper- "Even in an environment with resource limited areas, it can produce results in 24 h or less, after receiving a positive Ebola sample,and the sequencing process takes only 15–60 min, providing a good example for epidemic surveillanc"
It is pretty fast. So every country that had a case would have sequenced it. India has the sequencing technology at many places across the country. There is a well-known Virology institute in Pune, IIRC.
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Re: Wuhan Coronavirus Resource Thread

Post by nachiket »

Rsatchi wrote:https://timesofindia.indiatimes.com/ind ... 921930.cms
More than 20,000 confirmed cases, death toll crosses 400 and supposedly more than 2/3rd of those are men.
If it were to affect children/old/infirm/immune compromised, these figures don't add up.
What the hell am I missing here???? :eek: :eek:
Somehow it doesn't add up!
The old pandemics claimed the children/old/infirm first before moving on the Mard-momeen(aka healthy!!! :lol: :lol: )

But this is different! why??? :roll:
There have been past epidemics/pandemics where the infection can be deadlier in healthy young adults with strong immune systems. This may be due to what is known as a cytokine storm (or cytokine release syndrome) in which the body's strong immune response itself leads to a lot of damage.

This is one possible explanation of the high mortality rate of the Spanish Flu epidemic of 1918. Even a SARS infection can trigger cytokine release syndrome.

Having said that, let me make it very clear that there is no evidence as of now that I am aware of which states that this can happen in case of the current novel Coronavirus infection.
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Re: Wuhan Coronavirus Resource Thread

Post by sanjaykumar »

From the introduction.....


Emerging and re-emerging infectious diseases have given
rise to a large number of human infections, morbidity, and
heavy economic burden, including the Middle East respiratory syndrome caused by a coronavirus in 2012, global
influenza pandemic caused by the H7N9 influenza A virus in
2013, Ebola epidemic in West Africa in 2014, and Lassa
fever epidemic in Nigeria in 2019. The healthcare war
against viruses deserves constant surveillance due to the
continuous emergence of new viruses and rapid evolution of
existing viruses (Liu and Liu, 2017).



That's the credibility of Chinamen...no mention of the obvious, SARS.
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Re: Wuhan Coronavirus Resource Thread

Post by Amber G. »

Vayutuvan wrote:
I have a technical question - how long does it take to sequence a virus? How long are the amino acid molecules? (is that the right question at all?)
It's is fairly fast. Also it is mutating - so this is very helpful to know exact sequence in diagnosis..

A good update link: (with all sorts of links)
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Re: Wuhan Coronavirus Resource Thread

Post by madhu »

Vayutuvan wrote: It is pretty fast. So every country that had a case would have sequenced it. India has the sequencing technology in many places across the country. There is a well-known Virology institute in Pune, IIRC.
Yes, it is sequenced and published. In fact, it is chines did it first and released full sequence. Here is the sequence if u r interested.
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Re: Wuhan Coronavirus Resource Thread

Post by CalvinH »

Philip wrote:Ban anything and everything coming from China.Containers, ships- rats may bring the virus in, anyone who lives in China or has visited China,a total ban for one year at least. The Chinese have lost control over its spread and are hoping that the more countries get infected, the heat on them will lessen and they will get off the hook. They've only revealed around 300 deaths,the real figures are most likely 100 times worse.
My company as asked those who have returned from Business travel from China to work from home for next 2 weeks. Same for those who are living with those who have returned from China in past 1 week.
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Re: Wuhan Coronavirus Resource Thread

Post by UlanBatori »

CalvinH wrote:
UlanBatori wrote:Why is it that we don't hear of these massive virus outbreaks in say, South America (Heaven forbid!) Rio de Janeiro and Mexico City match Wuhan and Shanghai in crowding and pollution and are probably far worse in sanitation, food hygeine and also sex habits, come to think of it.
China has a long list of these now. But none from South Am. Nor from Pakistan :((
May be because of Chinese diet preferences that increases the chances of extended exposure of virus carrying wild animals with humans. Viruses that mutate in wild and would have died with their carriers are bought to markets and co-mingled with other produce and exposed to humans for extended duration (transporting, storage and selling).
Calvinji, South American diet is very heavily meat-based, and they eat practically all species. I think the answer is that zillions of virus strains come out and bite ppl in the Amazon regions and Andes and the Pampas every year. Thousands of people die of infection. But CNN/WaPo aren't there to hype it.
Gotta have some empathy for the cheen in this, as much as I may take pleasure in poking them on other things.
They have high density of population in urban PRC, and their people are hard-working and productive, so they are missed if they lose days due to illness. This is why they react fast to these things - and the Usual Quarters go to town sneering at them.

