Wuhan Coronavirus Resource Thread

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IndraD
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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 May 2020 00:07

mappunni wrote:Now that Oxford University has tied up with AstraZeneca, how does it impact the Serum Institute of India, which is also supposed to be making the same vaccine?
r
India has the mass manufacturing capacity of the vaccine hence Oxford uni will continue to collaborate with India's serum institute. This is also possible India starts producing vaccine before UK.

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 03 May 2020 01:17

https://www.sciencemag.org/news/2020/04 ... ronavirus#
New York clinical trial quietly tests heartburn remedy against coronavirus
________
GoI has taken note.
https://theprint.in/health/40-paise-a-p ... up/412763/
40-paise a pill antacid is new hope to treat Covid, Modi govt wants to stock up
Modi govt has taken note of the buzz surrounding famotidine, and asked drug authorities to assess its domestic availability and production capacity.

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 03 May 2020 01:49

Are we carrying out any trials within the country? with any existing drug?

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Re: Wuhan Coronavirus Resource Thread

Postby sanjaykumar » 03 May 2020 02:28

For what it’s worth, a man from Hong Kong put the Wuhan death toll at 80,000.

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Re: Wuhan Coronavirus Resource Thread

Postby sanjaykumar » 03 May 2020 04:11

The crimes of China documented. Good to read in its entirety for the rapacity and mendacity of the Chinese. They doubly endangered people's lives.

https://globalnews.ca/news/6858818/coro ... -shortage/

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Re: Wuhan Coronavirus Resource Thread

Postby sanjaykumar » 03 May 2020 04:21

^^^Finally some good research on understanding the protein receptors on the Chinese virus. But still surprised it took so long to record them, which I presume would be a case of seeing the virus under a electron microscope and recognizing the protein structure? Even the Chinese haven't brought out any such detailed analysis, although they knew about it since January.




They cloned most of the genes in the Chinese virus and expressed them (translated them into the physical proteins), subsequently used affinity chromatography to have human protein 'soup' bind to the viral proteins and washing out unbound human proteins. They used mass spectroscopy to identify the human proteins that interact with the viral ones.

They used pre-existing data banks to help identify drugs for repurposing. A lot of work, hence the time taken.

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Re: Wuhan Coronavirus Resource Thread

Postby Gerard » 03 May 2020 08:44

COVID-19 vaccine in 1 month? CSIR pins hope on Sepsivac
How does Sepsivac work?

It contains heat-killed mycobacterium w (Mw), an immunomodulator, which is a non-pathogenic mycobacterium.

"Normally when you develop a vaccine, you grow the organism and kill it. It is called heat killed. Here we heat killed the bacteria. It is a standard vaccine concept," Vishwakarma said, adding that the bacterium is produced by fermentation.

"The treatment we are testing against Covid-19 is designed to enhance innate immunity which is very critical. People who are weak in innate immunity will get the infection faster," he said.

Vishwakarma explained that it is a non-specific vaccine which could be used to both cure and protect people. He explained that there are generally three types of vaccines.

"There are therapeutic vaccines, where you give them as a drug for curing. There are prophylactic vaccines, which you give to people to protect them. And there are some which have both the properties, which are called immunomodulators.

"Sepsivac will be an immunomodulator, which will have protective effect and therapeutic effect both," he said.

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Re: Wuhan Coronavirus Resource Thread

Postby Deans » 03 May 2020 10:21

SRoy wrote:When the shutdown was announced the total countrywide infected count was odd 200. If the transport were available people would have left for their native places. The infection itself was limited to returnees from overseas travel. The working classes had no contact whatsoever with these people.

But, now we are opening the transports against a backdrop of 30K odd cases, combined with the fact that all recent infection/transmission are going through medical personnel, police personnel, civic service workers. The migrant population taking the transport will come in contact with these govt. staff. Once that happens the compact environment inside buses and trains will make in worse.

There is already a report of a single batch migrants returning from Maharashtra tested for 41 people positive.


We had 649 cases when the lockdown was announced. However, we were testing under 2000/ day and it was limited to foreign returnees with symptoms and their immediate contacts, or those with advanced symptoms. As we now know, there were a large no of asymptomatic cases and also a lot of untested contacts of positive cases, who if allowed to run unchecked, would have caused more havoc. However, I take the point that migrant workers were largely free of the virus and their movement could have been better handled.

