Wuhan Coronavirus Resource Thread

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syam
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Re: Wuhan Coronavirus Resource Thread

Postby syam » 07 Apr 2020 00:46

Arun.prabhu wrote:The Chinese researchers now state that the massive pollution in Wuhan may have contributed to the die off. Not to mention whatever they used to disinfect the city. Remember, they SO2 concentration was at one time 1800ppm and that was noted here.

https://www.eurasiareview.com/01022020- ... onia-oped/


did you just quote feb article?

I know you are panic posting and being in denail mode. take a breather and go through the evidence available on the this thread itself. sulfur emission happens mostly through coal burning. ccp for all its faults, doesn't take second chances. they burned their dead using coal!!! no matter what you use, the virus will keep living unless you burn the whole thing down. another point we have to consider as some folks want to bury their dead here.

no country returned to 'normal' yet. Singapore and Japan are under lockdown now after flattening the curve. Europe yet to reduce their numbers. china, no one knows what's happening there. why do you want to risk our country, sirji?

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 00:48

Folks no more on the above lines, people indulging in further discussion along the above lines will get a warning. Kindly cease and desist

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Re: Wuhan Coronavirus Resource Thread

Postby Arun.prabhu » 07 Apr 2020 00:51

I did not peddle conspiracies. The arguments I made were backed up by data collated by the folks at swprs from published journals and studies. Difference that seems to sail right past the heads of most BR members.

And anyways, at this point, I've had it. <abusive language edited>

nachiket wrote:Arun Prabhu please peddle your conspiracies elsewhere. This is not the thread (or forum) for it. Failure to comply will result in an immediate ban.
Last edited by nachiket on 07 Apr 2020 01:00, edited 2 times in total.
Reason: user banned

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Re: Wuhan Coronavirus Resource Thread

Postby milindc » 07 Apr 2020 00:55

sudarshan wrote:Suryag ji, you don't have to put words in other people's mouths. The other side of the argument is not that those doctors would have died in traffic accidents, the other side (at least from me) is that most of those doctors were in their 60's, 70's, 80's, and one even in 90's. That Swiss site links to the data site that Arun.Prabhu also posted. Many of those doctors are also listed as "pensionato" (retired), "Ex-medico," etc. Probably retired folk hauled to the front-lines of fighting the disease, with predictable results.

At least on my side, I'm not arguing against the current lockdown. In the face of an unknown disease, it was the right thing to do, and Modi did a commendable job of instituting an early lock down.

Now the need is to use the chance to make an honest evaluation of the disease and its characteristics. This need is not served by: labeling every death with Coronavirus as a "CV death":

In other words, a 90-year-old man who dies with a fracture of the femoral neck and becomes infected with corona in the hours prior to his death is also counted as corona death. To name but one example.“


A German medical specialist informs us: „From my medical point of view, there is some evidence that some of these people may have died as a result of the measures taken. People with dementia get into high stress when major changes are made to their everyday lives: isolation, no physical contact, possibly hooded staff.“ Nevertheless, the deceased are counted as „corona deaths“ in German and international statistics. In connection with the „corona crisis“, it is now also possible to die of an illness without even having its symptoms.


Why inflate the death count with "data" like the above? Any particular reason, maybe to justify the current lockdowns, or maybe to plug a vaccine?

The need is also not served by: publishing data on the "exponential rise of CV cases" without publishing corresponding data on the "exponential rise of testing for CV cases" (in fact, the fraction of positives is practically flat). To its credit, worldometer is now showing data on the number of tests as well. The flat fraction of positives to me indicates that - in the pockets where "new cases" are occurring, what we're seeing is actually the fact that up to 20% of the population has already been infected. The testing is turning out to be a poll of this infection - increased testing, corresponding increase in cases. In India, that fraction seems to be 2.5% in the general population, about 10% in the Mosque revelers.

So what I'm saying is, no issues with the current lockdown, no need to justify it, it was the right thing to do. The issue now is - are we honestly evaluating the need for future lockdowns? Not if we keep spreading unnecessarily inflated numbers of deaths and also showing "exponential spread" without the context of "vastly increased testing."

Like I said, I'm very interested in seeing how well that prediction of "93,000 deaths in the USA" pans out (this prediction, once again, ALREADY ACCOUNTS FOR THE EFFECTS OF THE LOCKDOWN, according to the author(s) of the paper). If this turns out true (I hope not), then the experts have a good handle on evaluating the seriousness of this disease. If this prediction turns out to be greatly exaggerated, then - I'll have a hard time buying the logic for future lockdowns. Another couple of days or so should tell us.


