Wuhan Coronavirus Resource Thread

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niran
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Re: Wuhan Coronavirus Resource Thread

Postby niran » 19 Apr 2020 16:39

Mollick.R wrote:What's wrong with mother Russia ???

They were doing pretty good initially. Grandmaster Putin closed China border, strict enforcement of law of (bear) land.
But current stat is 32008 Infected & 273 deaths.
Vast geographically spread out nation, still 32k in the early stage (as such it begin later there) is a bigggg number.


Israel also, considering total population, small size and military discipline of Yehudii desh they do have quite high numbers (12855 & 148).

Rodina even current day suffers from Pulmonary Tuberculosis epidemic, fried Aloo, boiled Aloo, smashed Aloo, tossed Aloo, roasted Aloo and Aloo ka Daru leads to malnurishment in turn lead to poor health and disease

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Re: Wuhan Coronavirus Resource Thread

Postby g.sarkar » 19 Apr 2020 17:30

https://www.npr.org/2020/04/17/83714145 ... s-hit-hard
Thousands Of Cars Line Up At One Texas Food Bank As Job Losses Hit Hard
John Burnett, April 17, 20204

Ten thousand cars waited hours in line for emergency food aid in San Antonio last week. A drone photograph of the packed parking lot went viral. Two thousand more showed up for another distribution today."We stock refrigerated, frozen and nonperishable food items so it moves through our facility at a fairly rapid pace," said food bank CEO Eric Cooper. "Obviously, now in the midst of COVID-19, the demand far outpaces the supply."
In addition to feeding the hungry in this city of more than 2 million souls, the food bank supplies 500 food pantries throughout South Texas. In a normal week, the food bank feeds about 60,000 people in its region. Today, that number has doubled.
ECONOMY
Lines At Food Banks Grow Longer By The Week
Last week, they knew they'd be busy. A record 6,000 families had preregistered for food distribution at a flea market parking lot. When word got out on social media, 4,000 more cars showed up.
"I panicked. I've never seen a line that long," Cooper said. "So I called our warehouse to send more trucks, to get more food on site. But we, in the end, served 10,000 families."
These were some of the more than 20 million unemployed Americans, many of them recently laid off because of the pandemic.
The San Antonio Food Bank operates a huge, 200,000-square-foot warehouse on the outskirts of the city. It is stacked four stories high with apples, oranges and watermelons; potatoes, tomatoes and onions; chicken, ground beef and tater tots.
A quartet of forklifts—working like soldier ants—fills a truck with pallets of carrots, while the boss watches.
.....
Gautam
Farmers are throwing away milk and vegetables as there is no way to donate perishables to the poor and recently unemployed.

g.sarkar
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Re: Wuhan Coronavirus Resource Thread

Postby g.sarkar » 19 Apr 2020 17:35

https://www.businessinsider.com/more-th ... rus-2020-4
After one month of coronavirus lockdown, more than 50% of Los Angeles is now unemployed
Tom Murray Apr 18, 2020

More than half of the population of Los Angeles are now unemployed, according to a national survey from the USC Dornsife Center for Economic and Social Research.
Researchers found that only 45% of LA workers are still employed, compared with 61% in mid-March as 1.3 million people have lost their jobs during the coronavirus crisis.
"In LA, there was a certain level of insecurity to begin with, and it has increased a little bit more than it has in the national average," USC's Jill Darling, survey director for the Understanding America Study, said according to LAist.
The research also found that ethnic minorities had been hit hardest by job losses across the country, with 15% of white people saying they had lost their jobs, while 18% of Latinos and 21% of black people reported job losses.
"Under normal circumstances losing a job without access to benefits would be bad enough, but in the current situation, chances of finding a new job are likely to be close to nonexistent," Arie Kapteyn, director of the USC Dornsife Center for Economic and Social Research, said in a statement seen by the LA Times.
......
Gautam

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Re: Wuhan Coronavirus Resource Thread

Postby srai » 19 Apr 2020 17:38

Rahul M wrote:https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes#

How covid works and why it is not the flu.

Great article!

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Re: Wuhan Coronavirus Resource Thread

Postby shaun » 19 Apr 2020 18:05

https://m.economictimes.com/news/scienc ... 224904.cms


Can coronavirus crisis change Indian science for good?
It's unlike software. Vaccines, drugs and medical devices cannot be churned out overnight.
By Malini Goyal & Ishani Duttagupta, ET Bureau | Updated: Apr 19, 2020, 09.43 AM IST



Covid-19 has brought India to a halt.
But for Anita Gupta, it has kicked off a frenetic race against time. For the bureaucrat — the associate head of innovation and entrepreneurship, Department of Science and Technology (DST), Government of India — the day typically begins at 6 am and ends well past midnight. “I am working two shifts,” she says.

Part of the government task force and its empowered committees on Covid-19, Gupta is in the thick of things. Her phone is constantly buzzing with messages from the 15-odd WhatsApp groups related to Covid-19 coordination that she is part of. There are messages flying back and forth in groups comprising elite scientists, IITians, startup founders, top corporate executives, doctors, prominent members of the Indian diaspora and bureaucrats.
Keeping a finger on the pulse of the dynamic demand and supply situation of things as varied as personal protective equipment (PPE), testing kits, ventilators and isolation wards, she taps and connects multiple networks on her phone, in a fascinating, multifaceted, behind-the-scenes race underway to combat India’s Covid-19 crisis, which has drawn in state as well as private sector capabilities.


