Wuhan Coronavirus Resource Thread

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sanjaykumar
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Re: Wuhan Coronavirus Resource Thread

Post by sanjaykumar »

Italy was similarly devastated. Same reason as previously discussed.
Karan M
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Re: Wuhan Coronavirus Resource Thread

Post by Karan M »

Reference O2 demands and cost of plant etc.

162 PSA plants including 7 years worth of maintenance after 3 year warranty cost us Rs 201. 54 Cr. So 1.24 Cr per plant. How shoddy state level execution is, can be judged from the fact that after this was cleared in December, only 33 plants have come up. Many hospitals didn't bother to set them up. Cumulative capacity was 86, 940 Ltrs per minute. CV patients are put at 2/5/7/10 Ltrs/minute. So at the higher flow rate, this was equivalent to assisting around 8694 patients. Of course some may require far more but you get the idea.

Now the plan has been extended to adding 551 more of these, covering all districts in the country. And it's funding has been cleared. And this time there will be more focus on getting things done, as versus funding alone. The overall capacity will now be at around 38,000 patients per day. With India's active cases at around 3L in the surge per day, yesterday, even if 10% need O2, we would be hitting capacity. Of course additional capacity already exists in the public and pvt sector too, but a lot of that is industries diverting their supply.

Net, these PSA can be an addition to the infra but we need more capacity build up in the industrial pvt sector, which is sustainable via exports too. That way additional slack in the system can be maintained above and beyond this vital purchase.
Karan M
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Re: Wuhan Coronavirus Resource Thread

Post by Karan M »

I trust people have seen the news from today.

https://www.google.com/amp/s/www.livemi ... 69571.html

"United States has identified sources of specific raw material urgently required for Indian manufacture of Covishield vaccine that will immediately be made available for India," said US NSA Jake Sullivan to NSA Ajit Doval.


Trust this settles the matter. As I had surmised in a prior post, the USG and GOI were in back channel talks to solve this issue, hence SII was not publicly flagging the topic. However when things didn't move fast enough, his operations folk did speak up about it.

Note, as a license manufacturer SII is particularly dependent on a standard BOM as he can't change it due to the fact he doesn't have the inhouse R&D plus there are regulatory issues involved.

We really need a massive Aatmanirbhar program for pharma raw materials for the vaccine sub-sector too. As the above issue still exists in some form or the other for all vaccines.

This is a very low hanging fruit. Operation Warp Speed for instance allocated around $300-400Mn for the more critical raw materials, out of an overall $10 Bn program. Even half of that, by Indian standards, would go a long way in terms of indigenization and localisation.
Karan M wrote:
sohamn wrote:

He never claimed supplies for Covishield was an issue, show me one interview of his which indicated to this. Always, he said the supply issue constrained covovax production - which is significantly more superior to covishield.

Covishield is based on UK tech and doesn't require the kind of filters/bags that Novavax requires, being a US tech. He mainly got burned by the fire in his new factory and hence the delay in ramping up production of covishield. Also, lack of free capital blocked sourcing raw materials as well.
Just go up this very thread and see interviews from SII officials themselves that they needed US supplies.
Economist wrote:Yet this ambition is at risk from American export controls on raw materials and equipment. Production lines in India, making at least 160m doses of covid vaccine a month, will come to a halt in the coming weeks unless America supplies 37 critical items.

On April 16th, Adar Poonawalla, the chief executive of the Serum Institute of India (SII), the world’s biggest vaccine-maker, put out a tweet begging President Joe Biden to “lift the embargo of raw material exports out of the US...Your administration has the details”. Suresh Jadhav, SII’s executive director, says “we are absolutely concerned,” and that in the next four to six weeks the production of two vaccines will be affected: AstraZeneca’s, of which SII makes 100m doses a month, and Novavax’s, of which it expects to make 60m-70m doses a month. SII says it first alerted the American government to the impending problem two months ago.
I dont think you understand the issue. There is no UK tech or US tech in this business, beyond core IP regarding process and how the vaccine itself is designed and created. Supplies for consumables come from firms worldwide many of which are HQ in the US or with significant operations in the US and are hence subject to their laws and regulations. This is the same case in most industries where the US exercises disproportionate power thanks to its economic and military heft, backed up with laws which enable it to exercise that heft brazenly.
Karan M wrote:
Suraj wrote: It's never been an issue, in my view. AZ is not an American company. It is manufactured in US, EU, India and Japan at the very least. Japan has an AZ stockpile because their regulator has sat on their behinds and not approved it. With such a diverse production setup, one country cannot easily constrain it - SII can switch to another source.