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Re: Wuhan Coronavirus Resource Thread

Postby tandav » 03 May 2020 12:42

https://www.news18.com/news/tech/aarogy ... 01633.html

Aarogya Setu is a gem in the making. It should become like the BHIM/UPI call it United Health Interface (UHI)

Features implemented so far
1) Auto contact tracing via blue tooth and gps
2) Self assessment
3) Whether tested for COVID and/or positive or not
4) infections reported within 1 KM of your location
5) Helpline
6) Validated information sharing (not social non validated activity

Future features (my suggestions)
1) Telemedicine
2) adding health records of users
3) Integration with AADHAR

There are privacy concerns but if we can make the data user owned and only some data shared by government. The data will spur innovation like never before, guide healthcare development, vaccination guides, preventive healthcare, insurance etc

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 03 May 2020 13:22

SARS-CoV-2 (COVID-19) Testing: Status Update:
A total of 1046450 samples have been tested as on 3 May 2020, 9 AM IST.


23 April 2020 - 500542
24 April 2020 - 541789
25 April 2020 - 579957
26 April 2020 - 625309
27 April 2020 - 665819
28 April 2020 - 716733
29 April 2020 - 770764
30 April 2020 - 830201
1 May 2020 - 902654
2 May 2020 - 976363
3 May 2020 - 1046450

According to covid19india.org, 2567 confirmed cases were reported yesterday.

70087 tested, 3.66% positive.

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Re: Wuhan Coronavirus Resource Thread

Postby vimal » 03 May 2020 13:47

New Warning Of Rare Coronavirus Complication In Children | NBC Nightly News
:eek: :eek:

There have been nearly 100 reported cases in the U.S. and Europe of a condition thought to be linked to coronavirus in children. Leading doctors joined the World Health Organization, CDC and NIH to exchange information


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Re: Wuhan Coronavirus Resource Thread

Postby Kaivalya » 03 May 2020 17:59

Deans wrote:
SRoy wrote:When the shutdown was announced the total countrywide infected count was odd 200.

But, now we are opening the transports against a backdrop of 30K odd cases, combined with the fact that all recent infection/transmission are going through medical personnel, police personnel, civic service workers. The migrant population taking the transport will come in contact with these govt. staff. Once that happens the compact environment inside buses and trains will make in worse.

There is already a report of a single batch migrants returning from Maharashtra tested for 41 people positive.


However, I take the point that migrant workers were largely free of the virus and their movement could have been better handled.



SRoy sir - infected count was really unknown. Hence the lockdown.That is still the problem...infected people are largely asymptomatic.

The limited testing at that time confirmed it to be 200 with no protocols established, nothing mobilized. You are missing that tablighi alone caused 85% of the cases in TN till about a week ago. Unfortunately for the first line warriors (cops, vegetable vendors in a market, doctors ,nurses ) are infected now because of people hiding their travel/contact history or wantonly. If you think 41 migrants in a batch who have been carefully tested is a problem then you are underestimating 2 weeks of state government machinery and central government wrangling over protocol (with nothing known/done at that time) and we will be far worse than any other country now. Just 2 states kerala and west bengal keep arguing against central government ( "you are not my prime minister" or "constitutional rights" etc) .

Like Deansji says - migrants could have been better handled like yogiji did in the beginning. The unfortunate truth of the matter is no state had any idea about how many migrant laborers were present even to contemplate any action. Even kerala called them "guest workers" and promised to take care of them where they are. I know TN did a good job taking care of them

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Re: Wuhan Coronavirus Resource Thread

Postby SRoy » 03 May 2020 20:23

^^
There is a loophole in your argument.
If we are discovering infections now, that means they were infected around 2nd or 3rd week of April.
Why should we second guess and assume people at large were infected and undetected around 23rd of March? It wasn't the case.

To my knowledge there is not a single case in my office, acquaintances and friend circle that travelled to home towns on 21st/22nd/23rd/24th have been diagnosed with any illness.
Testing or no testing seriously ill people will show up at medical facilities? Yes or no? That didn't happen around mid-April.

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Re: Wuhan Coronavirus Resource Thread

Postby yensoy » 03 May 2020 21:32

Chennai infected count is starting to look very startling. The counts are going up by record numbers every day, i.e. still clearly on exponential growth path despite appearing to ease off earlier.

So one would typically expect the state government to implement a rather strict lockdown of the city till the numbers subside. However (beside a 4 day rigorous lockdown implemented last week) tomorrow onwards a lot of things are opening up including standalone shops in the city with relatively long operating hours.

That can only mean one thing - the newly found to be infected are already confined to the existing hotspots and containment areas (and these are already barricaded). Further it would also mean that random testing being done outside of hotspots hasn't shown any positives.

This is only a theory. There is very little public information available in terms of locations of new cases.