Recently, a new, 40-bed Covid-19 hospital in Varanasi was grappling with a problem: how to design its AC network overnight amid the lockdown. For Covid-19 patients, centralised air conditioning cannot be used, as the virus could spread to other rooms through the ducts. Gupta flagged the problem on her WhatsApp groups. “Within 20 minutes, we had three good solutions, with experts offering to help design its AC layout,” she says.

Like other nations, India too is scurrying to build its own arsenal to fight the Covid-19 battle. From its network of labs, 150-odd incubators and other technology institutions, Gupta and her colleagues have picked 40 market-deployable solutions that will aid India’s fight. These include promising ideas from diagnostics technology to vaccines are being fast-tracked. “Decisions that earlier took months now happen real time,” she says.

On-the-spot decisions come backed with all necessary support such as funds, regulators’ approval and plant machinery to launch in the market. Recently, Nocca Robotics, a startup that makes robots that clean solar panels without water, figured it could pivot to making ventilators. Once startups are vetted and approved, DST plugs them into a network of suppliers and manufacturers to kickstart production.

Gautam Wankhede, cofounder of Mylab — the first Indian company whose testing kits received approval — echoes the view: “Once we got the ICMR (Indian Council of Medical Research) approval, the DCGI (Drugs Controller General of India) nod to start manufacturing came within 24 hours. The government has done a wonderful job in expediting decisions and helping us proactively.”
Covid Warriors
India is at war with an invisible enemy. Deaths are rising. Infections are growing. A panicstricken nation has locked down its billionplus people to halt the enemy. Meanwhile, India’s R&D labs have turned into war rooms where scientists are the generals leading the charge, working round the clock to build its weapons. And a growing battalion of Covid warriors — from bureaucrats such as Gupta to doctor-turned-entrepreneurs such as Wankhede, from regulators such as DCGI and ICMR to corporations such as Tata and Mahindra — are all joining forces to strengthen India’s fight. “I see a very positive reset happening.
lab4
Be it in making vaccines or handling biological samples, everyone is rallying to figure out how they can contribute,” says Manish Diwan, strategic partnership entrepreneurship development, Biotech Industry Research assistance Council (BIRAC). Set up in 2012, BIRAC, with its 50-odd incubators with visibility over 3,225 biotech startups, is playing a critical role.
Sitting in Delhi, on the world-class campus of Institute of Genomics and Integrative Biology (IGIB), director Anurag Agrawal, a pulmonologist, is gearing up for this battle. “This is the biggest challenge of our lives,” he says. The problem is huge. The pressure to solve it fast is immense, he admits. “You realise how big the enemy is and how inadequate India’s weapons are. And that we are responsible for equipping our army. As a scientist, you want to make yourself relevant,” he says over the phone.
IGIB, which has done human genome sequencing, has been able to quickly sequence the virus and is now collaborating with a range of outfits, from national bodies such as ICMR and NCDC (National Centre for Disease Control) to multinational corporations such as Intel, to study the human-virus interaction, how they are responding to different drugs, and to aid in deciding the drugs prescribed for patients.

