Wuhan Coronavirus Resource Thread

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hanumadu
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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 02 Jun 2020 17:48

Has Maharashtra seen the peak? If this is the worst in MH, other Indian cities cannot be much worse off than Mumbai with the possible exception of West Bengal/Kolkota. Is it because the migrants left? According to reports, only a quarter of the migrants left. Keeping fingers crossed.

Image

Are strict social distancing rules being followed in Mumbai and other places in India? If restrictions are eased will the cases increase again? Especially as the temperatures go down.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 02 Jun 2020 18:28

Can somebody tell me at what rate the economy is functioning currently? 50%, 70% or 80% of normal?

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Re: Wuhan Coronavirus Resource Thread

Postby Shameek » 02 Jun 2020 19:37

hanumadu wrote:Are strict social distancing rules being followed in Mumbai and other places in India? If restrictions are eased will the cases increase again? Especially as the temperatures go down.


Definitely not in Pune. Most non Red zones look like life has gone back to normal. No social distancing, no masks and crowds building up in many areas.

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Re: Wuhan Coronavirus Resource Thread

Postby sajo » 02 Jun 2020 20:12

Shameek wrote:
Definitely not in Pune. Most non Red zones look like life has gone back to normal. No social distancing, no masks and crowds building up in many areas.


I agree it's not followed to a large extent in Pune. No social distancing, mask usage is still about 50% with hardly any use amongst the underprivileged strata. Traffic is now quite dense as well. Even post 9pm curfew is not followed or enforced at all. Domestic help is back in most places.
On the retail side everything seems to be normal saved for jacked up prices.
Pune stands at 6750 cases as of June1. Daily news reports of people succumbing to illnesses including Chinese virus due to lack of ambulances, and lack of hospital beds.

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Re: Wuhan Coronavirus Resource Thread

Postby Yagnasri » 02 Jun 2020 20:19

Entire MH state is left to Ram bharose by the political leadership. What can police and other authorities do in such a situation? The mercantile culture is too much ingrained in the minds of people in Mumbai and maybe even in Pune. It is very difficult to mobile and fight in this culture.

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Re: Wuhan Coronavirus Resource Thread

Postby Gyan » 02 Jun 2020 20:23

Lancet paper based on data "only" from Surgisphere

Surgisphere has 2 Employees

1st Employee is a former ***** star

2nd Employee is a fiction writer

And I kid you not. Google or Twitter search, what I said.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 02 Jun 2020 20:32

Shameek wrote:
hanumadu wrote:Are strict social distancing rules being followed in Mumbai and other places in India? If restrictions are eased will the cases increase again? Especially as the temperatures go down.


Definitely not in Pune. Most non Red zones look like life has gone back to normal. No social distancing, no masks and crowds building up in many areas.

I can understand people wanting to get back to business, but I can't fathom people not wearing masks.

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 02 Jun 2020 20:53

Wuhan tests nearly 10 million people, finds only 300 COVID-19 infections

Not posting the article. Anyways, seriously gotta hand it to the Chinese. Testing 10 Million people is no joke...its almost like testing entire BLR population.

How are we going about Anti-body tests?

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Re: Wuhan Coronavirus Resource Thread

Postby Krita » 03 Jun 2020 01:34

Zynda wrote:Wuhan tests nearly 10 million people, finds only 300 COVID-19 infections

Not posting the article. Anyways, seriously gotta hand it to the Chinese. Testing 10 Million people is no joke...its almost like testing entire BLR population.

How are we going about Anti-body tests?

Read somewhere that only 30% of pvt labs testing capacity is being utilised. One of the labs revealed that some of the state govts are restricting the tests to keep the number low. Since, they have limited beds in hospitals. Delhi is doing around 6000-7000 tests per day with a 23% prevalence rate.

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Re: Wuhan Coronavirus Resource Thread

Postby darshan » 03 Jun 2020 02:01

‘PRAANA’: IISc Team Successfully Completes Prototyping Of Indigenously Developed ICU-Grade Ventilator
https://swarajyamag.com/news-brief/praa ... ventilator
Built using a custom-designed pneumatic system controlled by a microprocessor, PRAANA ventilator uses proprietary algorithms and techniques to blend air and oxygen in the desired ratio, the institute said in a statement.

“It also has fine-grained control of patient-side respiratory parameters such as respiration rate, inspiration to expiration ratio, FiO2, and PEEP,” the statement added.