The more egregious problem with US and AZ is that US produced - according to multiple references - over 50m doses of AZ and has not used it domestically, not approved it domestically, and refuses to export it to those who need it. DaiIchi started AZ production in Japan in March but the Japan govt has not approved it.
The articles I posted prior indicate it was an issue. We had a senior guy from SII making the case. IMO there have been efforts behind the scenes to secure the supplies likely with GOI assistance.

SII can't just switch suppliers easily. That comes with a regulatory and compliance burden which Adar will need Oxford/AZ's help for. BB can do this far more easily as it owns the IP, does R&D plus manufacturing and also, as it has ICMRs support, they are far more involved in the process enabling BB to cut the red tape. For instance, their choice of Adjuvant was because it too had secondary efforts in terms of immune response. When they changed it to a new one, they'd have to take that into consideration and also get the buy-in from regulatory authorities who cleared it based on the earlier supply chain.

Agree with you about wasting AZ doses. Stupid behavior.
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Re: Wuhan Coronavirus Resource Thread

Post by Mort Walker »

^^^Thanks Karan.
Trust this settles the matter. Note, as a license manufacturer SII is particularly dependent on a standard BOM as he can't change it due to the fact he doesn't have the inhouse R&D plus there are regulatory issues involved.

We really need a massive Aatmanirbhar program for pharma raw materials for the vaccine sub-sector too. As the above issue still exists in some form or the other for all vaccines.

This is a very low hanging fruit. Operation Warp Speed for instance allocated around $300-400Mn for the more critical raw materials, out of an overall $10 Bn program. Even half of that, by Indian standards, would go a long way in terms of indigenization and localisation.
Just like 1998 after Pokhran-II, the US placed sanctions on India, and the NDA government released the shackles on the economy. The same will happen here.
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Re: Wuhan Coronavirus Resource Thread

Post by Cyrano »

In this covid game, when things are going well, you get to see mostly lagging indicators and downward trends which has lulled people and govts all over into complacency. By the time the trend reverses and you are able to plot leading indicators and draw peaks and project case loads, its too late to arrest the trend.

Do all pademics unfold this way, I dont know.

By Feb, people were starved for normalcy after nearly a year of hardships, isolation and couldn't hold it any longer. Heck my own extended family with a bunch of doctors organised a 100+ people engagement ceremony in Feb, flying in people from across India, while as HCWs they just got vaccinated. They are sensible people but they still did it. Thankfully and luckily no one reported infected at or after the event.

As confidence returned, another bunch of 30 ppl went to Thirupathi in March but cut short the 5 day trip to 3 days and returned early when covid cases were reported in Thirumala. A very close shave, again luckily no one reported infection after that trip.

Two weeks later we started seeing huge spikes in April. Leading indicators were leading us to a disaster, like waking up in free fall.

I'm sure lots of such things happened all over India. Even Govt joined in with election rallys, allowed crowds in cricket matches etc etc.

Lesson learnt, price to pay will be hard and tragic for many, but will hopefully vaccinate us against future complacency. Time to look forward and deal with the crisis and vaccinate as many as quickly as we can.
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Re: Wuhan Coronavirus Resource Thread

Post by Cyrano »

To give another perspective, France has not been able to analyse the chains of transmission despite just 7 crore population and here also cases climbed up in March and April, currently plateauing at about 30k/day since 3 weeks. An extended peak.

French Gov has tried multiple mesures like semi lockdown, night curfew, schools open, partially closed, fully closed etc etc but cases are still coming. Sadly faster than vaccine doses.

We all have to grunt and bear it, do our bit, stay sane and try and be generous to those needier than ourselves.
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Re: Wuhan Coronavirus Resource Thread

Post by Suraj »

India’s massive COVID surge puzzles scientists
Studies that tested for SARS-CoV-2 antibodies — an indicator of past infection — in December and January estimated that more than 50% of the population in some areas of India’s large cities had already been exposed to the virus, which should have conferred some immunity, says Manoj Murhekar, an epidemiologist at the National Institute of Epidemiology in Chennai, who led the work. The studies also suggested that, nationally, some 271 million people had been infected1 — about one-fifth of India’s population of 1.4 billion.

These figures made some researchers optimistic that the next stage of the pandemic would be less severe, says Ramanan Laxminarayan, an epidemiologist in Princeton University, New Jersey, who is based in New Delhi. But the latest eruption of COVID-19 is forcing them to rethink.