IGIB has also developed a new paper strip-based Covid-19 test that uses CRISPR-Cas9 technology. With pilots underway, the test does not require expensive machines or trained technicians and can be deployed at point-of-care. Two Bengali scientists who led the development — Dr Souvik Maiti and Dr Debojyoti Chakraborty — have named it Feluda, after the beloved fictional detective created by Satyajit Ray.
Based out of Pune, V Premnath, head of bio-incubator Venture Center and NCL Lab, also finds himself at the heart of the resistance against the virus. His institution nurtures more than 75 startups (including Mylab) with 350 scientists. At least 25 startups at the Venture Center are looking to solve some of the Covid-19 related problems, many of them repurposing overnight. One of the incubatees was working on a technology to disinfect sanitary napkin waste.
Now they are looking at disinfecting PPE. How can one reuse N-95 masks? Can biosurfactants, used to prolong the life of fruits and vegetables, be used as a disinfectant for the virus? These are among the questions being tackled at the institution. Amid the crisis, he is loosening government controls on its patents.
lab7
“We are trying to be generous with some noncritical patents like those for PPE, gloves and masks. The country needs them now,” he says. The government is mounting an all-out effort to seek everyone’s help. “The government needs quick results. It reached out to us to shortlist medtech startups and solutions for a fast-track review and scaling up,” says S Balram, CEO, Technology Business Incubator for Medical Devices & Biomaterials (TiMED) at the biomedical technology campus of Sri Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram.
It offered a Rs 10 lakh grant to Avatar Renewables for developing a thermal scanner integrated with metal detectors, which can be used to screen body temperature in crowded spaces such as airports. Aerobiosys, incubated at the Center for Healthcare Entrepreneurship (CfHE), Hyderabad, has developed low-cost portable ventilator Jeevan Lite and is now ramping up production. At IITBombay, Biomedical Engineering & Technology Innovation Centre (BETIC) incubatee Ayu Devices has developed AyuSynk for remote auscultation (listening to chest sounds), which helps doctors treat Covid-19 patients and maintain records remotely.
Siraj Dhanani, founder, InnAccel Technologies, has developed two products — VAPCare and Saans Pro — which are being used for Covid-19 patients. IIT-Madras’ Healthcare Technology Innovation Centre has incubated Ubiqare Health, which provides telemedicine solution for clinical telepresence technology and is useful for remote treatment of Covid-19 patients. Another of its incubatees, zBliss Technologies, has built an ICU automation platform solution to monitor Covid-19 patients in isolated units.
Large corporations such as M&M, Tata, Hyundai and stateowned Bharat Electronics are joining forces. They are reconfiguring their plants to make products such as ventilators. Maruti Suzuki, which has a deep vendor network, is partnering with ventilator maker AgVa to scale up its manufacturing.
lab9
There are also prizes being instituted to incentivise innovation. There is a lot of thrust on startups. The government has launched Covid-19 Solution Challenge for startups, with a relatively modest prize money of Rs 1 lakh and the opportunity to see the product being supported for scale-up.
Marico Innovation Foundation and ATE Chandra Foundation have announced a Rs 2.5 crore grant for medtech innovators. Nandan Nilekani and other entrepreneurs have joined hands with investors such as Sequoia and Accel to set up a Rs 100 crore ACT Grant to give wings to ideas that could combat Covid-19. “Beyond the seed grant, additional scale capital could come from other platform partnerships we are building,” says Prashanth Prakash, founding partner, Accel. It has received over 1,000 ideas and offered grants to 20 already.
The big push comes amid a slew of challenges. The biggest is building a supply base from scratch during a national and global lockdowns. “70-90 per cent of our critical medical device components and chemical reagents were being imported. Overnight, they have stopped,” says Diwan of BIRAC. This has pushed the government for a strategic, longterm rethink on building local manufacturing capacities. After the first medtech zone (MTZ) in Visakhapatnam early this year, the government has cleared the way for four more MTZs.
Agrawal of IGIB says many ingredients of its paper strip-based CRISPR test for Covid-19 came from countries such as China and Germany. Similarly, sealing tapes for PPE were being sourced from China. All these supplies have been disrupted. Multiple stakeholder committees formed by the government, drawing people from different areas — from regulators to large companies, startups to scientists and R&D labs — are helping develop an alternate vendor base.
lab11
For example, Defence Research and Development Organisation (DRDO) had developed an in-house glue for applications in submarines, which is now being used in PPE. “Industry, with their knowledge of India’s vendor landscape, is helping us in a big way in building component supply base from scratch,” says Agrawal.
Wankhede says for a startup like Mylab, among the earliest challenges was to get real virus sample to conduct testing validation. They had to first work with synthetic samples. As countries block exports, he has had to not just develop a local vendor base but also replace reagents with substitutes more easily available in India to scale up overnight.
Chandrasekhar Nair of Bigtec Labs, whose company Molbio is making testing kits, says his biggest challenge is that in a lockdown, he is short on staff to undertake manufacturing. “The government is helping to sort out the problem,” he says.
lab12
Beyond these immediate constraints, India’s biosciences landscape faces other structural issues like lack of patient venture capital and poor connect between demand and supply. That is why InnAccel, a medtech company, abandoned its plans of becoming a private sector incubator to build its patented products. Due to multiple testing and stringent regulatory requirements, the lab-to-market journey is long and arduous. InnAccel founder Siraj Dhanani hopes Covid-19 crisis will now crunch the timeline.
Srinivas Madhusudan, head of Medtech & Geriatric Healthcare Technology Business Incubator at Indian Institute of Science (IISc), Bengaluru, offers another view: “India’s medtech startups often start on a solid intellectual platform but (later) quality standards get neglected, which is the reason for failure.” To scale up commercially, he says, Indian devices will need to meet quality norms of countries like the US and regions like the EU.
But the worst is getting manufacturing logistics in place. “Even after having a manufacture-ready prototype and a good business plan, the main challenges that healthcare startups face are in manufacturing and marketing,” says Renu John, faculty co-head, CfHE, at IIT-Hyderabad.
That’s where the one-year-old Andhra Pradesh MedTech Zone (AMTZ) in Visakhapatnam can perhaps help in a big way.
Headed by MD Jitendar Sharma, AMTZ is a one-stop facility with 18 high-end testing labs. Sharma says it is the world’s first such facility that allows someone to build a prototype as well as manufacture high-end devices such as CT scanners and MRI machines, all under one roof. “India spends Rs 50,000 crore annually, importing 80 per cent of its medical devices’ requirement. AMTZ aspires to change that,” says Sharma. By 2020-end, he hopes AMTZ will substitute at least 10 per cent — or Rs 5,000 crore — of imports.
Chasing the Covid-19 crisis, AMTZ — spread over 8 sq km, with two incubators and 55 startups — is now humming round the clock, scaling up overnight to make products such as PPE and ventilators that India desperately needs. They began making ventilators 10 days ago and can now make 200 units daily. AMTZ started making Molbio RT-PCR diagnostic kits just 15 days ago. From 2,000 testing kits daily, it has now scaled up to 25,000. More products like thermal scanners and mobile bus for Covid-19 testing are in the pipeline. “Because the capex was funded by the government and we offer a ready-made factory, manufacturing can begin over night at costs at least 40 per cent lower than the outside,” he says.
Never Waste a Crisis
Covid-19 crisis can potentially reinvigorate and transform India’s scientific landscape. That hope is exciting for scientists. For a long time, India’s scientific pursuits have been hobbled by multiple qualitative and quantitative issues. India’s R&D spend is largely driven by the government (60 per cent). While India’s GERD or gross expenditure on R&D, has grown from Rs 47,353 crore in 2008-09 to Rs 1,04,864 crore in 2017-18, as a percentage of GDP it remains flat at 0.6-0.7 per cent as against the US’ 2.8 per cent, Korea’s 4.2 per cent and China’s 2.1 per cent.
Last year, a report by the Economic Advisory Council to the Prime Minister set a target of 2 per cent of GDP by 2022. Qualitatively, India fares poorly. Based on number of publications, their citations and patents filed — good indices of top-grade research and innovation — India ranks far behind others, such as China and the US.
“Our R&D is marked by ‘me too’ research and has limited capacity to absorb investment,” says Shailja Vaidya Gupta, senior adviser, office of the principal scientific adviser, Government of India. Many of our top science labs are bureaucratic and operate in silos divorced from India’s needs and realities. Applying lab research and innovation to solve India’s problems is often missing. “This is a wake-up call for everyone. We need to reinvent. We cannot do business as usual. I am quite optimistic. With this crisis, we are beginning to break silos and collaborate to find solutions,” she says.
A new inter-disciplinary, collaborative culture is taking root. Premnath is the coordinator of a task force looking at repurposing drugs. It has an advisory group of 20 people, including scientists, virologists, immunologists, regulators and industry executives. All of them are working together with the sole purpose of finding solutions and the quickest route to manufacturing them.
“The pace is remarkable. We have looked at 20 molecules in the last two weeks. Unimaginable in the normal scenario,” he says.
Urgency has also meant that merit is beginning to get precedence over hierarchy protocols. Instead of institute’s director bureaucratically rolling down decisions, relevant scientists are being enlisted directly on critical projects.
“With a crisis as big as this, everyone is being tested. Some are getting exposed while many under the radar are getting noticed for their sharpness,” says Premnath.
This is also bringing science closer to India’s problems. “Science in the lab must be applied to solving problems outside. This is happening now,” says Taslimarif Saiyed, director of biotech incubator C-CAMP.
The crisis is forcing a strategic rethink within the government on how it nurtures its scientific landscape. There is a realisation that instead of importing, creating indigenous knowledge and manufacturing base should be national priority. Unlike software, vaccines, drugs and medical devices can’t be churned out overnight. Fortunately, India, with its CSIR labs and outfits like BIRAC, has built a strong bio science foundation with a robust startup and corporate base. Serum Institute of India is the world’s largest vaccine manufacturer. India’s pharma companies dominate the world’s generic drug business.
What we need is some hustle, collaboration and urgency to fight the Covid-19 battle. “In a way, this crisis has catalysed India and its scientific community. There is hope it will reflect in budget allocation,” says Diwan.

