Wuhan Coronavirus Resource Thread

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chola
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Re: Wuhan Coronavirus Resource Thread

Postby chola » 05 May 2020 02:04

^^^ Anmol ji! That was among the most brilliant posts in this thread.

Everyone should be made to wear masks!

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Re: Wuhan Coronavirus Resource Thread

Postby saip » 05 May 2020 02:49

We need that poster that should be posted outside all the retail stores.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 05 May 2020 02:54

saip wrote:Masks are NOT for protecting you from getting infected. May be N95 masks will offer SOME protection to you from getting infected but not surgical masks. Masks are meant to stop you from SPREADING infection to others. When you are not wearing a mask your breath carries the virus if you are infected a few feet but if you are wearing a mask your breath (and the virus in case you are carrying) will stop in less than a foot. If everyone wears a mask and maintains social distance then I am sure the infection will drop significantly. Two days back I was in Walmart and I noticed half of the people were NOT wearing masks. Even educated people can behave idiotically. Now Costco has imposed masks for everyone if you want to enter.


This is incorrect. They help in protecting you from infection and infecting others both. Please read the references given in the thread.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 05 May 2020 02:57

nvishal wrote:About to hit 3000 cases per day any day now

Testing is mostly only being done on people with symptoms and asymptotic people who came in contact with the positive cases

People wearing masks are contracting it and I now believe they offer minimum protection. If you're an exempted person travelling daily then it is just a matter of time before you contract it. You'll probably never know you had it.

Actual cases are probably several times higher and many of them have already developed antibodies.

There is still no answer as to why the virus prefers to attack some bodies while it skips others altogether.


Please dont spread FUD. What you believe or don't believe is not relevant.

The office of the PSA has put out data showing masks do help in reducing infection significantly with references. Read, don't misinform.

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Re: Wuhan Coronavirus Resource Thread

Postby srai » 05 May 2020 03:20

^^^

It’s what people do before/during/after wearing masks that makes a difference. People touch their faces all the time with or without mouth masks. (Face shield is probably better.) Then there is the question how people handle putting masks on and off. And then, most common people will reuse masks instead of disposal (as in one time use in hospitals). If reuse, how masks are handled and sanitized matters.

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 05 May 2020 03:23

Apparently this s being hailed as a major step (at least in Israeli Twitter circles)...

Israel's IIBR completes development phase of COVID-19 antibody

The Israel Institute for Biological Research (IIBR) has completed the development phase of COVID-19 antibody or passive vaccine, according to a statement by the Defense Ministry.

Defense Minister Naftali Bennett visited the Ness Ziona-based lab on Monday and was briefed by the research team, who revealed a breakthrough antibody that attacks the virus and neutralizes it in the body.

IIBR is now working to patent its antibody and secure a contract for its commercial development. All legal procedures will be coordinated with the Defense Ministry.

“I am proud of the Biological Institute staff, who have made a major breakthrough,” Bennett said Monday. “The Jewish creativity and ingenuity brought about this amazing achievement.”

Last month, IIBR announced that it had begun testing its antibody-based vaccine prototype on rodents.

IIBR is also involved in plasma collection from people who have recovered from infection with the new coronavirus, in the hope that this might help research.

A second Israeli research team, MigVax, has also reported that it is close to completing the first phase of development of a coronavirus vaccine. Last week, it secured a $12 million investment from OurCrowd to accelerate the path to clinical trials.

Good show by the Israelis...if IIBR is looking for contracts for commercial development, I hope GoI reaches out. We do have decent experience in manufacturing drugs in massive scale.

How long before a vaccine like above is certified for regular hospital use?

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 05 May 2020 03:29

srai wrote:^^^(Face shield is probably better.)

In India, any kind of PPE sale on e-commerce site is banned. So PPEs like face shields or even safety goggles are currently not available or not deliverable on Amazon, Flipkart etc.