Question is more simple. Are you willing to be in shoes for Nurses and Doctors treating infected Covid patients. Are you willing to put your life in danger (Yes, it might be 0.5% if you get infected but still) ?
If not, then please desist from saying.. yes, look at the economic, only the old folks are dying who anyway will pass away.
Yes, everyone will pass away one day, but the question is whether one is willing to take that chance himself?
If that 70 year old Doctor, didn't get infected by Covid would he have survived for another 5 years?

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Re: Wuhan Coronavirus Resource Thread

Postby nachiket » 07 Apr 2020 00:56

Alright you get your wish Arun Prabhu. Banned!

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 07 Apr 2020 01:01

disha wrote:
KJo wrote:I have been tracking Confirmed cases.

US: The daily growth is reducing. It is now at 8%. Was in teens earlier, and the decline is also steady. By around Apr 18, we should see 0% growth. Then decline.
India: The growth is very erratic, so hard to see any trends emerging. I think it will be a few more days for that. India has to be watchful as there are crazies who want to ruin things for everyone.


In India look at cluster-specific growth. For example, look at hot spots like Mah, Delhi, Kerala & Rajasthan.

Even better, look at clusters district wise from http://covidindiaupdates.in/

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 01:06

We top of at +500 today, 4290->4778, have 8 more days to go, hope and pray we slow it down considerably.

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 07 Apr 2020 01:06

470 odd cases for today, compared to 600+ yesterday. As expected the lockdown effect is kicking in now. Not out of the woods yet, however a ray of hope.

Frankly we hit the lockdown almost at the right time. We are on our way to 1k+ per day cases.

GoI has allowed limited anti-malaria and paracetamol export.

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Re: Wuhan Coronavirus Resource Thread

Postby syam » 07 Apr 2020 01:17

ANI
@ANI
·
3m
UK Prime Minister Boris Johnson, who had tested positive for #Coronavirus late last month, has been taken to intensive care: UK media

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Re: Wuhan Coronavirus Resource Thread

Postby saip » 07 Apr 2020 01:25

Boris Johnson in intensive care. Mere flu would have put them there or just the common pneumonia would have put him there so fast? Nothing to do with COVID19? It is like any other virus?

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 01:36

The number of daily deaths in Italy, Spain, Ger is on an encouraging down trend, as with my wishes for anyone who gets infected, may Boris Johnson recover quickly

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 07 Apr 2020 01:48

Horrible disease and can't believe we had a person foolish enough to claim it was over hyped. Anyone who thinks this is perfectly welcome to step outside and volunteer to assist doctors, nursing staff etc. To sit at home in front of a computer and take the words of academics who are merely looking at 2nd order effects and claiming it is just like flu is beyond bizarre when so many details now exist from frontline responders on how it makes people who are vulnerable desperately sick as well as those who thought they were immune. Stupid to downplay this.

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 07 Apr 2020 02:01

https://www.mohfw.gov.in/pdf/3Containme ... 9Final.pdf

The govts very detailed containment plan. This is the one coupta was talking about. It seems our administration is also rising to the challenge.

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Re: Wuhan Coronavirus Resource Thread

Postby Rsatchi » 07 Apr 2020 02:09

Boris Johnson admitted to ITU
Scary stuff
Dominic Rabb stand in leader

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Re: Wuhan Coronavirus Resource Thread

Postby Rsatchi » 07 Apr 2020 02:11

I was in London 11th to 13th because of wife’s convocation at the college
I am really scared
Hell what is this shit

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Re: Wuhan Coronavirus Resource Thread

Postby Cain Marko » 07 Apr 2020 02:20

Karan M wrote:Horrible disease and can't believe we had a person foolish enough to claim it was over hyped. Anyone who thinks this is perfectly welcome to step outside and volunteer to assist doctors, nursing staff etc. To sit at home in front of a computer and take the words of academics who are merely looking at 2nd order effects and claiming it is just like flu is beyond bizarre when so many details now exist from frontline responders on how it makes people who are vulnerable desperately sick as well as those who thought they were immune. Stupid to downplay this.

Earlier I had few bouts with said worthy who used a lot of data to create a lot of fud to promote the premise that herd immunity is the way forward because the "inevitable" economic apocalypse would be a lot worse.