Glad someone looked up the flu statistics that UBCN cited. Compared to that, this CV is nothing. Flu keeps mutating, so that flu shot is bypassed every 2 or 3 years, and one get slammed by an increasingly evil new version.
John
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Re: Wuhan Coronavirus Resource Thread

Post by John »

UlanBatori wrote:
CalvinH wrote: May be because of Chinese diet preferences that increases the chances of extended exposure of virus carrying wild animals with humans. Viruses that mutate in wild and would have died with their carriers are bought to markets and co-mingled with other produce and exposed to humans for extended duration (transporting, storage and selling).
Calvinji, South American diet is very heavily meat-based, and they eat practically all species. I think the answer is that zillions of virus strains come out and bite ppl in the Amazon regions and Andes and the Pampas every year. Thousands of people die of infection. But CNN/WaPo aren't there to hype it.
Gotta have some empathy for the cheen in this, as much as I may take pleasure in poking them on other things.
They have high density of population in urban PRC, and their people are hard-working and productive, so they are missed if they lose days due to illness. This is why they react fast to these things - and the Usual Quarters go to town sneering at them.

Glad someone looked up the flu statistics that UBCN cited. Compared to that, this CV is nothing. Flu keeps mutating, so that flu shot is bypassed every 2 or 3 years, and one get slammed by an increasingly evil new version.
Once again Flu is seasonal if this were to spread like the flu all year around with little immunity and 2-3% mortality rate you are talking hundreds of thousands dying with 10+ million hospitalized for weeks. Even worse this can mutate and develop into more deadlier SARS like virus with ability to spread like Coronavirus.
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Re: Wuhan Coronavirus Resource Thread

Post by Amit Patel »

https://coronavirus.app/toll?mode=infected

Handy weburl with daily updates.
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Re: Wuhan Coronavirus Resource Thread

Post by Arun.prabhu »

Nod. You expect people to drop dead during some godforsaken disease epidemic in Congo - the doctors being very small in number, the tribes having no trust in medicine etc - but if one can be bothered to do a search, one can easily find a dozen or more videos of Chinese citizens lying dead in the middle of a street. I watched one video of a purported Chinese guy sitting at a desk one second and then having a fix and dropping to the floor and reportedly entering death throes from the disease. Combine with the incinerator claims - and as with the dead on streets videos, there are multiple independent confirmations - it indicates the Chinese resources in Wuhan are stretched beyond the breaking point and given the panicky reactions by the leadership, they are near or approaching breaking point elsewhere.
Vayutuvan wrote:
Arun.prabhu wrote:There are apparently 30 incinerators to burn bodies in Wuhan. They are operating at Full capacity per reports.
Assuming approximately 1.5 hrs. per cremation (provided these incinerators are normal crematorium type, not industrial grade), then we have ~ 500 bodies incinerated per day by the 30 incinerators. Let us say they operated these for 15 days giving us ~7500 dead.
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Re: Wuhan Coronavirus Resource Thread

Post by Arun.prabhu »

Well, maybe it’s not the end of the world after all...

https://www.nature.com/articles/s41422-020-0282-0

2019-nCoV is responding to chloroquine in the lab. The anti-malaria drug is mass produced and available in enough quantities that we can shut this thing down. So, best or middling case is most likely at this point. If this works as advertised, the worst case i outlined is now pretty much eliminated.
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Re: Wuhan Coronavirus Resource Thread

Post by John »

Arun.prabhu wrote:Well, maybe it’s not the end of the world after all...

https://www.nature.com/articles/s41422-020-0282-0

2019-nCoV is responding to chloroquine in the lab. The anti-malaria drug is mass produced and available in enough quantities that we can shut this thing down. So, best or middling case is most likely at this point. If this works as advertised, the worst case i outlined is now pretty much eliminated.
FYI this news was tweeted multiple times from shady sources, China and Pharma company Gilead have cautioned this is preliminary and against false statements that this can stop the virus before more testing.

Also news broke that a cure has been developed by Chinese media by Reuters. This caused the futures to spike (Dow 30k here we come), Chinese media deny and WHO had to come forward there is no such thing and this is fake. Looks like big institutions and hedge funds in US are spreading fake news trying to push the markets higher so they can short it for 2x profit. Expect this to happen over next months as big money tries to cash in on market volatility. Wow pushing fake news to create false hope and misery so you can make $$ greed knows no limits.

https://www.cnbc.com/2020/02/05/coronav ... dates.html

Stock futures turned higher in overnight trading after Reuters said a Chinese TV media outlet had reported that a research team at Zhejiang University had found an effective drug to treat people with the new coronavirus. The news agency, citing traders, suggested this was a reason for the move higher in stocks.

7:50 pm: WHO spokesperson reportedly says there are ‘no known’ effective drug treatments against coronavirus
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