The PRAANA ventilator, which supports both invasive and non-invasive ventilation, uses only components made in India or easily available in the domestic supply chains.

Project PRAANA was started by IISc faculty members Gaurab Banerjee, Duvvuri Subrahmanyam, TV Prabhakar, and Pratikash Panda, Bangalore-based engineer Manas Pradhan, and retired IISc professor HS Jamadagni.

The team took about 35 days to go from the drawing board to a proof-of-concept system, and then a working prototype in another two weeks.

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Re: Wuhan Coronavirus Resource Thread

Postby Vivasvat » 03 Jun 2020 02:02

Gyan wrote:Lancet paper based on data "only" from Surgisphere
Surgisphere has 2 Employees
1st Employee is a former ***** star
2nd Employee is a fiction writer
And I kid you not. Google or Twitter search, what I said.

https://www.medpagetoday.com/infectiousdisease/covid19/86692
See the comments by Dr. OG

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 03 Jun 2020 15:07

Krita wrote:
Zynda wrote:Wuhan tests nearly 10 million people, finds only 300 COVID-19 infections

Not posting the article. Anyways, seriously gotta hand it to the Chinese. Testing 10 Million people is no joke...its almost like testing entire BLR population.

How are we going about Anti-body tests?

Read somewhere that only 30% of pvt labs testing capacity is being utilised. One of the labs revealed that some of the state govts are restricting the tests to keep the number low. Since, they have limited beds in hospitals. Delhi is doing around 6000-7000 tests per day with a 23% prevalence rate.


Only NABL certified labs are allowed to do test at present.. Very few labs are NABL certified.. It appears that govt is intentionally discouraging use of antibody kit..

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Re: Wuhan Coronavirus Resource Thread

Postby kvraghav » 03 Jun 2020 15:21

Zynda wrote:Wuhan tests nearly 10 million people, finds only 300 COVID-19 infections

Not posting the article. Anyways, seriously gotta hand it to the Chinese. Testing 10 Million people is no joke...its almost like testing entire BLR population.

How are we going about Anti-body tests?

These 10 million tests were rapid tests or RT-PCR?

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Re: Wuhan Coronavirus Resource Thread

Postby chola » 03 Jun 2020 15:52

I read reports that Chinis spent $120M for those tests in Wuhan. A pretty big waste of money for an area that's been locked down for five months and which results they already know through hospital data and tracking. A chinese person can't even go to a neighbor convenient store without his bio-metrics being taken and tracked by Big Brother Xi.

So why waste that kind of money in an economy that's already depressed?

Actually Wuhan being depressed is exactly the reason why they needed to do this. Fear has kept people from engaging in normal activity. Fear has people saving extraordinary amounts for security instead of spending to boost the economy. Fear has Wuhan being treated like a leper by the rest of Cheen so that economic activities bypass it.

The only way to get past that fear is to test everyone. And they have better be sure that it doesn't break out a second time or even the rest of Cheen will treat it as a Chernobyl.

Something to ponder as India, especially Mumbai, recovers.

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Re: Wuhan Coronavirus Resource Thread

Postby Lisa » 03 Jun 2020 18:28

It would be hard to make this up.

Governments and WHO changed Covid-19 policy based on suspect data from tiny US company

https://www.theguardian.com/world/2020/ ... hloroquine

The Guardian’s investigation has found:

A search of publicly available material suggests several of Surgisphere’s employees have little or no data or scientific background.

An employee listed as a science editor appears to be a science fiction author and fantasy artist. Another employee listed as a marketing executive is an adult model and events hostess.

The company’s LinkedIn page has fewer than 100 followers and last week listed just six employees. This was changed to three employees as of Wednesday.
While Surgisphere claims to run one of the largest and fastest hospital databases in the world, it has almost no online presence. Its Twitter handle has fewer than 170 followers, with no posts between October 2017 and March 2020.

Until Monday, the “get in touch” link on Surgisphere’s homepage redirected to a WordPress template for a cryptocurrency website, raising questions about how hospitals could easily contact the company to join its database.

Desai has been named in three medical malpractice suits, unrelated to the Surgisphere database. In an interview with the Scientist, Desai previously described the allegations as “unfounded”.

In 2008, Desai launched a crowdfunding campaign on the website indiegogo promoting a wearable “next generation human augmentation device that can help you achieve what you never thought was possible”. The device never came to fruition.