I realize that PPEs first priority is for healthcare workers but when we are at a stage where we are coming out of lock down, I'd hoped that GoI would have made some of the PPEs, which could help in slowing down or preventing transmission, available to the public. Anyways, I will try inquiring at a couple of local pharmacies about availability of shields and/or goggles.

Surprisingly, safety goggles are available on Amazon US website. Read reviews where even nurses and other healthcare workers are buying these goggles on their own for daily use while treating Covid patients.

WHO has decent guidelines with animations & illustrations on how to wear & remove masks.

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Re: Wuhan Coronavirus Resource Thread

Postby srai » 05 May 2020 03:37

^^^
Personally, I find mouth mask very suffocating to wear for a long duration. I have this urge to constantly pull it down to get a breath of fresh air. That’s me though. Just instinct.

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Re: Wuhan Coronavirus Resource Thread

Postby Mort Walker » 05 May 2020 04:08

srai wrote:^^^
Personally, I find mouth mask very suffocating to wear for a long duration. I have this urge to constantly pull it down to get a breath of fresh air. That’s me though. Just instinct.


I went on travel in March and wore an N95 mask on a 3 hour flight. After 2 and 1/2 hours it was miserable. It was suffocating.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 05 May 2020 05:15

srai wrote:^^^

It’s what people do before/during/after wearing masks that makes a difference. People touch their faces all the time with or without mouth masks. (Face shield is probably better.) Then there is the question how people handle putting masks on and off. And then, most common people will reuse masks instead of disposal (as in one time use in hospitals). If reuse, how masks are handled and sanitized matters.


All that is fine, but face masks do make an appreciable difference per all scientific literature dedicated to studying them.

Reusing masks is ok if you can disinfect them and if that's not possible, have the sense to discard them (properly) after a certain number of uses.

Even a washable two layer cloth mask helps in reducing virus sized particles from getting to you, by around 70%.

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Re: Wuhan Coronavirus Resource Thread

Postby Karan M » 05 May 2020 05:17

Zynda wrote:
srai wrote:^^^(Face shield is probably better.)

In India, any kind of PPE sale on e-commerce site is banned. So PPEs like face shields or even safety goggles are currently not available or not deliverable on Amazon, Flipkart etc.

I realize that PPEs first priority is for healthcare workers but when we are at a stage where we are coming out of lock down, I'd hoped that GoI would have made some of the PPEs, which could help in slowing down or preventing transmission, available to the public. Anyways, I will try inquiring at a couple of local pharmacies about availability of shields and/or goggles.

Surprisingly, safety goggles are available on Amazon US website. Read reviews where even nurses and other healthcare workers are buying these goggles on their own for daily use while treating Covid patients.

WHO has decent guidelines with animations & illustrations on how to wear & remove masks.


Local pharmacies in most cities are now carrying masks and sanitizers. Venus masks (N95) based on DRDO tech for instance are available, as are surgical masks.

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Re: Wuhan Coronavirus Resource Thread

Postby vijayk » 05 May 2020 06:44

Karan M wrote:
Local pharmacies in most cities are now carrying masks and sanitizers. Venus masks (N95) based on DRDO tech for instance are available, as are surgical masks.


can we order them in India?

https://www.business-standard.com/artic ... 206_1.html
A body suit developed by India's premier research and development organisation DRDO can protect doctors and other health workers attending on Covid-19 patients.

The Defence Research and Development Organisation (DRDO) said the body suit can shield doctors, medical staff, sanitation workers and others.


According to a DRDO statement, the body suit developed earlier for medical and paramedical staff to manage and evacuate the causalities in the event of radiological emergencies has now been converted into a full body suit to stop contamination.

"The suit is washable and has passed the ASTM International standards. The suit is widely tested by DRDO and other agencies and found suitable for the cause," it said.

Each suit costs Rs 7,000. Frontier Protective Wear Pvt Ltd, Kolkata and Medikit Pvt Ltd, Mumbai are producing 10,000 suits per day.