One explanation might be that the first wave primarily hit the urban poor. Antibody studies might not have been representative of the entire population and potentially overestimated exposure in other groups, he says.
The antibody data did not reflect the uneven spread of the virus, agrees Gagandeep Kang, a virologist at the Christian Medical College in Vellore, India. “The virus may be getting into populations that were previously able to protect themselves,” she says. That could include wealthier urban communities, in which people isolated during the first wave but had started mingling by the second.
Udwadia has anecdotally observed that entire households are now getting infected — unlike in the first wave of COVID-19, when single individuals would test positive. He attributes this to the presence of more-infectious variants. “If one person in the family has it, I can guarantee that everyone in the family has it,” he says.
B.1.617 has drawn attention because it contains two mutations that have been linked to increased transmissibility and an ability to evade immune protection. It has now been detected in 20 other countries. Laboratories in India are trying to culture it to test how fast it replicates, and whether blood from vaccinated individuals can block infection, says Jameel.
With cases declining after last September’s peak, “there was a public narrative that India had conquered COVID-19”, says Laxminarayan. In recent months, large crowds have gathered indoors and outdoors for political rallies, religious celebrations and weddings.

The nationwide vaccination campaign, which kicked off in January, might even have contributed to an uptick in cases, if it caused people to ease public-health measures. “The arrival of the vaccine put everyone into a relaxed mood,” says Laxminarayan.
There were questions asking why vaccination started 'slowly' with only HCWs first - it was to ensure HCWs were immune before helping others. In my view, this wave would have hit in February if we tried to vaccinate everyone back then, causing people to let their guard down before vaccinations really got started.
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Re: Wuhan Coronavirus Resource Thread

Post by IndraD »

https://www.nytimes.com/2021/04/25/worl ... covid.html
US resumes vaccine raw materials supply for Oxford to India
Cyrano
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Re: Wuhan Coronavirus Resource Thread

Post by Cyrano »

My own anecdotal family experience posted above corroborates what Suraj posted right after.

My GP here says there is no mystery, dont go out into crowded places, wear a proper mask properly, wash hands, keep distance, sanitise often used surfaces. If some people dont follow some of these, virus spreads. Only full vaccination of 14+ population can being this under control
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Re: Wuhan Coronavirus Resource Thread

Post by S_Madhukar »

Hate to say it but our public had this coming... we have overconfidence almost arrogance in not following rules... the PM on TV wears a mask at all times, some other mugs like Khujli often don’t wear it as if they can’t cause any transmissions... it is a reflection on our society.. my 70+ parents in the city were complaining of crowds not wearing masks or wearing them on the mouth.... bhaajiwalas saying corona Gaya! Back in January, February The government was also a bit complacent, heck we can’t sustain prolonged lockdowns and rules... how do we square the circle like the East Asian countries could.. the only way now is to get a vaccine dose in all cities first, may be even have martial law and execute vaccinations at scale while having lockdowns in other places... mind boggling exercise this will be
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Re: Wuhan Coronavirus Resource Thread

Post by srai »

Cyrano wrote:My own anecdotal family experience posted above corroborates what Suraj posted right after.

My GP here says there is no mystery, dont go out into crowded places, wear a proper mask properly, wash hands, keep distance, sanitise often used surfaces. If some people dont follow some of these, virus spreads. Only full vaccination of 14+ population can being this under control
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Re: Wuhan Coronavirus Resource Thread

Post by srai »

Tanaji wrote:...

Sraiji,

The 24 lakh thing , is that an O2 concentrator or a system that delivers proper 99.99% oxygen which is then down mixed to whatever level the patient required? I find it hard to believe that medical grade can be got in 24 lakhs using either cryogenic or pressure swing adsorption methods.
Karan answered your question.
...

162 PSA plants including 7 years worth of maintenance after 3 year warranty cost us Rs 201.54 Cr. So 1.24 Cr per plant.

...
Seems very affordable for hospitals to possess one or at least co-op into one.
srai
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Re: Wuhan Coronavirus Resource Thread

Post by srai »

Great post Karan. +1

Karan M wrote:...

CV patients are put at 2/5/7/10 Ltrs/minute. ... Of course some may require far more but you get the idea.

...
The modified Tejas OBOGS on offer from DRDO can output 1000 liters per minute according to that Ajay Shukla’s article. Sounds like it may be a scaled up version.