Desai’s Wikipedia page has been deleted following questions about Surgisphere and his history.

also

It is not the first time Desai has launched projects with ambitious claims. In 2008, he launched a crowdfunding campaign on the website indiegogo promoting a “next generation human augmentation device” called Neurodynamics Flow, which he said “can help you achieve what you never thought was possible”.

“With its sophisticated programming, optimal neural induction points, and tried and true results, Neurodynamics Flow allows you to rise to the peak of human evolution,” the description said. The device raised a few hundred dollars, and never eventuated. :roll: :roll:

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Re: Wuhan Coronavirus Resource Thread

Postby darshan » 03 Jun 2020 18:38

chola wrote:I read reports that Chinis spent $120M for those tests in Wuhan.

One can also look at it from the different perspective. May be they were busted or over produced lab materials. Nothing by Chinese can be trusted. May be it's 300 or may be it's instilling false sense of superiority to make CCP great again. It's a civilization that has never shied away from killing it's own to achieve superficial things.

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 Jun 2020 19:39

Image
Virus weakening

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 Jun 2020 19:41

Is Coronavirus Weakening? https://www.voanews.com/covid-19-pandem ... -weakening

A study conducted by a major hospital in Milan, Italy, has found that the viral load present in people who now test positive for the coronavirus is decreasing, suggesting the infection may be weakening, according to doctors, whose findings have been greeted with skepticism.

Alberto Zangrillo, head of Milan's San Raffaele Hospital, said the coronavirus might be becoming less lethal and that those who have been recently infected have weaker symptoms than two months ago. “The swabs performed over the last 10 days show a viral load in quantitative terms that was absolutely infinitesimal compared to the ones carried out a month or two months ago,” Zangrillo, a physician to former Prime Minister Silvio Berlusconi, told Italy’s public broadcaster, RAI.

The president of the scientific body advising the government on the pandemic says he is “baffled” by the claim. Italy has the third-highest coronavirus death toll in the world, with 33,475 people dying since the outbreak emerged it February, according to Italy’s Civil Protection agency. After a strict national lockdown, which is now being eased, infections and fatalities have fallen steadily.

Italian government officials are urging caution about the claim of the virus turning less lethal, warning it could confuse Italians. “We should instead invite Italians to maintain the maximum caution, maintain physical distancing, avoid large groups, to frequently wash their hands and to wear masks,” Sandra Zampa, an undersecretary at the health ministry, said in a statement.

Epidemiologists outside Italy are skeptical.

Oscar MacLean, of the MRC-University of Glasgow Center for Virus Research in Scotland, said, “These claims are not supported by anything in the scientific literature, and also seem fairly implausible on genetic grounds. The vast majority of SARS-CoV-2 mutations are extremely rare, and so whilst some infections may be attenuated by certain mutations, they are highly unlikely to be common enough to alter the nature of the virus at a national or global level.”

COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

MacLean added, “Making these claims on the basis of anecdotal observations from swab tests is dangerous. Whilst weakening of the virus through mutations is theoretically possible, it is not something we should expect, and any claims of this nature would need to be verified in a more systematic way.”

Nonetheless, in the face of a media storm about the findings, doctors and researchers at San Raffaele Hospital are standing firm. Massimo Clementi, director of the Microbiology and Virology Laboratory at the hospital, says an analysis of 200 patients suggests the virus has “enormously weakened.”

Skeptics question Zangrillo’s motivation. He has clashed with critics for saying the fear of a second wave of coronavirus infections is misplaced, according to Italian newspapers.

“We've got to get back to being a normal country. Someone has to take responsibility for terrorizing the country,” he said Sunday. He noted previous epidemics such as MERS and SARS "petered out by themselves.” He also said, “We've got to be wary, yes, but not kill ourselves unnecessarily. Our wards are emptying out.”

Currently, close to 6,400 people are hospitalized with 435 people in intensive care in Italy. More than 32,250 people are self-isolating at home with symptoms of the virus, according to the Civil Protection agency.

San Raffaele Hospital is also receiving support from some other experts. The head of the infectious diseases clinic at San Martino hospital in the city of Genoa, Matteo Bassetti, told Italy’s ANSA news agency he is seeing the same trend. “The strength the virus had two months ago is not the same strength it has today,” he said, adding, “It is clear that today the COVID-19 disease is different.”

Franco Locatelli, the president of the National Health Council which advises the Italian government, said he could only express “great surprise and absolute bafflement” at the claims.