The body suit is one of the four instruments developed by the DRDO and ready to be deployed in 'War against Corona'.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 05 May 2020 10:57

4000 new cases in India today. Lock down is only being lifted now. The results of liquor crowding will be seen soon. And then there is the whole month of ramzan. The temperature and BCG theory will be fully tested soon in India. I think the ramzan effect is beginning to show.

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Re: Wuhan Coronavirus Resource Thread

Postby hanumadu » 05 May 2020 11:43

Image

Image

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Re: Wuhan Coronavirus Resource Thread

Postby vera_k » 05 May 2020 11:59

More malaria-like symptoms -

For some recovering COVID-19 patients, weeks of illness, uncertainty

Kate Porter has had a fever nearly every day for 50 days. She can't shake the extreme exhaustion that hit when she became infected with the coronavirus nearly two months ago.

After an initial positive COVID-19 test, Porter has since tested negative for the virus, yet symptoms persist.

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 05 May 2020 12:30

SARS-CoV-2 (COVID-19) Testing: Status Update:
A total of 1191946 samples have been tested as on 5 May 2020, 9 AM IST.


24 April 2020 - 541789 [ 41247 tested, 1667 positive (4.04%) ]
25 April 2020 - 579957 [ 38168 tested,1408 positive (3.68%) ]
26 April 2020 - 625309 [ 45352 tested, 1835 positive (4.04%) ]
27 April 2020 - 665819 [ 40510 tested, 1607 positive (3.96%) ]
28 April 2020 - 716733 [ 50914 tested, 1568 positive (3.07%) ]
29 April 2020 - 770764 [ 54031 tested, 1902 positive (3.52%) ]
30 April 2020 - 830201 [ 59437 tested, 1705 positive (2.86%) ]
1 May 2020 - 902654 [ 72453 tested, 1801 positive (2.48%) ]
2 May 2020 - 976363 [ 73709 tested, 2396 positive (3.25%) ]
3 May 2020 - 1046450 [ 70087 tested, 2564 positive (3.65%) ]
4 May 2020 - 1107233 [ 60783 tested, 2952 positive (4.85%) ]
5 May 2020 - 1191946 [ 84713 tested, 3656 positive (4.31% ) ]

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 05 May 2020 13:17

Even after respiratory symptoms fade, coronavirus victims face danger
Coronavirus victims are facing a new danger that may occur even after respiratory symptoms fade and infection from the virus clears.

Doctors are beginning to notice a troubling blood-clotting phenomenon, which is occurring more frequently in patients who have the virus. These clots are also being discovered in younger coronavirus patients and can result in sudden strokes or death.

“There’s something about this virus that’s exaggerated that to the nth degree,” said Mitchell Levy, chief of pulmonary critical care and sleep medicine at the Warren Albert School of Medicine, according to Bloomberg. “We’re seeing clotting in a way in this illness that we have not seen in the past.”

He added that blood clotting is “probably the most important thing that’s emerged over the last perhaps month or two."

Clots may form and damage several types of organs in the body. They include the heart, liver, or in patients’ arterial catheters and filters that support failing kidneys.

However, blood clotting that appears in the lungs is thought to be the most severe in coronavirus patients. It can impede blood flow and impact infected patients who already have difficulty breathing due to the virus -- previously believed to be a typical respiratory disease.

Margaret Pisani, an associate professor of medicine at the Yale University School of Medicine says clots in the lungs are likely what’s causing coronavirus patients who may appear well to suddenly “fall off the ledge” and develop a blood-oxygen deficiency, the paper reported.

Doctors had previously attributed lung damage to pneumonia, but they are now looking at clotting as well.

Dr. Hooman Poor, a lung specialist at Mount Sinai Hospital in New York, noticed blood was not flowing well through the lungs of 14 patients on ventilators, which he determined was due to clotting.