Few OBOGS per facility seems quite sufficient especially for the pop-up COVID-19 treatment centers (w/ 250-1000 patients capacity). Perhaps majority of the hospitals in their emergency/ICU wards should have one!
Last edited by srai on 26 Apr 2021 06:27, edited 1 time in total.
Mort Walker
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Re: Wuhan Coronavirus Resource Thread

Post by Mort Walker »

Suraj,

Of the 22.3 million who have received both doses of vaccination:

1. Does this cover all HCW and FLW?
2. Of the FLW, does this include all of the Indian armed services and security units within the Home Ministry?
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Re: Wuhan Coronavirus Resource Thread

Post by arshyam »

Not Suraj, but here's one answer:

90-95% of Indian Army vaccinated with first COVID dose, say officials
Approximately 50 to 55% of the forces have been vaccinated with the 2nd dose as well.
Not sure if the above includes IAF and IN - the latter might be the last to complete, given their current deployments at sea, and they wouldn't risk vaccinating all sailors on active deployment.
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Re: Wuhan Coronavirus Resource Thread

Post by DrRatnadip »

Tanaji wrote:I think India should put more effort in sequencing of the virus to identify the various mutants floating around. Time and again people are saying they have no clue where they got infected from. In wave 1 we did not see the ramp up so quickly and people were more relaxed then.

More efforts need to be put in ramping up the sequencing of positive samples...

Sraiji,

The 24 lakh thing , is that an O2 concentrator or a system that delivers proper 99.99% oxygen which is then down mixed to whatever level the patient required? I find it hard to believe that medical grade can be got in 24 lakhs using either cryogenic or pressure swing adsorption methods.
Plant I quoted delivers medical grade oxygen through central oxygen system.. It cant refill cylinders to destribute or store.. Plant becomes more economical as capacity increases..
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Re: Wuhan Coronavirus Resource Thread

Post by pgbhat »

Raja wrote:That is a massive failure in understanding how society and humans work.

Why do we need any fines or rules? If everyone just did what they were supposed to do, we would be a superpower in 10 years. So simple.
I chuckled. This is so true. Have some relatives whose families are infected completely and are under treatment, thankfully at home. They suspect it happened because of one of the folks took a crowded metro to work because of transport strike. It is thankfully not severe just because most of the elderly folks were vaccinated.
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Re: Wuhan Coronavirus Resource Thread

Post by pgbhat »

DrRatnadip wrote: Sraiji,

Plant I quoted delivers medical grade oxygen through central oxygen system.. It cant refill cylinders to destribute or store.. Plant becomes more economical as capacity increases..
Doctor,

Do you have a recommendation for new mothers and mothers-to-be on vaccination? I understand that some other countries recommend vaccination for this group, India does not. Is it time to revisit the recommendation?
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Re: Wuhan Coronavirus Resource Thread

Post by Mort Walker »

arshyam wrote:Not Suraj, but here's one answer:

90-95% of Indian Army vaccinated with first COVID dose, say officials
Approximately 50 to 55% of the forces have been vaccinated with the 2nd dose as well.
Not sure if the above includes IAF and IN - the latter might be the last to complete, given their current deployments at sea, and they wouldn't risk vaccinating all sailors on active deployment.
Thanks!
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Re: Wuhan Coronavirus Resource Thread

Post by Manish_P »

srai wrote:..

The modified Tejas OBOGS on offer from DRDO can output 1000 liters per minute according to that Ajay Shukla’s article. Sounds like it may be a scaled up version.

...
Noob question to the Gurus. Does the Tejas OBOGs system have greater output at ground level (as compared to the cruise altitude of the fighter jet) due to higher air density at ground level ?
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Re: Wuhan Coronavirus Resource Thread

Post by Thakur_B »

Went for second covid test today to get a negative report for resuming office having previously been positive with mild pneumonia. Reached hospital at 8 AM to avoid long qeue, they told me to come back tomorrow 7 AM as they have already distributed tokens for the testing capacity for the day. Same for another test facility. Had to go to third facility to get tested. From the number of people in front of me, it looks like it will take whole day. This is for private testing facilities in Delhi. The government test facilities would be overwhelmed as well.
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Re: Wuhan Coronavirus Resource Thread

Post by Suraj »

arshyam answered it for me. The easiest way to track HCW/FLW 2nd dose coverage is the latest PIB data: https://www.pib.gov.in/PressReleasePage ... ID=1713853

HCW: 6m of 9.3m fully covered
FLW: 6.3m of 11.9m fully covered.
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Re: Wuhan Coronavirus Resource Thread

Post by darshan »

So far only Yogi has moved towards taking steps against spread of propaganda and fear. These cells need to be started prosecuted under some serious criminal charges. Here's perfect chance for judges to get involved and save the day.
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Re: Wuhan Coronavirus Resource Thread

Post by a_bharat »

https://www.livemint.com/news/india/nat ... 60308.html
Hyderabad-based Natco Pharma Limited on Monday said it has applied to the Central Drugs Standard Control Organisation (CDSCO) for approval of Phase-III clinical trial of Molnupiravir Capsules, to be used for the treatment of Covid-19 positive patients.