“You just need to look at the number of new positive cases confirmed every day to see the persistent circulation of the virus in Italy," he told ANSA.

Allan Cheng, an infectious diseases physician at The Alfred hospital in Melbourne, Australia, said, “We haven’t noticed any difference in viral loads in people we’ve tested.”

He told Australian media, “We’d be pretty surprised, if that was the case. This is not a virus that mutates all that quickly.”

He said the difference in viral loads the Milan hospital is seeing could well be explained by an increase in their testing of people who have not fallen very sick from the coronavirus.

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 Jun 2020 19:42

SARS CoV 1 also weakened and disappeared before vaccine arrived.

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Re: Wuhan Coronavirus Resource Thread

Postby arshyam » 03 Jun 2020 19:46

^^ Did a vaccine actually arrive?

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Re: Wuhan Coronavirus Resource Thread

Postby Raveen » 03 Jun 2020 20:34

arshyam wrote:^^ Did a vaccine actually arrive?


No, becasue it disappeared, so did the research $

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Re: Wuhan Coronavirus Resource Thread

Postby nandakumar » 03 Jun 2020 20:46

For the last two days I have been reading up the case fatality reports of individual cases as released by the Tamilnadu government. What struck me was most of the fatalities were those that died within 2 or 3 days of admission. In one or two cases it was even one day. Of course the number of deaths are still low. So that is a good news. But the fact that death is within a few days of admission is disconcerting. Is this something unique to Tamilnadu or this is the case across the country?

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Re: Wuhan Coronavirus Resource Thread

Postby srin » 03 Jun 2020 20:58

Are only Govt hospitals treating infected patients ? Or are private hospitals also doing it ?

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 Jun 2020 21:05

arshyam wrote:^^ Did a vaccine actually arrive?

Coronavirus before 2019, caused 2 epidemics: SARS Cov1 (2002) and MERS (2012). They were virulent diseases with significant mortality hence noticed easily and patients isolated. They quickly disappeared in one year time.
Vaccines were attempted but they need to be tried on large number of subjects which were not available so carrying on with development was no longer feasible.
Some scientists carried on working, the current Oxford vaccine is actually using suitcase which was meant for SARS Cov 1.
But funds dried up as pharma companies & govt were no longer interested in a vaccine for a disease not around. Though sporadic outbreaks have been reported at very small scale.

COVID-19 Data Dives: Why Don't We Have a Vaccine for SARS or MERS? https://www.medscape.com/viewarticle/931226

It is easy to point to the fact that we don't have licensed vaccines for severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), or HIV/AIDS as reasons to be discouraged about COVID-19. These diseases have been around longer than COVID-19. In the case of HIV/AIDS, much longer. Is there reason to be worried?

Let me attempt to provide some perspective and even a small dose of optimism. We are not in the same situation here.

First, HIV is a uniquely challenging virus, and it is possible that we may never have an HIV vaccine. HIV attacks the host immune system, making it difficult to design an effective vaccine. It also mutates rapidly, diversifying within a person over the course of their infection. Viral diversity within a single person has been shown to be comparable to viral diversity of influenza across the globe. In comparison, SARS-CoV-2 mutates even more slowly than seasonal influenza, making it a more stable target for vaccines.

Next, SARS caused an explosive outbreak in 2003 (Figure 1). Fortunately, that outbreak was contained, in part because SARS-CoV caused severe illness that was less likely to be missed during tracing, and there was no presymptomatic or asymptomatic transmission. After being contained in 2003, there have been no SARS outbreaks since.

While several SARS vaccine candidates were developed, funding dried up to test them further. In addition, there has been no clear pathway for testing the efficacy of SARS vaccine and getting it approved for use. How can we determine whether a vaccine prevents SARS if there is no SARS to prevent? Thus, these candidates have been stalled at earlier stages of development.

Finally, MERS was first reported in 2012. Since then, there have been regular "spillover" events whereby the virus jumps from the camel reservoir into humans and may transmit directly between humans. Some early MERS outbreaks were explosive, including an exported outbreak in South Korea in 2015. But Saudi Arabia, where the majority of transmission occurs, has made great improvements to its infection control procedures to prevent hospital spread. As a result, recent outbreaks have been much smaller .