"I feel like all these patients have blood clots in their lungs," Poor said last month, according to the Reuters.

A report in the New England Journal of Medicine last week found that five people between the age of 33 to 49 who had strokes, also tested positive for the coronavirus. They were all treated for large-vessel blockages.

On April 13, a study published by researchers in the Netherlands found that 31 percent of intensive-care unit coronavirus patients they observed had a complication associated with clotting. The study described the findings as "remarkably high."

The large arterial lung clots can also put an overwhelming strain on the heart, which may result in cardiac arrest. Clotting may also disrupt blood flow for coronavirus patients on ventilators, said Edwin van Beek, chair of clinical radiology at the University of Edinburgh’s Queen’s Medical Research Institute, according to Bloomberg.

“That’s quite frightening when you think of it because we didn’t know what we’re up against until we were in a later stage," Frank Rasulo, a physician in neurocritical care in Italy told the paper.

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Re: Wuhan Coronavirus Resource Thread

Postby sajo » 05 May 2020 16:22

3 new deaths including an 11-year-old child have been reported in Pune district today. Total active cases of Covid-19 stands at 2,132 with rise in death toll to 118: Health Official.

Sad to see that Pune fatalities continue unabated. Worldwide the death rate amongst children is nearly 0, we seem to have several already in Mumbai, Pune and Gujarat. With the mayhem following lifting of the lockdown, the next 15 days are going to be extremely critical.

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Re: Wuhan Coronavirus Resource Thread

Postby sajo » 05 May 2020 19:53

Any anecdotal evidence of the effectivity of Favipiravir from the good doctors here ? Has it shown any promise on anyone whether in India or the USA ? Is HCQ+Hiv Drugs still the go-to combination used here in India?

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Re: Wuhan Coronavirus Resource Thread

Postby chola » 05 May 2020 20:54

sajo wrote:3 new deaths including an 11-year-old child have been reported in Pune district today. Total active cases of Covid-19 stands at 2,132 with rise in death toll to 118: Health Official.

Sad to see that Pune fatalities continue unabated. Worldwide the death rate amongst children is nearly 0, we seem to have several already in Mumbai, Pune and Gujarat. With the mayhem following lifting of the lockdown, the next 15 days are going to be extremely critical.


It is sad and I expect we will see some rise in the next 15 days.

But India will never get to the disaster I am seeing here in Amreeka -- 1.2m cases and 70k+ dead. People just don't realize how well Modi had done with the exact same (dis)information that Trump got. And he had four times the population and 10 times less resources to work with.

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Re: Wuhan Coronavirus Resource Thread

Postby Primus » 05 May 2020 21:20

sajo wrote:Any anecdotal evidence of the effectivity of Favipiravir from the good doctors here ? Has it shown any promise on anyone whether in India or the USA ? Is HCQ+Hiv Drugs still the go-to combination used here in India?


Not being used in our area, as far as I know, it is only remdesivir now, even HCQ has been stopped, Azithro was stopped several weeks ago. Plasma transfusions from recovered patients being used as part of a trial, IL6 inhibitors, and GMCSF inhibitors too being used in special cases. Famotidine has suddenly become popular in one of the hospital systems here, as a result, many patients using it for heartburn can no longer find it.


Added hashtag #RemediesCOVID19
Last edited by ramana on 06 May 2020 08:03, edited 1 time in total.
Reason: Edited by ramana.

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 06 May 2020 00:53


Nevada nurse who came to NYC to work on the coronavirus frontlines claims minority patients are being murdered by negligent doctors misplacing ventilator tubes and giving unnecessary defibrillation, but 'nobody cares'

By LAURA COLLINS, CHIEF INVESTIGATIVE REPORTER FOR DAILYMAIL.COM

PUBLISHED: 22:57 BST, 5 May 2020 | UPDATED: 02:09 BST, 6 May 2020

A frontline nurse treating coronavirus in New York has claimed that patients are 'literally being murdered' by medical negligence and mismanagement every day, but that 'nobody cares because they're all minorities.'