The capsule has been developed by American pharma major Merck along with Ridgeback Biotherapeutics.

According to a press release from Natco, pre-clinical data have shown that Molnupiravir has broad anti-influenza activity, including highly potent inhibition of SARS-CoV-2 replication.

"Patients treated with Molnupiravir achieved response within 5 days of therapy indicating that the duration of treatment with Molnupiravir is short, with the additional advantage of being an oral therapy," it said.

Natco is hoping that CDSCO would give emergency approval of this drug based on "compassionate use" for patients.

"Compassionate use" approval is given for investigational drugs so that a patient with an immediately life-threatening condition can gain access to the drug.
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Re: Wuhan Coronavirus Resource Thread

Post by srai »

Great breakthrough on Tejas OBOGS! Exactly like how I was imagining it to be deployed :idea:

Lucknow: DRDO hospitals to harness Tejas tech for oxygen fix

LUCKNOW: At at time when the gap between the demand and supply of oxgen is continuously widening, the makeshift hospitals to be set up by the Defence Research and Development Organisation (DRDO) in Lucknow are likely to have their own oxygen supply with the help of a technology used in light combat aircraft Tejas fighter jets.
This is the first time that the self-sustainable oxygen generation technology for fighter pilots will be used in makeshift hospitals in Uttar Pradesh.


Defence minister and Lucknow MP Rajnath Singh sent a team of DRDO officials to the state capital on Friday to start the process for setting up of hospitals at Haj House and Golden Blossoms resort. The hospitals, likely to get ready by next week, will have around 250-300 beds each and will be run by the doctors, nurses and support staff of Armed Forces Medical Services.

According to defence ministry sources, DRDO has developed a medical oxygen plant as a spin off technology of the ‘On board oxygen generation system’ (OBOGS) of LCA Tejas.

On condition of anonymity, an official told TOI: “This plant can provide medical grade oxygen round-the-clock at a high-flow rate catering to at least 50 ventilator ICU beds. This technology will be used to activate oxygen plants at Covid hospitals.”

The technology, which has been developed by DRDO’s Defence Electromedical & Bio-Engineering Laboratory (DEBEL), breaks down molecular components of the atmospheric air to provide continuous oxygen to pilot within the aircraft for long duration and high altitude flights.

Once set up, the technology will help in continuous supply of oxygen to critical beds for Covid patients, refilling of oxygen cylinders and eradicating logistical problems related to cylinder transportation from one point to another, apart from sharing the burden of oxygen demand and supply.
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Re: Wuhan Coronavirus Resource Thread

Post by srai »

Better details

DRDO offers spinoff tech from Tejas onboard oxygen system to hospitals fighting COVID-19
Anantha Krishnan M
Published: April 24, 2020 04:08 PM IST

Bengaluru: A spin-off from a critical technology that would aid future pilots of Indian Air Force (IAF) flying the Light Combat Aircraft (LCA) Tejas with non-stop supply of oxygen while undertaking long-endurance missions is now being offered to hospitals combating coronavirus.

This product to fly out from the hangars of Defence Research and Development Organisation (DRDO) is in the form of a Medical Oxygen Plant (MOP), is an offshoot technology from the onboard oxygen generation system (OBOGS) being developed for Tejas.

The MOP technology is developed by Defence Bioengineering and Electromedical Laboratory (DEBEL), a life sciences wing of DRDO situated in Bengaluru’s C V Raman Nagar.

MOP utilizes pressure swing adsorption (PSA) technique and molecular sieve technology to generate oxygen directly from atmospheric air.

The OBOX technology for Tejas being developed by DEBEL has been approved by the Centre for Military Airworthiness and Certification (CEMILAC), an agency mandated to certify the products.

Sources in DRDO confirm to Onmanorama that the oxygen generator components have been developed by DEBEL and the technology has been transferred to a Coimbatore-based firm.

“This plant will be useful to provide oxygen supply during corona pandemic in hospitals in urban and rural areas. The installation of MOP helps in avoiding hospital’s dependency of scarce oxygen cylinders,” says a DRDO official monitoring the work.

Ever since the coronavirus outbreak, the scientists at DEBEL have been working developing various products for the healthcare sector.

Masks and sanitizers developed by the lab have already been distributed in bulk, while work on affordable ventilators has reached advanced stages of completion.

Several Benefits

Scientists say that the MOP can be used extensively at hospitals situated at high altitude and inaccessible remote areas.