Organizations like the Coalition for Epidemic Preparedness Innovations (CEPI) have been funding research for MERS vaccine candidates, but one persistent challenge is identifying strategies to evaluate the efficacy of these vaccines. Along with other researchers involved in the WHO R&D Blueprint, we have discussed potential strategies for a MERS vaccine efficacy trial. But given the relatively low incidence even in high-risk groups (camel workers, their families, healthcare workers), trials could need 100,000-plus participants, which isn't feasible. As a result, there still isn't a clear path forward for testing a vaccine and getting it approved by regulators.

Of course we all would be better off with effective SARS, MERS, and HIV/AIDS vaccines. In particular, if we had licensed SARS and MERS vaccines, they could be modified for COVID-19. Indeed, many of these candidates were brought back off the shelf for exactly this purpose. But the fact that approved vaccines for these diseases do not exist reflects other challenges in their development as much as anything else. For COVID-19, with widespread transmission and active funding, we should expect large trials to soon begin testing the many vaccine candidates being pursued in parallel. So if one or more of them works, we should be able to figure this out quickly.

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 03 Jun 2020 21:08

Scientists were close to a coronavirus vaccine years ago. Then the money dried up https://www.nbcnews.com/health/health-c ... d-n1150091

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Re: Wuhan Coronavirus Resource Thread

Postby nandakumar » 03 Jun 2020 21:57

srin wrote:Are only Govt hospitals treating infected patients ? Or are private hospitals also doing it ?

I think the reports of case fatalities are from Govt hospitals. There are private hospitals too that are treating Covid patients (Apollo hospitalin Chennaifor instance). But what happens is when a patient's situation deteriorates he/she is transferred to a Government hospital. But not all fatalities are last minute transfer from private hospitals.

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Re: Wuhan Coronavirus Resource Thread

Postby chetak » 04 Jun 2020 01:58

WHO To Resume Hydroxychloroquine’s Coronavirus Trials After Study Based On Which It Was Stopped Turns Out To Be Dubious https://swarajyamag.com/insta/who-to-resume-hydroxychloroquines-coronavirus-trials-after-study-based-on-which-it-was-stopped-turns-out-to-be-dubious via @swarajyamag

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Re: Wuhan Coronavirus Resource Thread

Postby chetak » 04 Jun 2020 02:02

Dr Praveen Patil@5Forty3·9h

BTW, India has quietly moved in to being the fourth most tested country in the world for COVID-19, behind US, Russia and UK (all 20th century superpowers with top notch, experienced healthcare systems).

Big Lesson: the impossible is possible even in a chaotic country like India!

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Re: Wuhan Coronavirus Resource Thread

Postby vijayk » 04 Jun 2020 03:20

https://timesofindia.indiatimes.com/ind ... 186055.cms
Did the virus enter India in November-December?

.
Using a scientific technique called "time to most recent common ancestor", MRCA, scientists estimated the viral strain now circulating in Telangana and other states had originated between November 26 and December 25, the median being December 11

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Re: Wuhan Coronavirus Resource Thread

Postby Gerard » 04 Jun 2020 04:22


IndraD
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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 04 Jun 2020 04:32

Ex British Intel chief says Wuhan virus man made based on research
https://t.co/K4PS37XMQf

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Re: Wuhan Coronavirus Resource Thread

Postby darshan » 04 Jun 2020 05:15

vijayk wrote:https://timesofindia.indiatimes.com/india/did-the-virus-enter-india-in-november-december/articleshow/76186055.cms
Did the virus enter India in November-December?

.
Using a scientific technique called "time to most recent common ancestor", MRCA, scientists estimated the viral strain now circulating in Telangana and other states had originated between November 26 and December 25, the median being December 11


Thanksgiving to Christmas tourist trips.
Tons of Indian students in China.


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Re: Wuhan Coronavirus Resource Thread

Postby vijayk » 04 Jun 2020 22:00

kit wrote:https://timesofindia.indiatimes.com/india/indias-urban-covid-19-outbreak-is-morphing-into-a-rural-health-crisis/articleshow/76197680.cms


Rural parts of India have begun to see a surge in novel corona virus infections, as millions of migrant workers returning from big cities and industrial hubs bring the virus home with them

Read more at:
http://timesofindia.indiatimes.com/arti ... aign=cppst ..


Image




Barkha, rNDTV, PeePeeCee , NYT achieved what they wanted ...