What I noticed was that the data and arguments were often non contextual and hence fud.

In itself the data might've been ok, for example the analysis of Italian deaths which were overwhelming of older people, who of course have comorbidities. In itself that's fine. But taken in the context of how many of the elderly are therefore susceptible to this disease, the numbers would be staggering. Combine that with the fact that a lot of the younger population today suffers from such conditions too (just check how prevalent diabetes, heart disease and hypertension is in these populations), and you realize that it will take a heavy toll on this population too.

The entire idea of herd immunity seems to be a Thanosian venture to cull the "weak". I can see the temptation as a movie theme but in reality, it is genocidal insanity. Interestingly and perhaps not too strangely, only 2-3 countries seem to have played with this idea. And all of them have a strong Protestant bias. Not too dissimilar from your run of the mill Tablighi.

Kudos to mods for fixing the issue
Last edited by Cain Marko on 07 Apr 2020 02:28, edited 1 time in total.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 07 Apr 2020 02:27

It clearly indicates said worthy has no medical awareness worth his name.

As you noted, literally every other person in India is genetically predisposed to some ailment or the other which is kept in control with medicines or plain luck.

If any aggressive disease like this virus, takes off the controls with one set of organs, i.e. the lungs, then what does it do to the rest?
People with COPD, CKD, Hypertension are all at risk. Young folks with none of the above diagnosed are coming out barely alive with reduced lung function.

This herd immunity stuff sounds like the kind of crazy, we have no answers plan which has landed the UK PM in the ICU. I am glad our "chai-wallah" PM had the foresight and straight forward sense to get the experts at ICMR and elsewhere to come up with a much better plan rather than this sort of insanity.

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Re: Wuhan Coronavirus Resource Thread

Postby Suraj » 07 Apr 2020 02:44

Arun.prabhu wrote:I saw that chart and I'm happy that our government is trying to take care of us, but the disease isn't as deadly as we believe it to be... Do we close our roads to save the 150000 annual dead? Or ban all industries to reduce the incidence of heavy metal poisoning and the shortening of life expectancy that causes? Have we banned sugar to fight the diabetes epidemic that will claim so many millions decades before they would otherwise have died?

None of your arguments make any sense, I'm afraid.

First you conflated the lockdown with an attempt to lower case incidence. However, the lockdown is to flatten the curve. There's an element of potential reducibility from lack of contact, but that goes away as the lockdown is removed, and therefore the public policy goal is to have a lockdown long enough for a substantial number of carriers to recover, and make the progression a slow burn endemic illness on par with the transmission rate of conventional flu.

Secondly, you conflate the argument with that of diabetes and auto accidents. Neither of these have transmittability, i.e my consumption of refined sugars will not give those sitting around me diabetes, and similarly your wrapping your car around a lamppost won't spontaneously make others drive off a cliff too.

A lockdown is a public policy measure taken to tamp down the transmission speed of a novel virus with the ability to simultaneously put a large number of people in hospital because the virus is novel, i.e. we have no herd immunity yet. The entire purpose of the lockdown is to generate herd immunity the normal way - by causing transmission at a low rate even as the new case count and new recovered counts are roughly on par, as opposed to case count being orders of magnitude larger than the recovered count, as is the case now.

I don't get the 'don't do lockdown, let herd immunity work' argument. The lockdown approach IS the herd immunity approach. No lockdown at all is an out of control fire burdening first responder and hospital facilities nationwide and causing a breakdown in social cohesion and trust in public institutions.

Had this NOT been a novel virus with the population having some greater degree of natural built in immunity, none of these would have been required, because the transmittability would be lower and thus pressure on public services would correspondingly be lower. The concept of a sweeping novel virus has been wargamed by many authorities, and it's always been known that a situation like the present was a case of when and not if. Everyone with a functioning public government has imposed some degree of lockdown or the other, with those who delayed (including UK leadership) having large numbers in hospital in the process.

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Re: Wuhan Coronavirus Resource Thread

Postby VinodTK » 07 Apr 2020 03:04

From TFIPOST: ‘We will give you masks if you accept Huawei 5G,’ China is forcing Coronavirus-hit countries to kneel before Huawei
As if manufacturing the Coronavirus Pandemic that has enfeebled countries across the world was not enough, Beijing is now also looking to profiteer out of the global public health crisis- pushing its 5G tech giant, Huawei into the West, even extorting other countries into allowing it.