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Re: Wuhan Coronavirus Resource Thread

Postby Sanju » 19 Apr 2020 19:56

Rsingh ji, Praying for you and hoping for a successful procedure & speedy recovery.

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 19 Apr 2020 20:01

Sweden could have 'herd immunity' by next month, claims its infectious diseases chief amid row over its rising deaths and relaxed lockdown measures

Published: 11:00 BST, 19 April 2020 | Updated: 14:42 BST, 19 April 2020

Parts of Sweden could achieve 'herd immunity' as early as next month, the country's leading epidemiologist has said as the death toll rises.

The Government is holding out against a total lockdown despite growing calls for 'rapid and radical measures' to contain the coronavirus outbreak.

It has cancelled football games and closed university buildings. Restaurants, cinemas, gyms, pubs, and shops remain open.

Last week, it announced plans for an aggressive testing regime which could see 100,000 tests administered as the number of cases exceeded 13,000.

Speaking to local media, Dr Anders Tegnell, the architect of Sweden's controversial strategy, claimed that the population of Stockholm - the epicentre of the country's outbreak - could achieve 'herd immunity' as early as next month. [..]

Dr Tegnell said: 'According to our modellers [at the Public Health Agency of Sweden], we are starting to see so many immune people in the population in Stockholm that it is starting to have an effect on the spread of the infection.

'Our models point to some time in May.'

He told Norwegian TV: 'These are mathematical models, they're only as good as the data we put into them. We will see if they are right.'

Dr Tegnell's assessment came after the national death toll was recorded at 1,511, with 13,822 confirmed cases.

Asked about the death rate, Dr Tegnell said: 'It is not a failure for the overall strategy, but it is a failure to protect our elderly who live in care homes.'