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Re: Wuhan Coronavirus Resource Thread

Postby mukkan » 05 Jun 2020 04:31

The Lancet retracts study on hydroxychloroquine and chloroquine

https://www.thelancet.com/lancet/articl ... 3620313246

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Re: Wuhan Coronavirus Resource Thread

Postby vijayk » 05 Jun 2020 06:13

mukkan wrote:The Lancet retracts study on hydroxychloroquine and chloroquine

https://www.thelancet.com/lancet/articl ... 3620313246


https://www.wsj.com/articles/authors-re ... 1591299329

These ba$tards needs to be taken down, mocked and laughed at.

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Re: Wuhan Coronavirus Resource Thread

Postby DavidD » 05 Jun 2020 09:00

mukkan wrote:The Lancet retracts study on hydroxychloroquine and chloroquine

https://www.thelancet.com/lancet/articl ... 3620313246


Good, I don't think I know a of a single physician who didn't raise his eyebrows at that study.

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Re: Wuhan Coronavirus Resource Thread

Postby DavidD » 05 Jun 2020 09:01

anmol wrote:
DavidD wrote:Anyone has a link to the actual study? I couldn't find it on a google search, just articles about it.
Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19
http://www.ijmr.org.in/temp/IndianJMedRes000-4255589_114915.pdf

http://www.ijmr.org.in/downloadpdf.asp?id=285520;type=2


Thanks, but both links just say "page not found" for me, not sure why. Maybe it's locked by region?

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Re: Wuhan Coronavirus Resource Thread

Postby Aarvee » 05 Jun 2020 11:19

DavidD wrote:
anmol wrote:


Thanks, but both links just say "page not found" for me, not sure why. Maybe it's locked by region?


Just google the article title sir. The article comes up.
Edit: http://www.ijmr.org.in/preprintarticle.asp?id=285520;type=0

Abstract:
Background & objectives: Healthcare workers (HCWs) are at an elevated risk of contracting COVID-19. While intense occupational exposure associated with aerosol-generating procedures underlines the necessity of using personal protective equipment (PPE) by HCWs, high-transmission efficiency of the causative agent [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] could also lead to infections beyond such settings. Hydroxychloroquine (HCQ), a repurposed antimalarial drug, was empirically recommended as prophylaxis by the National COVID-19 Task Force in India to cover such added risk. Against this background, the current investigation was carried out to identify the factors associated with SARS-CoV-2 infection among HCWs in the country. Methods: A case-control design was adopted and participants were randomly drawn from the countrywide COVID-19 testing data portal maintained by the ICMR. The test results and contact details of HCWs, diagnosed as positive (cases) or negative (controls) for SARS-CoV-2 using real-time reverse transcription-polymerase chain reaction (qRT-PCR), were available from this database. A 20-item brief-questionnaire elicited information on place of work, procedures conducted and use of PPE. Results : Compared to controls, cases were slightly older (34.7 vs. 33.5 yr) and had more males (58 vs. 50%). In multivariate analyses, HCWs performing endotracheal intubation had higher odds of being SARS-CoV-2 infected [adjusted odds ratio (AOR): 4.33, 95% confidence interval (CI): 1.16-16.07]. Consumption of four or more maintenance doses of HCQ was associated with a significant decline in the odds of getting infected (AOR: 0.44; 95% CI: 0.22-0.88); a dose-response relationship existed between frequency of exposure to HCQ and such reductions (χ2 for trend=48.88; P<0.001). In addition, the use of PPE was independently associated with the reduction in odds of getting infected with SARS-CoV-2. Interpretations & conclusions: Until results of clinical trials for HCQ prophylaxis become available, this study provides actionable information for policymakers to protect HCWs at the forefront of COVID-19 response. The public health message of sustained intake of HCQ prophylaxis as well as appropriate PPE use need to be considered in conjunction with risk homoeostasis operating at individual levels.
Last edited by Aarvee on 05 Jun 2020 11:43, edited 1 time in total.

Nihat
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Re: Wuhan Coronavirus Resource Thread

Postby Nihat » 05 Jun 2020 11:39

Even I'm unable to find the study and it would be very beneficial for my work with MOHFW. It would be great if some kind soul would share the same in case they have access

On the virus front though, we seem to be following a very confused policy. We are registering record cases every single day and now even on the rural areas and yet the single minded focus seems to be on opening up.

I understand that we need to cater to economic concerns but at the very least we must have at the very least fully locked down the 13 districts which accounted for over 70% of the infections.

Now that community transmission is well and truly underway, it is to an extent beyond our control. The handling of this pandemic has been disappointing after b lockdown 2.0.


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