The might Dragon knows that countries across the world have currently slipped into distress, and has thus launched a propaganda war against the Coronavirus-battered countries in a mischievous attempt to pose itself as the country that will bail the world out of the Coronavirus Pandemic.

Chinese State media has now started resorting to publishing photographs of the country’s medical aid (read “mask diplomacy”). Even the Chinese conglomerates have come out donating medical gear to other countries, and one of those corporate giants which has been a major component of Beijing’s medical aid-PR campaign is the 5G service provider Huawei, a telecom major that was till yesterday being rejected by countries across the world.
First indications of China looking to profiteer out of the Pandemic in terms of pushing Huawei came when CCP mouthpiece Global Times issued an open threat, quoting a Chinese analyst as saying, “US moves to restrict sales of technology to Huawei may backfire amid the #COVID19, as China could ban the export of face masks and other medical gear to America.”

The threats are becoming that much clearer with Huawei’s Chairman-CEO Eric Xu warning that the US moves to step up pressure on the Chinese tech giant could spiral into retaliatory action from Beijing that could damage its worldwide industry.

China knows that with critical supply chains snapped, and countries desperate for medical supplies, any medical gear coming from China is bound to be treated as a favour even if it is an outright sale and not donations/ aid. After all, China is the only country in the world that has come back to function at some level.

And Beijing is targeting one country at a time, taking full advantage of the fault-lines emerging between the rest of the world amidst desperate national attempts to ward off the Wuhan virus. For example, in the case of Canada, Trudeau hit out at the Trump administration following the latter’s decision asking a manufacturer to stop exporting N95 masks to Canada and Latin America.

This is where Beijing has stepped in exporting millions of masks to the country, and this alters the political calculus between Beijing and Ottawa. Only a little more than a year ago, Huawei senior executive Meng Wanzhou had been arrested in Vancouver, Canada on an extradition request from the United States. This had kicked off bilateral tensions between Canada and China, but now China’s “mask diplomacy” will make inroads for Huawei in Canada.

In the case of France, the Chinese President Xi Jinping is reportedly not even beating around the bush, and when the French President Emmanuel Macron requested supply of masks, Jinping bluntly made it clear that medical equipment would be supplied only if France accepts Huawei’s 5G technology.

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Re: Wuhan Coronavirus Resource Thread

Postby Suresh S » 07 Apr 2020 03:07

This virus is an existential threat to India(I almost want to say, was but touch wood ) and I congratulate the prime minister for having the foresight to react the way he did.A country with, at the moment poor hygienic practices, poor health infra for the massive population of this size and densely populated if unchecked this virus had the potential to have caused casualties in the millions. Prime minister,s govt has done a fantastic job under the circumstances. My only criticism is the way he is rx the peacefuls and traitorous press with kid gloves.

Unrelated but the first news today that brought tears to my eyes and the only news I watched today was not corona virus but our brave hearts paras fighting the scum on the LOC. Jai Hind.

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 07 Apr 2020 03:11

If our companies want to play big in the future, they need to show up now. The CCP is now fundamentally holding the world at ransom, using a mess they created in the first place.

It is time our companies buckle up and churn out masks, medical kit, medicines and support at war scale. World is looking at an alternate to the CCP fiefdom and we will not get another opportunity.

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 03:24

REminds me of an incident when I had spent sometime in the companies being mentioned above, we first saw a card that was exactly an E/// card with the same lady name on it, second incident I lost a laptop when I had gone for a test campaign there. Sad to see France being squeezed, these morons screwed up ALU and NSN anyways it is still not late, go whack some heads in Finland and get NSN to deliver to Europe

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 07 Apr 2020 03:48

in England, 26% of the ICU patients are current smokers. It could be one of the prime reason for younger people getting really sick.

There are enough people of all age group with this "underling condition", to cause havoc.

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Re: Wuhan Coronavirus Resource Thread

Postby Primus » 07 Apr 2020 06:28

milindc wrote:
Arun.prabhu wrote:Read my response to handmadu.

viewtopic.php?f=1&t=7800&start=4760#p2425882

The numbers of the ground. Not the Chinese made up numbers, but what we're seeing in the west. The official counts are skewed towards symptomatic cases and serious ones at that, thanks to selection bias. It will remain that way until people start doing random tests for the whole population.