Sweden has been described as an 'outlier' as it refuses to impose an EU-style lockdown, despite its coronavirus-related death rate rising.

Currently around 50 per cent of the Swedish workforce is working from home, while public transport has fallen by 50 per cent in Stockholm. The capital is around 70 per cent less busy.

However, Swedes can still go shopping, eat out at restaurants, get haircuts, and send children younger than 16 to class - even if a family member is ill.

The Government has faced rising criticism of its policy, as detractors point to the rising death toll as proof that its aversion to total lockdown is misguided. [..]

Some of the country's top epidemiologists hit out at the Public Health Agency of Sweden, claiming it and the Government was 'not at all prepared' for a pandemic.

'The authorities and the Government stupidly did not believe that the epidemic would reach Sweden at all,' Bo Lundback, a professor of epidemiology at the University of Gothenburg, alleged this week.

Prof Lundback and 21 other researchers urged the Government to reconsider and institute 'rapid and radical measures' in a joint article in Dagens Nyheter newspaper.

'Sweden was poorly or even not at all prepared,' Prof Lundback added.

But officials insist their plan is sustainable in the long-term, rejecting drastic short-term measures as too ineffective to justify their impact on society.

Dr Tegnell has defended his limited interventions, telling The Mail on Sunday that he believed that Britain's lockdown had gone too far. [..]

He told the paper that Sweden was 'following' the UK's original approach of resisting lockdown, and was 'disappointed' by Britain's abrupt U-turn.

'I am very sceptical of lockdowns altogether but if you ever do them, you should do them at an early stage,' Dr Tegnell claimed.

He added: 'So far, what we are doing is working. In a sense we are beating it, and I am confident we are doing the best we can in the circumstances.'

Dr Tegnell has described the virus as a manageable risk, saying: 'I still go to restaurants. We can't kill all our services.

'And unemployed people are a great threat to public health.

'It's a factor you need to think about.'

Sweden's economy is also projected to shrink by as much as 10 per cent as the world economy grinds to a standstill - despite remaining mostly 'open'.

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Re: Wuhan Coronavirus Resource Thread

Postby pgbhat » 19 Apr 2020 20:08

madhu wrote:I think we need to observe sweden carefully. They are doing completely different from rest of the world. This is in line with what jayprakash is telling.

Swedish expert: why lockdowns are the wrong policy
UK policy on lockdown and other European countries are not evidence-based
The correct policy is to protect the old and the frail only
This will eventually lead to herd immunity as a “by-product”


All epidemics end with either herd immunity or vaccination.The question is how do you ensure staggered herd immunity across population such that hospitals don't get overwhelmed with patients like Italy and NYC? Also is herd immunity long lasting? Flu certainly returns every year, but its rate of infection (even after flu vaccines....may be because they don't cover all flu viruses) is no where near SARS-COV-2. The point is that so little is known about long term impact of the virus on human body. One should not "plan" for "herd immunity" but manage hospitalization rate while working on vaccination and treatment.

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Re: Wuhan Coronavirus Resource Thread

Postby SBajwa » 19 Apr 2020 20:37

Rsingh hi,

Praying for you . Never ever forget Chardhi Kala aka always be positive.

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Re: Wuhan Coronavirus Resource Thread

Postby putnanja » 19 Apr 2020 22:03

Corona virus can attach to kidney cells too, and other organs , and affect them says this study, not just lungs.

Coronavirus destroys lungs. But doctors are finding its damage in kidneys, hearts and elsewhere.

...
But clinicians around the world are seeing evidence that suggests the virus also may be causing heart inflammation, acute kidney disease, neurological malfunction, blood clots, intestinal damage and liver problems. That development has complicated treatment for the most severe cases of covid-19, the illness caused by the virus, and makes the course of recovery less certain, they said.

The prevalence of these effects is too great to attribute them solely to the “cytokine storm,” a powerful immune-system response that attacks the body, causing severe damage, doctors and researchers said.

Almost half the people hospitalized because of covid-19 have blood or protein in their urine, indicating early damage to their kidneys, said Alan Kliger, a Yale University School of Medicine nephrologist who co-chairs a task force assisting dialysis patients who have covid-19.

Even more alarming, he added, is early data that shows 14 to 30 percent of intensive-care patients in New York and Wuhan, China – birthplace of the pandemic – have lost kidney function and require dialysis, or its in-hospital cousin, continuous renal replacement therapy.
...
Still, when researchers in Wuhan conducted autopsies on people who died of covid-19, they found nine of 26 had acute kidney injuries and seven had particles of the coronavirus in their kidneys, according to a paper by the Wuhan scientists published April 9 in the medical journal Kidney International.