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Re: Wuhan Coronavirus Resource Thread

Postby vishvak » 03 May 2020 21:40

vimal wrote:New Warning Of Rare Coronavirus Complication In Children | NBC Nightly News
:eek: :eek:

[quote>>>
There have been nearly 100 reported cases in the U.S. and Europe of a condition thought to be linked to coronavirus in children. Leading doctors joined the World Health Organization, CDC and NIH to exchange information
[/<<<quote]
[youtube]>>NIuIroDcvio[/youtube]

Because of pseudo secular rhetoric a point was missed somewhere that Tablighi and such are religious orgs are zealous in proselytizing and will repeat the moment left unchecked.

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Re: Wuhan Coronavirus Resource Thread

Postby Deans » 03 May 2020 22:29

The figures of the last 3 days have made me less optimistic for the first time since it began. My guess was that we would peak in the latter part of April (in terms of new cases/day) with about 1000 fatalities. That has not happened.

Punjab, TN, Delhi and Gujarat have reported their highest figures today. Earlier only Gujarat was seen as a problem, with cases in the high 200s each day. On the positive side, Punjab (plus today's spike in Haryana and possibly Delhi) seem to be the Nanded Gurudwara returnees - all of whom have now been tested. In Gujarat 90% of cases are from 10% of the city - the old walled city. There was a similar situation in Jaipur and Indore which both seem to be coming under control. I believe every other state has peaked.

The optimist in me expects by the end of next week
-11 States or UT's being virus free or getting there (no new cases for a week). Assam and Himachal being the biggest
- Kerala, Karnataka, Telengana, Andhra and Haryana having recoveries > new cases each day.
- Mumbai under 700 cases/ day each day, Delhi and Gujarat under 300/day. TN,UP, MP, Raj each under 150/day.

Question mark over WB. I see today's spike as a positive, the community is beginning to acknowledge that they need to be counted in order to
be cured.

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Re: Wuhan Coronavirus Resource Thread

Postby Kaivalya » 03 May 2020 22:42

SRoy wrote:^^
There is a loophole in your argument.
If we are discovering infections now, that means they were infected around 2nd or 3rd week of April.
Why should we second guess and assume people at large were infected and undetected around 23rd of March? It wasn't the case.

To my knowledge there is not a single case in my office, acquaintances and friend circle that travelled to home towns on 21st/22nd/23rd/24th have been diagnosed with any illness.
Testing or no testing seriously ill people will show up at medical facilities? Yes or no? That didn't happen around mid-April.


SRoy sir - your circle knowledge seems anecdotal. Please look at the ratio of seriously ill people to infected people.

The point is that we couldn't assume that **people were not infected** either. Even now entire blocks are being designated as containment zones because of the assumption that more could be infected inthat area who have not been tested and confirmed negative. The rapid test kits were found ineffective and were sent back.

Last from me on this line of reasoning

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Re: Wuhan Coronavirus Resource Thread

Postby vimal » 03 May 2020 23:58

https://www.youtube.com/watch?v=J9Vh9yqu5Qo

The U.S. intelligence report says China not only misled the world on the severity of the virus, but also stockpiled medical supplies and PPE.



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Re: Wuhan Coronavirus Resource Thread

Postby DavidD » 04 May 2020 02:08

vimal wrote:https://www.youtube.com/watch?v=J9Vh9yqu5Qo

The U.S. intelligence report says China not only misled the world on the severity of the virus, but also stockpiled medical supplies and PPE.




Who isn't stockpiling PPEs these days? If China didn't stockpile them the story would be how the Chinese government is sacrificing healthcare workers' lives in order to make a quick buck selling much needed PPEs to foreigners.

Besides, I'm 100% confident that China has exported more PPEs than it has imported...after meeting its own internal supply requirements that is.

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Re: Wuhan Coronavirus Resource Thread

Postby saip » 04 May 2020 02:28

^^^ Possibly it did. But selling the same PPEs at eight times the original cost (Mexico case) will make even Shylock proud.

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Re: Wuhan Coronavirus Resource Thread

Postby DavidD » 04 May 2020 05:14

saip wrote:^^^ Possibly it did. But selling the same PPEs at eight times the original cost (Mexico case) will make even Shylock proud.


Sure, but that's just economics, not a result of hoarding. Mask production world-wide pre-COVID was at about 20 million a day, of which about half were produced in China. By the end of February China alone was producing about 120 million a day, and probably more now. Whatever China could hoard in January would be a drop in the bucket compared to what they're putting out these days.

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Re: Wuhan Coronavirus Resource Thread

Postby Raveen » 04 May 2020 07:37

DavidD wrote:
saip wrote:^^^ Possibly it did. But selling the same PPEs at eight times the original cost (Mexico case) will make even Shylock proud.