I don't know if you really know the situation on the ground. The medical system is completely overwhelmed by the cases. Every hospital in UK has postponed non critical procedures and allocated those ICU units along with hospital beds for treating the infected. And all those ICU units are close to being full. They expect more cases coming in.

In US, similar situation where the staff is completely over worked and system has become over burdened.
Now you might say, let them die, but the current world order doesn't work that way.


With respect to our friend, one only has to see the situation in the hospitals in hotspots first hand to realize how this is different from anything else we've encountered before. I've had the flu several times myself, including the H1N1, with fever of 105F, so many of my patients and family members/friends have had it, nobody died from it. yes, people do die from the flu but typically these are the as expected, older and more infirm persons.

COVID is killing people of all ages, even young and healthy ones which rarely if ever happened in my experience with the flu. The closest we've seen is AIDS but it killed ever so slowly. I lived through the HIV epidemic working in a hospital with perhaps the largest population of AIDS pts in the world, entire wards dedicated to it. And yet, this virus scares me. One of my partners is sick at home with it, on oxygen. Only the really sick patients are in the hospital, everyone else is being sent home to recover. My PA is recovering at home too. Our local hospitals are overflowing, ERs are backed up with 40-50 patients waiting for beds, they have opened up wards which were closed for lack of use or renovations, there is a severe shortage of nurses, respiratory therapists and intensivists, people are being paid twice the normal for overtime work, I keep getting emails daily requesting more people to volunteer.

It is a healthcare crisis which is unprecedented, at least in the US and especially New York. All elective procedures are canceled, none of us are doing anything, since the hospital facilities are all tied up with COVID.

I don't care if the entire population is not being tested, or if the number of COVID positives that end up in the hospital is a minuscule fraction - the point is, there are enough sick, no, very sick people who are flooding the hospitals and people are dying within days of being admitted. Rarely have I seen a disease that kills so quickly and so randomly. The manner of death as our esteemed Dr. Ratnadip has pointed out, is also frightening and it does not kill instantly as a car crash would.

All those arguments about traffic accidents are pointless - death is death. I can't imagine how people - all with good intentions - cannot see this pandemic for what it is, a killer of humanity that is truly invisible and unpredictable. All the data means nothing to me, when you see it with your own eyes, you realize what the truth is.

Sorry for the rant but stuff like this really gets to me, when I see my brothers in arms putting their lives at risk and dying, while the narrative being spun is that it is all data manipulation.

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Re: Wuhan Coronavirus Resource Thread

Postby Primus » 07 Apr 2020 06:38

DrRatnadip wrote:
Primus wrote:Not sure if this makes sense but there is a video from an ER doc at Maimonides in Brooklyn claiming we've all got it wrong and that the virus does not cause ARDS but a form of hypoxia similar to HAPE and that PPV is in fact more harmful.

There is a paper out from China suggesting viral proteins binding with heme and porphyrin disabling its O2 carrying capacity and how Chloriquine and favipiravir may be helpful in this situation.


COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism

Any intensivists here with thoughts on this? Dr. Ratnadip?



Both video and article make some bold claims.. Both authers doesnt seem to come from medical background.. Study of viral protein binding to heme is just computer simulation and needs experimental evidence.. One more thing that comes to mind is if virus is affecting at such basic step of oxygen exchange why so many patients are spared of this effect??

In youtube video gentleman is recommending change in currently used ventilator settings.. He is suggesting using low PEEP in stead of high PEEP.. Both settings have there own disadvantages.. High PEEP uses higher pressure to pump air in alveoli that are collapsed due to fluid.. More pressure can sometimes damage delicate alveoli causing Ventilator induced lung injury.. Lower pressure will have less chance of injury but optimal air delivery in each alveoli may not be achieved.. Current guidelines favour using High PEEP ( positive end expiratory pressure)..


Doc, thanks for your insights. It has been many, many years since I worked in an ICU, but I am familiar with PEEP and its use/misuse. Even in my time it was really difficult to decide how much PEEP to put on if at all. A lot of it was hit and miss, wait and watch.

However, there is still so much uncertainty about optimal management of COVID lung injury or the disease itself. Here in our area, they have finally started using Hydroxychloroquine. Not sure if it is helping or not since I am not directly involved any more.

What we do know is that it will be a few more weeks before enough data accumulates. Until then people like our friend from Maimonides will keep popping up with radical theories.