“It does raise the very clear suspicion that at least a part of the acute kidney injury that we’re seeing is resulting from direct viral involvement of the kidney, which is distinct from what was seen in the SARS outbreak in 2002,” said Paul Palevsky, a University of Pittsburgh School of Medicine nephrologist and president-elect of the National Kidney Foundation.
...
The new virus enters the cells of people who are infected by latching onto the ACE2 receptor on cell surfaces. It unquestionably attacks the cells in the respiratory tract, but there is increasing suspicion that it is using the same doorway to enter other cells. The gastrointestinal tract, for instance, contains 100 times more of these receptors than other parts of the body, and its surface area is enormous.
...
The virus also is having a clear impact on the gastrointestinal tract, causing diarrhea, vomiting and other symptoms. One study found that half of covid-19 patients have gastrointestinal symptoms, and specialists have coined a Twitter hashtag, #NotJustCough, to raise awareness of them.
...
Reports also indicate that the virus can attack the liver. A 59-year-old woman in Long Island came to the hospital with dark urine, which was ultimately found to be caused by acute hepatitis. After she developed a cough, physicians attributed the liver damage to a covid-19 infection.

Spiegel said he has seen more such reports every day, including one from China on five patients with acute viral hepatitis.
...

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Re: Wuhan Coronavirus Resource Thread

Postby amar_p » 19 Apr 2020 22:18

I wonder what is Center for Cellular and Molecular Biology ( CCMB ) in Hyderabad is doing. Apart from being a Covid testing center they don't seem to be doing much going by their web site (which is also seriously old tech by the way).

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 19 Apr 2020 22:39

rsingh pindiwale, get well soon.
Our best wishes are with you.

amar_p wrote:I wonder what is Center for Cellular and Molecular Biology ( CCMB ) in Hyderabad is doing. Apart from being a Covid testing center they don't seem to be doing much going by their web site (which is also seriously old tech by the way).
in addition to tests round the clock they are doing research into both vaccines and cure. Both original work and selecting best candidates from worldwide research.

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 19 Apr 2020 22:44

putnanja wrote:Corona virus can attach to kidney cells too, and other organs , and affect them says this study, not just lungs.

This disease seriously is getting scarier day by day...gotta thank Chinese & WHO for this mess.

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Re: Wuhan Coronavirus Resource Thread

Postby pankajs » 20 Apr 2020 01:30

https://twitter.com/iMac_too/status/1251726858367819776
iMac_too @iMac_too

Kerala: Several test positive after quarantine for four weeks


Also, https://twitter.com/ShamikaRavi/status/ ... 2774671370
Prof Shamika Ravi @ShamikaRavi

#DailyUpdate #Covid19India
The growth rate is declining consistently in India. The growth of Active cases in last 5 days is 6.6% - so doubling every 11 days.

Image

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Re: Wuhan Coronavirus Resource Thread

Postby Mollick.R » 20 Apr 2020 01:59

Coronavirus live updates:
(FROM TIMES OF INDIA)

Telangana extends lockdown till May 7; no relaxation in Punjab, Delhi
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Accordingly, a total of 16 regional depots are being set up and are modelled into self-contained units by strengthening manpower, resources and infrastructure: ICMR

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The daily Covid-19 testing capacity at various laboratories in the country is being increased and is expected to reach to 1 lakh test per day by May 31: Indian Council of Medical Research
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Pune Municipal Corporation has passed an order to declare the complete area under the jurisdiction of Pune Municipal Corporation a Containment Zone, from today midnight till April 27
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French health minister Olivier Véran thanks India for allowing exports of medicines to France to treat critically ill patients. He had a long discussion with Dr Harsh Vardhan on Friday April 17: French government sources



https://timesofindia.indiatimes.com/india/coronavirus-in-india-live-news-updates-indias-count-crosses-15000-toll-over-500/liveblog/75228082.cms

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Re: Wuhan Coronavirus Resource Thread

Postby madhu » 20 Apr 2020 03:10

Viet Nam shows how you can contain COVID-19 with limited resources


To date, Viet Nam has had no fatalities as a result of the pandemic.
The government acted swiftly to suspend flights, shut schools and quarantine new arrivals.
More than 45 million Vietnamese have been lifted out of poverty between 2002 and 2018.

Its anti-coronavirus measures have gone on to include mandatory 14-day quarantines for anyone arriving in Viet Nam and the cancellation of all foreign flights. It has also isolated infected people and then set about tracking down anyone they might have come into contact with.

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Re: Wuhan Coronavirus Resource Thread

Postby Santosh » 20 Apr 2020 03:30

Pak ad BD are starving their Hindu minorities amid Covid-19 pandemic
https://www.opindia.com/2020/04/pakista ... -pandemic/

Madhya Pradesh: Sanitation workers attacked by a mob with axes, rods and sticks, one worker badly injured, main accused Adil arrested
https://www.opindia.com/2020/04/madhya- ... uslim-mob/

Medicines being bought secretly, treatment being done at home: The mystery behind Indore’s steep rise of dead bodies in Muslim graveyards deepens
https://www.opindia.com/2020/04/indore- ... -secretly/

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 20 Apr 2020 03:38

Why do the muslims wan't to get treated secretly when then can get free and better care from the govt, unless there is much more sinister that they are trying to hide. This is getting scary.
Last edited by hanumadu on 20 Apr 2020 03:44, edited 1 time in total.