“There are several benefits including reduced logistics of transporting cylinders to these areas, low cost, continuous and reliable oxygen supply available round the clock. The facility can also be used for filling the cylinders in addition to direct installations at the hospitals,” says a scientist.

DRDO has already used this technology to install oxygen plants at some of the military hospitals and establishments in North-East and Leh-Ladakh regions.

The first such plant set up in Tawang is operational since 2017 and it complies with international standards like ISO 1008, European, US and Indian pharmacopoeia.


Unique Features

The MOP has high reliability, full independency with automation and reduces logistics. This safe technology needs only minimum maintenance and can be operated at low cost. It is free of oil and produces oxygen instantaneously from ambient air and works round-the-clock.

The electric oxygen compressor can charge the cylinders up to 200 bar. It has stored oxygen supply for transient power failures and boasts of low energy consumption. It can also be operated via remote control.

The MOP contains an air compressor, air dryer, oxygen generator and a compressor. Each plant can fill up to 47 Litres (water capacity) cylinders at a rate of 60 per day and operate round-the-clock.

“The oxygen capacity depends on the pressure of filling, which is about 150-200 bar. The industry holding the transfer of technology can ramp up its production and can install up to 20 plants in five weeks,” says a scientist.

The system can cater to 60 patients at a flow rate of 5 LPM (litres per minute) and can charge up to 60 cylinders per day. The capacity can be varied as per the hospital requirement. The plant is designed for a capacity of 18 NM3 per hour. (NM3 or normal meter cubed per hour is the unit to measure the gas flow rate.)

The oxygen capacity depends on the pressure of filling, which is about 150-200 bar.

The scientists at DEBEL also designed three types of aluminium cylinders which can be used for oxygen filling. The oxygen-carrying capacity of these cylinders varies and is designed to operate under different pressure parameters.


For the Tejas OBOGS, the scientists have used a zeolite-based technology and the system will undergo trials soon.

“We have completed all ground-based trials of OBOGS on the test rigs and the pilots are satisfied with the results. It will now be integrated on one of the test variants of Tejas for flight trials. It has been already cleared by the Regional Centre for Military Airworthiness,” says an official.

The Ministry of Civil Aviation and Indian Railways are among the several prospective users who have shown interest in DEBEL’s MOP.
Last edited by srai on 26 Apr 2021 15:27, edited 1 time in total.
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Re: Wuhan Coronavirus Resource Thread

Post by g.sarkar »

I just watched BBC World News and CNN. Both are having a field day on the Covid news from India. India's hopes are dying and the anger against PM Modi is growing is what they report. CNN also reports the central government has been trying to censure the news in Twitter instead of containing the pandemic. They are showing funeral pyres in different cities and interviewing common people and doctors to show how inefficient the government is. People are dying in front of hospitals, who are refusing to take in more patients due to the lack of oxygen cylinders, which is available to the rich in black market. Of course emergency help is coming from the US, UK, European Community and Singapore to save the day.
I think they will use this to go after Modiji and blame every thing on him.
Gautam
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Re: Wuhan Coronavirus Resource Thread

Post by g.sarkar »

https://www.cnn.com/2021/04/26/india/in ... index.html
As India breaks another global Covid-19 record and hospitals run out of oxygen, countries pledge assistance and aid
By Jessie Yeung, CNN, April 26, 2021

As India fights a devastating second wave of Covid-19 that is killing thousands each day, international efforts to help tackle the crisis are hastening, with both Britain and the United States pledging aid and much-needed medical supplies.
The second wave, which began in March, has escalated rapidly, with India recording more than a million new cases in just three days. For the past two weeks, medical facilities have been running out of oxygen and ICU beds, with patients left outside hospitals waiting for care.
On Monday, India reported 352,991 new cases and 2,812 virus-related deaths, marking the world's highest daily caseload for the fifth straight day.
The situation is particularly dire in the capital New Delhi, which is under lockdown until May 3. The city is facing severe oxygen shortages. Delhi does not produce its own oxygen and relies on resources supplied by the central government, according to Delhi's Chief Minister Arvind Kejriwal.
Several Delhi hospitals tweeted SOS messages over the weekend appealing for oxygen supplies. On Saturday, at least 20 critically ill patients died after oxygen supply was delayed at one Delhi hospital.
In a tweet Sunday, Prime Minister Narendra Modi said his administration will set up 551 oxygen generation plants "in every district to ensure adequate oxygen availability."
The central government has come under fierce criticism within the country for its handling of the outbreak, which has seen overwhelmed hospitals and residents post pleas on social media for more supplies from state and federal officials. Many have turned to the black market in a desperate attempt to save their loved ones.
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https://www.bbc.com/news/world-asia-56883483
India Covid: Anger as Twitter ordered to remove critical virus posts
Thousands across India are outraged after the government ordered social media platform Twitter to remove posts critical of its handling of the virus.
A Twitter spokesperson confirmed it had blocked some material from being viewed in India.
The country faces a massive surge in cases, with many of its hospitals facing an oxygen shortage.
One Twitter user accused the government of "finding it easier to take down tweets than ensure oxygen supplies".
India recorded 352,991 new infections on Monday and 2,812 deaths - the highest single-day spike so far.
'A humanitarian disaster'
The government made an emergency order to censor the tweets, Twitter revealed on Lumen, a database that keeps track of global government orders around online content.
Twitter did not specify which content it had taken down but media reports say it includes a tweet from a politician in West Bengal holding Prime Minister Narendra Modi directly responsible for Covid deaths, and from an actor criticising Mr Modi for holding political rallies while the virus raged.
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Gautam
Cyrano
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Re: Wuhan Coronavirus Resource Thread