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Re: Wuhan Coronavirus Resource Thread

Postby g.sarkar » 07 Apr 2020 08:20

https://www.theguardian.com/world/2020/ ... -equipment
US blocks millions of N95 face masks headed for Canada
US officials stop shipment at 3M factory after Trump invoked Defense Production Act to stop exports to Canada and beyond
Leyland Cecco in Toronto and Julian Borger in Washington, Mon 6 Apr 2020

US officials have stopped nearly three million specialized masks from being exported to Canada’s most populous province, amid mounting fears that Ontario will run out of supplies for medical staff battling coronavirus by the end of the week.
Donald Trump on Friday invoked the 1950 Defense Production Act giving the government “any or all authority” to stop 3M exporting N95 respirators to Canada and Latin America. The masks, which filter out 95% of airborne particles, are seen as a critical tool for frontline healthcare workers in the fight against Covid-19. But as supply shrinks, countries and local governments are locked in a desperate battle to access whatever equipment is available.
At a press conference on Monday, Ontario premier Doug Ford said the 500,000 masks had been cleared for release, but nearly three million masks were intercepted by US officials at 3M’s South Dakota Facility.
“We know that the US isn’t allowing supplies across the US border,” Ford said. “The hard truth is, our supplies in Ontario are getting very low and the more new cases we get, the more demand there is on our resources.” 3M initially resisted the president’s executive order, warning in a statement the move would have “significant humanitarian implications” for countries desperate for safety equipment.
Over the weekend, Trump harshly criticised the company, warning it would have “a big price to pay”. “We need the masks. We don’t want other people getting it,” Trump said in a Saturday briefing to reporters. “That’s why we’re instituting [the] defence production act. You could call it retaliation because that’s what it is: it’s a retaliation. If people don’t give us what we need for our people, we’re going to be very tough.”
.....
_____________________________________________________________________________________________________________________
https://www.hindustantimes.com/world-ne ... 1bVQJ.html
Trump talks of ‘retaliation’ if India turns down anti-malarial drug request
The American leader went on to add to the threat his long-running grievances with India on trade issues, which have history of eluding resolution.
WORLD Updated: Apr 07, 2020 07:13 IST
Yashwant Raj Hindustan Times, Washington

President DonaldTrump on Monday spoke of “retaliation” if India turned down his request to lift the hold on US orders of an antimalarial drug, which he has touted as a “game-changer” in the fight against the coronavirus despite its untested efficacy, resulting from a blanket ban on export of certain medicines.
The American leader went on to add to the threat his long-running grievances with India on trade issues, which have history of eluding resolution, including an ultimately failed rush by the two countries to stitch together a deal in time for Trump’s first state visit to India in February. This was the first time he had publicly brought up trade after the visit.
President Trump made the request for releasing the hold on hydroxychloroquine in a phone call with Prime Minister Narendra Modi Sunday morning (evening in India). “I said we’d appreciate you allowing our supply to come out, If he doesn’t allow it to come out. That would be okay but, of course, there may be retaliation,” the president said at the daily White House briefing on the coronavirus outbreak, adding, rhetorically for stress, “Why wouldn’t that be?” India has not yet decided either way yet. Prime Minister Modi had told the American leader during the call that India “will do all what we can”.
.....
Gautam

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 09:59

Dr Sirs how is Hydroxychloroquine+zinc+azithromycin doing ?Read a number of anecdotal accounts that emerged today that it is clearing it up in a few hours. Additionally, ivermectin, favipiravir, BCG studies also seem underway. Anyways, am pretty sure you are all reading up on all new emerging studies/anecdotal accounts. My daily routine is check google news for hcq+Zn+zpak, favipiravir, ivermectin , BCG in the evening or morning. Just stay safe all of you, kind of is scary, I heard an account of an Indian family where mother and father(passed away) both are in ICU and the kid has fever. Imagine the situation who can help the kid :(

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 07 Apr 2020 10:24

suryag wrote:Dr Sirs how is Hydroxychloroquine+zinc+azithromycin doing ?Read a number of anecdotal accounts that emerged today that it is clearing it up in a few hours. Additionally, ivermectin, favipiravir, BCG studies also seem underway. Anyways, am pretty sure you are all reading up on all new emerging studies/anecdotal accounts. My daily routine is check google news for hcq+Zn+zpak, favipiravir, ivermectin , BCG in the evening or morning. Just stay safe all of you, kind of is scary, I heard an account of an Indian family where mother and father(passed away) both are in ICU and the kid has fever. Imagine the situation who can help the kid :(


