https://www.nytimes.com/2020/11/09/heal ... fizer.htmlPfizer’s Early Data Shows Vaccine Is More Than 90% Effective
Pfizer announced positive early results from its coronavirus vaccine trial, cementing the lead in a frenzied global race that has unfolded at record-breaking speed.
By Katie Thomas, David Gelles and Carl Zimmer
The drug maker Pfizer announced on Monday that an early analysis of its coronavirus vaccine trial suggested the vaccine was robustly effective in preventing Covid-19, a promising development as the world has waited anxiously for any positive news about a pandemic that has killed more than 1.2 million people.
Pfizer, which developed the vaccine with the German drugmaker BioNTech, released only sparse details from its clinical trial, based on the first formal review of the data by an outside panel of experts.
The company said that the analysis found that the vaccine was more than 90 percent effective in preventing the disease among trial volunteers who had no evidence of prior coronavirus infection. If the results hold up, that level of protection would put it on par with highly effective childhood vaccines for diseases such as measles. No serious safety concerns have been observed, the company said.
Pfizer plans to ask the Food and Drug Administration for emergency authorization of the two-dose vaccine later this month, after it has collected the recommended two months of safety data. By the end of the year it will have manufactured enough doses to immunize 15 million to 20 million people, company executives have said.
“This is a historical moment,” said Kathrin Jansen, a senior vice president and the head of vaccine research and development at Pfizer. “This was a devastating situation, a pandemic, and we have embarked on a path and a goal that nobody ever has achieved — to come up with a vaccine within a year.”
The news comes just days after Joseph R. Biden Jr. clinched a victory over President Trump in the presidential election. Mr. Trump had repeatedly hinted a vaccine would be ready before Election Day, Nov. 3. This fall, Pfizer’s chief executive, Dr. Albert Bourla, frequently claimed that the company could have some indication of whether the vaccine worked by October, something that did not come to p ass.
___________________________________________________________________________________________________________https://www.bbc.com/news/world-asia-china-54883383Coronavirus: China Sinovac vaccine trial halted in Brazil
The Brazilian clinical trial for a high-profile Chinese Covid-19 vaccine has been suspended after health authorities reported a "severe adverse" incident.
Brazilian health regulator Anvisa said it took place on 29 October, but did not give further details.
The Sinovac vaccine is one of several vaccines in final-stage testing.
But China has already been using it to immunise thousands of people in an emergency use programme.
There was no immediate response from Sinovac.
On Monday Anvisa said it had "ruled to interrupt the clinical trial of the CoronaVac vaccine after a serious adverse incident".
It did not reveal what happened, nor where it took place. Late-stage trials for the Sinovac vaccine are also being conducted in Indonesia and Turkey, but neither of these countries have announced a suspension.
Dimas Covas, the head of Butantan, the medical research institute conducting the Brazilian trial, told local media that the trial's suspension was related to a death.
But he insisted that the death was not related to the vaccine, reported Reuters news agency.
Butantan has said it would hold a news conference on Tuesday at 11am local time (1400 GMT).