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Re: Wuhan Coronavirus Resource Thread

Postby rsingh » 20 Apr 2020 03:40

pankajs wrote:https://twitter.com/iMac_too/status/1251726858367819776
iMac_too @iMac_too

Kerala: Several test positive after quarantine for four weeks


It indicates that quarantine was NOT maintained. JMT
Thanks guys for your moral support. Means lot to me.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 20 Apr 2020 03:43

madhu wrote:Viet Nam shows how you can contain COVID-19 with limited resources


To date, Viet Nam has had no fatalities as a result of the pandemic.
The government acted swiftly to suspend flights, shut schools and quarantine new arrivals.
More than 45 million Vietnamese have been lifted out of poverty between 2002 and 2018.

Its anti-coronavirus measures have gone on to include mandatory 14-day quarantines for anyone arriving in Viet Nam and the cancellation of all foreign flights. It has also isolated infected people and then set about tracking down anyone they might have come into contact with.


India has been doing pretty much everything Vietnam has done, yet Vietnam has been unbelievably successful. I wonder if there are other factors specific to Vietnam to see such low infection rate. Of course India has to contend with the jaahil TJ and 15 lakh foreign returnees. Even accounting for it, the number of cases in Vietnam are simply too low considering it has a steady flow of tourists.

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Re: Wuhan Coronavirus Resource Thread

Postby vera_k » 20 Apr 2020 05:04

^
Do not think resources were limited here. On a per capita basis, Vietnam has been testing 10x the number of people. That would have increased the ability to break the transmission chain sooner.

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Re: Wuhan Coronavirus Resource Thread

Postby Gerard » 20 Apr 2020 05:38

The American aircraft carrier Theodore Roosevelt made a port call in Vietnam. The crew was given shore leave. After they left Da Nang....

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Re: Wuhan Coronavirus Resource Thread

Postby Cain Marko » 20 Apr 2020 06:26

WB is a real concern especially considering the with border with BD. Now with another congregation of 50k in BD, this could be a real problem. If 9k tablighis caused so much havoc in A country like desh, with it's massive geography, I wonder whats in store for bd. And that stupid WB govt. could really eff this up for everybody. Hope GOI is thinking of a plan to prevent major disaster.

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Re: Wuhan Coronavirus Resource Thread

Postby vera_k » 20 Apr 2020 06:38

^ That state has a large international airport too. IMO, there should be uniform guidelines on testing that states have to meet before their airports are allowed to operate passenger flights. That may perhaps be the best that can be done to get states to shape up.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 20 Apr 2020 08:11

All states bordering WB must strictly close the borders.

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Re: Wuhan Coronavirus Resource Thread

Postby pgbhat » 20 Apr 2020 08:45

hanumadu wrote:All states bordering WB must strictly close the borders.

And MP

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Re: Wuhan Coronavirus Resource Thread

Postby shaun » 20 Apr 2020 11:11

Total testing is 4 Lacs in India and Bengal have done only 5K tests so far. With such a low sample , they have started complaining about alleged defective kits supplied . Problem is NICED have flagged a week back ,about the low number of tests recently, to which The WB CS have alleged that the institute can only test 100 samples per day !! Which seems to be untrue, NICED being a regional virology center. It is understanable that NICED now will be targeted , first for low number of tests and now for faulty kits . wbdhfw have tweeted , "There was no problem earlier when the testing kits were being received directly from National Institute of Virology, Pune. Recently, the supplies to Government Labs in West Bengal have been routed through ICMR-NICED, Kolkata" . But what we know , all the testing kits be it from VIR Pune , are supplied to WB, is routed through NICED . There seems to be a campaign to malign NICED . Is there any precedent now in India of faulty testing kits .

https://www.ndtv.com/india-news/coronav ... mr-2214619

More over Odisha have same level of infrastructure if not low but with a less population base compare to WB but they have done approx 10k sample tests . There are some unauthenticated report circulating in WhatsApp from Doctors in Kolkata that estimated asymptomatic cases are in thousands .

updates
“Earlier when kits were required in smaller quantities they were imported, standardised and then distributed by NIV, Pune. But when the demand started rising ICMR imported the kits and sent them directly to the 16 regional hubs, including NICED, in Kolkata. The kits were then distributed to state run medical colleges where they were required to be standardised. This standardisation is not being done because of lack of time and technical knowledge,” said Shanta Dutta, NICED director.

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Re: Wuhan Coronavirus Resource Thread

Postby yensoy » 20 Apr 2020 11:34

rsingh wrote:
pankajs wrote:https://twitter.com/iMac_too/status/1251726858367819776

It indicates that quarantine was NOT maintained. JMT
Thanks guys for your moral support. Means lot to me.

Not really. There could be undetected cases which ping-pong from person to person in the family for over 4 weeks.

There is really no exit with the expectation of zero cases. It is a myth that we can snuff this out entirely. The best we can do is to reach some number (which could be zero known cases) and be eternally vigilant and prepared for a breakout while testing randomly over the course of time.

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Re: Wuhan Coronavirus Resource Thread

Postby Bart S » 20 Apr 2020 13:10

Any idea what is happening in GJ? 367 yesterday, 277 the day before, and 100+ for several days before that.

Why the massive rise in cases over the last few days? Are they being hit by the single-source spread and only discovering the scale now? Or fallout from neighboring states like MP and Mah?