To determine Exact efficacy of these drugs large study will be needed.. But in limited patients they seem to work fine.. Currently used protocol in all COVID positive pts in MH is as follows.:
1) asymptomatic but without comorbidities receive HCQ only
2) asymptomatic but with comorbidities receive HCQ and oseltamivir
3)symptomatic but those without comorbidities get Azithromycin in addition to above
4) symptomatic plus with comorbidities Lopinavir/ritonavir is added

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Re: Wuhan Coronavirus Resource Thread

Postby Cain Marko » 07 Apr 2020 10:27

suryag wrote:Dr Sirs how is Hydroxychloroquine+zinc+azithromycin doing ?Read a number of anecdotal accounts that emerged today that it is clearing it up in a few hours. Additionally, ivermectin, favipiravir, BCG studies also seem underway. Anyways, am pretty sure you are all reading up on all new emerging studies/anecdotal accounts. My daily routine is check google news for hcq+Zn+zpak, favipiravir, ivermectin , BCG in the evening or morning. Just stay safe all of you, kind of is scary, I heard an account of an Indian family where mother and father(passed away) both are in ICU and the kid has fever. Imagine the situation who can help the kid :(

Well that's was a RCT that showed promise in China although the sample was somewhat small. N = 60

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Re: Wuhan Coronavirus Resource Thread

Postby suryag » 07 Apr 2020 10:32

Ratnadip Garu, thats great this was the Zn addition link sir

https://abc7.com/coronavirus-drug-covid-19-malaria-hydroxychloroquine/6079864/

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 07 Apr 2020 10:33

DrRatnadip wrote:
suryag wrote:Dr Sirs how is Hydroxychloroquine+zinc+azithromycin doing ?Read a number of anecdotal accounts that emerged today that it is clearing it up in a few hours. Additionally, ivermectin, favipiravir, BCG studies also seem underway. Anyways, am pretty sure you are all reading up on all new emerging studies/anecdotal accounts. My daily routine is check google news for hcq+Zn+zpak, favipiravir, ivermectin , BCG in the evening or morning. Just stay safe all of you, kind of is scary, I heard an account of an Indian family where mother and father(passed away) both are in ICU and the kid has fever. Imagine the situation who can help the kid :(


To determine Exact efficacy of these drugs large study will be needed.. But in limited patients they seem to work fine.. Currently used protocol in all COVID positive pts in MH is as follows.:
1) asymptomatic but without comorbidities receive HCQ only
2) asymptomatic but with comorbidities receive HCQ and oseltamivir
3)symptomatic but those without comorbidities get Azithromycin in addition to above
4) symptomatic plus with comorbidities Lopinavir/ritonavir is added

Hello Doc, is this protocol devised by ICMR or someone else. Also, are treatment results being shared nationwide? For example are you getting info regarding how similar treatment regimes elsewhere in the country are doing?

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Re: Wuhan Coronavirus Resource Thread

Postby vimal » 07 Apr 2020 10:36

g.sarkar wrote:_____________________________________________________________________________________________________________________
https://www.hindustantimes.com/world-ne ... 1bVQJ.html
[b]Trump talks of ‘retaliation’ if India turns down anti-malarial drug request

Gautam


India should just export the malaria drug for 10x the price to USA or anyone else who wants it just like what China is doing. Clear as much old stock as possible. I'm sure there is a huge stock for this drug in India given the yearly malaria/dengue season. Nobody knows if this drug even works for Wuhan Virus so let the idiots take it at 10x price if they are hell bent on taking it.
Last edited by vimal on 07 Apr 2020 12:35, edited 1 time in total.

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 07 Apr 2020 10:42

Rahul M wrote:
DrRatnadip wrote:
To determine Exact efficacy of these drugs large study will be needed.. But in limited patients they seem to work fine.. Currently used protocol in all COVID positive pts in MH is as follows.:
1) asymptomatic but without comorbidities receive HCQ only
2) asymptomatic but with comorbidities receive HCQ and oseltamivir
3)symptomatic but those without comorbidities get Azithromycin in addition to above
4) symptomatic plus with comorbidities Lopinavir/ritonavir is added

Hello Doc, is this protocol devised by ICMR or someone else. Also, are treatment results being shared nationwide? For example are you getting info regarding how similar treatment regimes elsewhere in the country are doing?