Sure, but that's just economics, not a result of hoarding. Mask production world-wide pre-COVID was at about 20 million a day, of which about half were produced in China. By the end of February China alone was producing about 120 million a day, and probably more now. Whatever China could hoard in January would be a drop in the bucket compared to what they're putting out these days.



So grateful to China for providing PPEs at 8x the regular price despite the shortages cause by a pandemic that at best originated from its own unhygienic "wet markets" (or worse from a lab) that have now caused the third pandemic in a short period of time.

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 04 May 2020 12:07

SARS-CoV-2 (COVID-19) Testing: Status Update:
A total of 1107233 samples have been tested as on 4 May 2020, 9 AM IST.


23 April 2020 - 500542
24 April 2020 - 541789
25 April 2020 - 579957
26 April 2020 - 625309
27 April 2020 - 665819
28 April 2020 - 716733
29 April 2020 - 770764
30 April 2020 - 830201
1 May 2020 - 902654
2 May 2020 - 976363
3 May 2020 - 1046450
4 May 2020 - 1107233

According to covid19india.org, 2717 confirmed cases were reported yesterday.

60783 tested, 4.46% positive.

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Re: Wuhan Coronavirus Resource Thread

Postby kumarn » 04 May 2020 14:09

saip wrote:^^^ Possibly it did. But selling the same PPEs at eight times the original cost (Mexico case) will make even Shylock proud.


The current CCP has to be the most uncouth, uncivilized, barbaric bunch ever as shown by the way they have handled themselves. They just had not had the opportunity to kill at a larger scale.

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Re: Wuhan Coronavirus Resource Thread

Postby sajo » 04 May 2020 15:36

It seems we would need another 15 days to see the true effect of lockdown relaxation on the case numbers. I can see a few internal roads from my window and the traffic is easily 10x the usual crowds today. Kids, Elders, Women, youngsters all out at the same time. Hardly any masks seen. And this is in Pune, where, along with Mumbai, restrictions are supposed to continue.
Oh well..

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 04 May 2020 15:38

People are irresponsible. What else can we say.

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Re: Wuhan Coronavirus Resource Thread

Postby Larry Walker » 04 May 2020 16:47

The point here is that China kept telling that there was no pandemic and it is not human transmittable then why was it stocking masks and PPE's. Stocking PPE's en masse means that they knew it is of pandemic proportions and human transmittable. They selling it back 8-times the price is just one more example of how heartless and self-centered Chinese society is.

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Re: Wuhan Coronavirus Resource Thread

Postby Kaivalya » 04 May 2020 17:54


Philip
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Re: Wuhan Coronavirus Resource Thread

Postby Philip » 04 May 2020 18:13

Can't confirm but a reliable source said that info from China said that the Chins are back to normal because of two simple procedures.Sipping hot water frequently and 4 salt,steam inhalations daily. Ozone therapy also uses saline in the drip along with ozonated oxygen to increase oxygen in the blood while the saline kills the bug.Bisleri use ozone to sterilise their mineral water and are making ozone sterilisation cabins for medical staff for Bombay hospitals. The Ozone Foundationbof India has its HQ in Pune. They are waiting for the green light for trials in MH,but ICMR procedures- no relief to anyone,are a stumbling block.

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 04 May 2020 19:11

Philip wrote:Can't confirm but a reliable source said that info from China said that the Chins are back to normal because of two simple procedures.Sipping hot water frequently and 4 salt,steam inhalations daily.

Doing hot water sipping & stream inhalations daily (at least twice a day)...

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Re: Wuhan Coronavirus Resource Thread

Postby madhu » 04 May 2020 21:32

Kaivalya wrote:On why herd immunity is wishful thinking :

https://foreignpolicy.com/2020/05/02/herd-immunity-india-coronavirus-pandemic/



Nearly 40 percent of Indian adults aged 45-54 and 22 percent of those aged 20-44 have hypertension; nearly 4 percent of adults aged 15-44 years have reported Type 2 diabetes, along with a high rate of unreported cases; and 2.1 million people are living with HIV, of whom 83 percent are between 15 and 45 years old. Finally, the prevalence of chronic pulmonary disease and asthma among adults was reported as 4.2 and 3 percent, respectively, and nearly a third of adults use tobacco.


Is there any location where i can get data to cross check this? I cant find simple data like how many are in ICU for what condition ( like ICNARC) or weekly death reports like ( like euromomo.eu)
I read that death by other health problems has reduced significantly... Need to verify if true...