Post by Cyrano »

The humanitarian disaster these foreign media are salivating to see hasn't happened yet, in the India's scale of numbers. They will cry even shriller in the coming weeks as they see the disaster they're hoping for will be averted.
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Re: Wuhan Coronavirus Resource Thread

Post by Raja »

Anecdotally, I don't believe the official numbers that have been reported from Ahmedabad. I am not sure how true this article is, but crappy data will only hurt us in the long run.

https://www.thehindu.com/news/national/ ... 412371.ece

Figures from main government hospitals in Ahmedabad, Surat and a few districts reveal deaths many times higher than being reported by the health authorities.
Discrepancy between the government figures of COVID-19 deaths and figures from hospitals and crematoria/burial grounds in the State appears growing in Gujarat as the State is grappling with the pandemic’s second wave.
Dilbu
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Re: Wuhan Coronavirus Resource Thread

Post by Dilbu »

As soon as the vaccine production scales up we should open 24 hour vaccination camps all over the country with the help of IA. IA is vaccinated and ready.
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Re: Wuhan Coronavirus Resource Thread

Post by darshan »

Raja wrote:Anecdotally, I don't believe the official numbers that have been reported from Ahmedabad. I am not sure how true this article is, but crappy data will only hurt us in the long run.
Many that I have talked to decided to kick the can and not go to a hospital. I'm not sure if they count this bunch too. In last few days, called three such people to have a last conversation. They were all content with their lives and didn't want to have their kids use their savings.

Cremations are counted and excess deaths are reconciled I believe in the end. I'm not even sure if diverting resources towards getting the numbers correct is worth it. One uses trends to run algorithms to adjust. There's more than enough data to indicate trends. However, it does matter from the perspective of elections. Like how Mexican authorities were made to correct their death numbers and news were run everywhere.
darshan
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Re: Wuhan Coronavirus Resource Thread

Post by darshan »

SMC Appeals Youth to Donate Blood before Getting Vaccinated
https://www.deshgujarat.com/2021/04/26/ ... accinated/
...
Considering the shortage of blood in the current pandemic situation, SMC has appealed to the public that those above 18 years of age should donate blood before getting vaccinated from 1st May 2021 onwards. Patients undergoing the treatment of Covid-19 and other diseases in the city; and especially pregnant women often require blood. SMC has appealed to youth to donate blood before taking the vaccine as it can be a life-saver for other people.
nam
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Re: Wuhan Coronavirus Resource Thread

Post by nam »

Mumbai seems to have controlled it's oxygen and hospital requirements.

Delhi, as usual continues to the shining becon of disaster. It might be couple of weeks, before things become stable.

Time to focus on other parts of the country. KR goes for 2 week lockdown, other than for people working in industries.

The only saving grace is that the death rate is under 1%, despite the large infection rate. The infection numbers don't matter. The increase seen could be given the large testing numbers.