This is protocol currently given by DMER.. Used in all medical colleges in maharashtra..

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Re: Wuhan Coronavirus Resource Thread

Postby Suraj » 07 Apr 2020 10:55

Image

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Re: Wuhan Coronavirus Resource Thread

Postby JayS » 07 Apr 2020 11:12

Rahul M wrote:https://www.mohfw.gov.in/pdf/3ContainmentPlanforLargeOutbreaksofCOVID19Final.pdf

The govts very detailed containment plan. This is the one coupta was talking about. It seems our administration is also rising to the challenge.


Rahul M, some of these documents are being released post facto i.e. the plan is already in place and even used in practice, the details are being released as and when wide-spread implementation is needed. The administration has risen long back. This document mentions the whole Strategic plane which is a 5-stage plan, strategic plan for each of the 5 stages of infection level. Though the document stops at 3rd stage while giving details. We know the some of the details of 5th stage i.e. endemic stage from the doc released for the 4-yr preparedness plan. 4th stage is when there is large scale outbreak. In such case no intervention policy would be effective in containment, so the govt plan is to drop all containment plan and focus on managing the peak and saving as much lives as possible. The strategic plan exists from the very beginning I think, and very likely even before this particular pandemic started as a strategic lessons learned from SARS/H1N1 outbreaks. The earliest I have seen it was on 3rd March. Everything is happening according to the plan.

Even this containment plan is nothing new, its already used in real life in multiple places in March itself, best example is Bhilwada, but there are at least 4-5 other districts too. This is an extension of the cluster management plan and a lot of the protocols from the cluster management are equally applicable for containment plan. Only difference is that the containment zone in case of cluster management was of 3km surrounded by buffer zone of 5km, and here the containment zone would be an administrative unit like a City, town or a whole district based on the spread of the infection and realistic boundaries which can be kept watertight for extended period.

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Re: Wuhan Coronavirus Resource Thread

Postby chola » 07 Apr 2020 11:58

vimal wrote:
g.sarkar wrote:_____________________________________________________________________________________________________________________
https://www.hindustantimes.com/world-ne ... 1bVQJ.html
Trump talks of ‘retaliation’ if India turns down anti-malarial drug request

Gautam


India should just export the malaria drug for 10x the price to USA like what China is doing and clear as much old stock cleared as possible. I'm sure there is a huge stock for this drug in India given the yearly malaria/dengue season. Nobody knows if this drug even works for Wuhan Virus so let the idiots take it at 10x price if they are hell bent on taking it.


https://www.news18.com/news/india/under-pressure-from-us-india-lifts-restrictions-on-24-drug-exports-amid-coronavirus-outbreak-2567403.html


NEWS18 » INDIA 1-MIN READ
[b]Under Pressure from US, India Lifts Restriction on 24 Drug Exports, Paracetamol Still on Restricted List
India had restricted the exports of 26 ingredients and medicines on March 3. Paracetamol and its formulations accounted for two items on the original list.



Hydroxychloroquine next? Or is this to reduce pressure on having to release hydroxychloroquine exports?

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Re: Wuhan Coronavirus Resource Thread

Postby syam » 07 Apr 2020 12:10

since when did the world start relying on indians for anything at all? we are those dirty third world people who shit on streets. great countries like amerikis shouldn't ask help from dirty curry indians.

we are not even their great allies anyway. are we expected to help them out or what? last year by this time, we were wondering if amerikis secretely helping pakis with sat-int. they invested their monies in wrong place. it's time they should get their dividends from said investments. modiji shouldn't give them anything more than the humanitarian amounts.

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 07 Apr 2020 12:17

Our babus have a habit of leaking policy circular to the press. They add masala to it, the jokers in other countries join in and we then scramble for an response.

India abviously would have allowed the export to needy countries. All GoI had to do was to announce the ban policy, along with criteria for countries to acquire these medicine from us.

MEA just announced this criteria, after the horse has bolted, allowing the press jokers to peddle these stories.

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Re: Wuhan Coronavirus Resource Thread

Postby Sachin » 07 Apr 2020 12:33


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Re: Wuhan Coronavirus Resource Thread

Postby srin » 07 Apr 2020 12:46

I saw some discussions on herd immunity and I'm a bit confused.

Absent a vaccine, it seems the way to get immunity is to get infected first and recover from it. So, the question is: if someone is infected and recovers, does that confer immunity to covid-19 (like in chickenpox) against re-infection ?


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