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Re: Wuhan Coronavirus Resource Thread

Postby chola » 04 May 2020 21:46

Zynda wrote:
Philip wrote:Can't confirm but a reliable source said that info from China said that the Chins are back to normal because of two simple procedures.Sipping hot water frequently and 4 salt,steam inhalations daily.

Doing hot water sipping & stream inhalations daily (at least twice a day)...


Too good to be true ...

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Re: Wuhan Coronavirus Resource Thread

Postby sudarshan » 04 May 2020 21:53

chola wrote:
Zynda wrote:Doing hot water sipping & stream inhalations daily (at least twice a day)...


Too good to be true ...


They say steam inhalation will make pneumonia way worse. Pneumonia=water logging in lungs, and steam will add to that. Please consult a doctor before doing anything.

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Re: Wuhan Coronavirus Resource Thread

Postby SriKumar » 04 May 2020 22:13

chola wrote:
Zynda wrote:Doing hot water sipping & stream inhalations daily (at least twice a day)...


..

Gunvor Cuomo pretty much confirmed explicitly yesterday what you were saying .....that NYC was hit badly because flights from Europe were not blocked or screened properly. the focus was on flights from China and for a whole month after that, when finally Europe flights were stopped.

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Re: Wuhan Coronavirus Resource Thread

Postby saip » 04 May 2020 22:15

Few years ago I was in China and our group had a vehicle and a guide. There were plenty of water bottles for us. What surprised me was they never thought to put a cooler in the vehicle. The result we all were drinking if we were lucky warm water (when the A/C in the vehicle was on) or even hot water at times. The guide told us they ALWAYS drink warm water. So nothing new about the Chinese drinking warm water. If drinking warm water prevents the infection they should not have gotten the infection in the first place. Another internet hoax.

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Re: Wuhan Coronavirus Resource Thread

Postby nvishal » 04 May 2020 22:21

About to hit 3000 cases per day any day now

Testing is mostly only being done on people with symptoms and asymptotic people who came in contact with the positive cases

People wearing masks are contracting it and I now believe they offer minimum protection. If you're an exempted person travelling daily then it is just a matter of time before you contract it. You'll probably never know you had it.

Actual cases are probably several times higher and many of them have already developed antibodies.

There is still no answer as to why the virus prefers to attack some bodies while it skips others altogether.

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Re: Wuhan Coronavirus Resource Thread

Postby schinnas » 04 May 2020 22:56

Stop this ignorant nonsense about not enough testing. It has been explained multiple times in this forum that India is testing adequately and uses valid statistical methods and random testing and monitoring death rates to validate infection rates.

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Re: Wuhan Coronavirus Resource Thread

Postby VickyAvinash » 04 May 2020 23:09

I work with a MNC and frequently travel across India. In Feb-March, I frequented to Mumbai and Jaipur regularly. Sometimes in middle of Feb, I got severe dry cough and acute pain in throat that lasted about 3 weeks. I got slight fever and took paracetamol. Ultimately, homeopathy medicine, ayurvedic Kaada and gargles with salt water helped me get over it. My wife also got it and so did my 8 year son. Wife was to recover first, followed by myself and son. This is all before I read about corona and took it seriously. I am now not sure what we contracted and waiting for the anti-body tests to be readily available for a self test. It has scared me pretty deep.

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Re: Wuhan Coronavirus Resource Thread

Postby saip » 05 May 2020 00:06

Masks are NOT for protecting you from getting infected. May be N95 masks will offer SOME protection to you from getting infected but not surgical masks. Masks are meant to stop you from SPREADING infection to others. When you are not wearing a mask your breath carries the virus if you are infected a few feet but if you are wearing a mask you breath (and the virus in case you are carrying) will stop in less than a foot. If everyone wears a mask and maintains social distance then I am sure the infection will drop significantly. Two days back I was in Walmart and I noticed half of the people were NOT wearing masks. Even educated people can behave idiotically. Now Costco has imposed masks for everyone if you want to enter.

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Re: Wuhan Coronavirus Resource Thread

Postby Raveen » 05 May 2020 00:29

VickyAvinash wrote:I work with a MNC and frequently travel across India. In Feb-March, I frequented to Mumbai and Jaipur regularly. Sometimes in middle of Feb, I got severe dry cough and acute pain in throat that lasted about 3 weeks. I got slight fever and took paracetamol. Ultimately, homeopathy medicine, ayurvedic Kaada and gargles with salt water helped me get over it. My wife also got it and so did my 8 year son. Wife was to recover first, followed by myself and son. This is all before I read about corona and took it seriously. I am now not sure what we contracted and waiting for the anti-body tests to be readily available for a self test. It has scared me pretty deep.



Umm homeopathy aka placebo? Glad that helps


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