What matters is positivity and death rates.
darshan
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Re: Wuhan Coronavirus Resource Thread

Post by darshan »

Centre guides States with a new Phase-3 vaccination strategy
https://www.deshgujarat.com/2021/04/24/ ... -strategy/
...
Dr R S Sharma noted that the CoWIN platform has now stabilized and is working at scale flawlessly. It is equipped to handle the complexities of the new phase of vaccination starting from 1st May. He highlighted the importance of uploading correct and timely data by States/UTs as any incorrect data would compromise the integrity of the entire system.
With regards to the Phase III Vaccination strategy from 1st May 2021, the States were specifically advised to:

Register additional private COVID Vaccination Centres (CVCs) in mission mode by engaging with private hospitals, hospitals of industrial establishments, Industry Associations, etc., coordinating with designated appropriate authority, mechanism for applications/requests and their processing and monitoring of pendency of registration.
Monitor number of hospitals that have procured vaccines and have declared stocks and prices on COWIN.
Schedule Vaccination for eligible population for providing adequate visibility of vaccination slots on COWIN.
Prioritize Decision regarding direct procurement of vaccines by State/UT Government.
Publicize about facility of ‘only online registration’ for age groups 18-45 year.
Train CVC staff about Vaccination, AEFI reporting and management, Use of COWIN – Training schedule and Reconciliation of vaccine stocks have been already provided to private CVCs.
Coordinate with law-and-order authorities for effective crowd management at CVCs.
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aakashrj
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Re: Wuhan Coronavirus Resource Thread

Post by aakashrj »

Raja wrote:Anecdotally, I don't believe the official numbers that have been reported from Ahmedabad. I am not sure how true this article is, but crappy data will only hurt us in the long run.
The actual number of deaths in Gujarat are definitely under reported. There is a local daily in Jamnagar, Gujarat which publishes every death in COVID ward. Now entire hospital is COVID hospital. Although, this civil hospital is bigger hospital, and handling many patients from other districts. The official death count of Jamnagar district has never crossed 10 in last few days. However, list published in local daily everyday has around 100 deceased names.

https://www.nobat.com/news4370-nd-de3ee ... 03630.html

I personally know 1-2 people mentioned in the deceased list. So, it cant be complete hoax. There is probably ICMR guidelines which doesn't qualify every death as covid.

I personally don't care about the number. I have visited hospital last week everyday as one of my family member was admitted due to COVID. The situation is really dire, but everybody is getting beds. The oxygen beds takes around 4-5 hours to get allocated since last 2 days.
chetak
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Re: Wuhan Coronavirus Resource Thread

Post by chetak »

nam wrote:Mumbai seems to have controlled it's oxygen and hospital requirements.

Delhi, as usual continues to the shining becon of disaster. It might be couple of weeks, before things become stable.

Time to focus on other parts of the country. KR goes for 2 week lockdown, other than for people working in industries.

The only saving grace is that the death rate is under 1%, despite the large infection rate. The infection numbers don't matter. The increase seen could be given the large testing numbers.

What matters is positivity and death rates.
there is huge black marketing of oxygen and all covid medications.

Hospital beds, especially in the private and and other hospitals in outlying areas

the people involved are mainly municipal employees posted as nodal officers to oversee the distribution of oxygen.

the municipal employees are fleecing people in crematoriums.

300rs worth of oxygen is being sold at 2000rs in bangalore and there are plenty of takers. Our guys are very adept at vulture marketing and feeding off the miseries of their fellow human beings

There is no shortage of oxygen but it is an artificially created distribution bottle neck that is being exploited to the hilt.

patients are being told to go home after 5-6 days and free up the scarce beds for more serious patients. Treatment continues at home in a more controllable environment

earlier, even patients who got well would flatly refuse to vacate the hospital beds fearing a relapse which rarely ever occurred.

this is true in almost all hospitals but now the discharge policy has been tightened so that beds are not hogged by those who have improved enough to continue their treatments at home
nam
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Re: Wuhan Coronavirus Resource Thread

Post by nam »

There has been 40K deaths since 1st of March. Let's assume 3 time more, to cater to "under reporting". 120K deaths.

In the same period we have done 130 million vaccinations. All those 120K had to do was to take 1 dose out of 130M doses. They could have been alive today, without having to run around for hospital beds.

I feel furious to see people of twitter pleading for bed and oxygen in Delhi, mostly for people above 45. When they could have put 1/10th the effort in getting a vaccine.
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Re: Wuhan Coronavirus Resource Thread

Post by jamwal »

How are healthy young people (less than 40 years) who had no known direct exposure to anyone infected, wearing masks, using sanitizer very liberally and staying home catching corona? Surprisingly large number of such cases in my Delhi circles.
BTW, any source for securing oxygen in New Delhi?
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Re: Wuhan Coronavirus Resource Thread

Post by durairaaj »

jamwal wrote:How are healthy young people (less than 40 years) who had no known direct exposure to anyone infected, wearing masks, using sanitizer very liberally and staying home catching corona? Surprisingly large number of such cases in my Delhi circles.
BTW, any source for securing oxygen in New Delhi?
Covering eyes is very important. This is not generally informed to the public. But medical professionals do wear them.

Wear zero power eyeglasses or face shield along with mask to protect.
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