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Re: Wuhan Coronavirus Resource Thread

Postby SSridhar » 20 Apr 2020 13:46

There was a spurt in TN yesterday from the 30s to 105. The Health Secretary didn't conduct the usual press meet. It was a terse announcement instead. Don't know how much of it was 'from one source'.

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Re: Wuhan Coronavirus Resource Thread

Postby syam » 20 Apr 2020 14:02

the virus is extremely contagious. even brief lapse in containment can make many people infected.

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 20 Apr 2020 14:03

20.04.2020

*Press Release*

TamilNadu Govt Doctors Association (TNGDA) condoles the death of Dr Simon at Chennai due to Covid19 yesterday. He got infected when he unsuspectedly treated at patient.

TNGDA condemns the the action of unruly mob preventing the burial of Dr Simon yesterday. The TNGDA demands and regrets that this being the third such incident of problems with the burial of doctors, Govt should have provided adequate security. Tngda demands stern action against these persons under stringent acts.

The fact is the dead body packed is least infective and the ignorant mob agitating against decent burial needs very stern action. The treatment of even a mild Covid patient is several fold riskier for the HCPs. But still we do the same with dedication and responsibility.

Already the Govt sector is over burdened with Covid and NonCovid emergencies as most private sector institutions have downed their shutters. At this juncture such disheartening incidences will de-motivate the doctors and other HCPs. The TNGDA demands proper action against the perpetrators and protection in all unfortunate future incidents. Why only to Doctors? Is this the reward for our selfless commitment for the fight against the deadly SARS-COV2 virus?

TNGDA cautions the public about the situation if HCPs and other players in this anti-covid war starts thinking about their own safety by this heartless behaviour of certain group.

Govt doctors are risking their own lives with the available poor quality/inadequate protective gears in treating the patients.

Recently many doctors have become positive inspite of wearing protective gears. TNGDA demands supply of proper specified protective gears immediately to all HCPs doing Covid duties. All HCPs should be provided suitable isolated individual accommodation and supply of food and adequate quarantine to reduce the risk of spread during incubation/ asymptomatic period and to reduce the viral load.

Dr K Senthil
State President
TNGDA

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 20 Apr 2020 14:04

Dear all
Our closest friend Dr. Pradeep who was the doctor who drove the ambulance wearing the PPE and buried Dr. Simon with his own hands narrated the horrific inhuman act that happened yesterday.
The ambulance with the mortal remains was stopped in front of Ega theatre and the drivers were beaten up and also the ambulance damaged. Further the body was left in the middle of the road opposite to the theatre.
Following this our friend Dr. Pradeep begged for the help of ambulance drivers who were in no shape to drive. Hence he along with two ward boys drove to another cemetery and using only one spade which was available there personally dug the grove along with help of one another police, buried the body. He is so traumatised about burying his own colleague and friend and feels such a death should not occur to even our enemies.
This is the narrative of the event happened from the doctor who was in the frontline
This brings out the narrow minded nature of the public and I wonder where these patients will go if all hospitals do not want to treat the COVID patients
We are not God and we also are vulnerable to get the disease but we work inspite of all adverse situations to deserve only this treatment from the public. I don’t think medical profession is considered as noble anymore
Dr. Narmada
Secretary IMA Vellore

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 20 Apr 2020 14:10

Over 1400 cases during the past two days, significantly higher than the previous few days.

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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 20 Apr 2020 14:10

Two days back Doctor was beaten again in Malegaon civil hospital.. Doctors who die fighting COVID are our national heros.. If people are " protesting" against proper burial of our fallen heros , we might not get committed doctors to fight against corona.. Its highly demoralizing for entire healthcare workers risking their lives..

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 20 Apr 2020 14:16

Center has to deploy CPMF or send a stern circular to the states stating NSA will be applied or stringent law provisos against anyone attacking a medico during this crisis. :evil:

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Re: Wuhan Coronavirus Resource Thread

Postby SSridhar » 20 Apr 2020 14:34

DrRatnadip wrote:Dear all . . ..

That is so terrible and shameful.

I don't know how TN police allowed this to happen. May God bless Dr. Simon.

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Re: Wuhan Coronavirus Resource Thread

Postby Mukhi » 20 Apr 2020 14:38

Bart S wrote:Any idea what is happening in GJ? 367 yesterday, 277 the day before, and 100+ for several days before that.

Why the massive rise in cases over the last few days? Are they being hit by the single-source spread and only discovering the scale now? Or fallout from neighboring states like MP and Mah?



From What I am told, (Its a hearsay, so take it with a grain Of salt) The curfew is not being followed by the public, resulting in easy contamination. The GOV is not strict enough in enforcing the curfew. Plus, general belief among population is / was, that once temp goes above 40 C, Corona cases will go down. That is not the case. No data of source is available for GJ.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 20 Apr 2020 14:54

R Singh - get well soon, our prayers and best wishes for you.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 20 Apr 2020 14:54

SSridhar wrote:
DrRatnadip wrote:Dear all . . ..

That is so terrible and shameful.

I don't know how TN police allowed this to happen. May God bless Dr. Simon.


Horrific. Those people should all be booked under the most stringent laws. :x


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