Speaking out in despair 37-year-old Nicole Sirotek described work at the frontline as like 'going into the f***ing twilight zone,' and told of hospital units in such disarray that she was once assigned to care for a patient already in a body bag.

She said, 'They're not dying of COVID. Yes people are going to die of COVID, I know this, I'm not like a new grad student. I am literally saying they're murdering these people.

'And nobody cares because they're all minorities and we're in the f***ing hood and that's not okay.'

According to Sirotek, 'I legitimately don't know what to do anymore. Even the advocacy groups don't give a s*** about these people. Like literally, Black Lives Don't Matter here.'

Sirotek made her whistleblowing allegations in an emotional video posted on YouTube. Her decision to go public was driven by despair as her attempts to advocate for her patients have all fallen on deaf ears.

She said, 'What I need is someone to help me save these people from being killed from gross negligence and medical mismanagement and no-one is listening to me.' [..]

But according to the nurse's emotional video hospitals are no longer swamped as they once were and there are plenty of nurses in the wards on which she has worked.

There is now, she said, 'no reason' for the deaths that she has witnessed other than incompetence, mismanagement and a seemingly reckless lack of care on the part of some hospital personnel.

Sirotek said, 'They're medically mismanaging these patients…Nobody is listening. They don't care. I'm literally coming here each day and watching them kill them.'

Speaking from a hospital breakroom between changing units she recalled a series of deaths that she had witnessed that were not only avoidable but in some cases actively brought about by medical intervention.

She told of one patient who died while waiting for an X-ray because her warning that the anesthesiologist had misplaced a ventilator tube was ignored. She said, 'Literally only one side of his chest is inflating. He dies.'

She described how a resident doctor defibrillated a patient with an already beating heart. She recalled, 'The resident starts doing chest compressions which is not what you do. I run to stop him. He f***ing defibrillates him and kills him. I was literally saying, ''Can you stop him he's going to kill that patient?'' And the director of nursing just shook his head and I turned around and he killed the dude.'

Among other horrific incidents she listed are a nurse who placed a feeding tube into a patient's lungs, a nurse who administered a lethal dose of short acting insulin when she confused it for long acting and another who fell asleep at her station while a patient's blood pressure dropped without notice causing permanent mental impairment.

She told of one patient who choked to death on his own blood when the anesthesiologist ruptured his esophagus trying to intubate him and another whose lungs were 'blown out' by a wrongly set ventilator. [..]

In a state of clear exhaustion, the nurse said, 'Guys they don't even know when people are dead. How many times have I told you they've assigned me a dead person?'

On one occasion she was assigned to care for a patient about whom she had expressed repeated concern the previous night. She said, 'They assigned him to me, and he was already in a body bag.'

In a desperate attempt to put the situation into some sort of context Sirotek said, 'I know this is a kind of extreme example but it's the only one I can come up with.

'It's like if we were in Nazi Germany and they were taking the Jews to a gas chamber and I'm the one saying, 'Hey that's not okay. This is wrong.' And then everyone tells me, 'Hang in there. You're doing a great job. You can't save everybody.'

The nurse accepted that some people will suffer organ failure and die and that not everybody can be saved but said, 'I'm pretty sure when you defibrillate someone with a heart rate of 40 and a stable rhythm that's murder.

'And I'm pretty sure when you put someone's PEEP (Positive End Expiratory Pressure on a ventilator) up to 25 and PEEP doesn't go past like 15 or 20 and you blow someone's lungs out and they die - that's murder.'
Last edited by anmol on 06 May 2020 12:18, edited 1 time in total.

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Re: Wuhan Coronavirus Resource Thread

Postby Rahul M » 06 May 2020 01:59

Edited.

Thanks Anmol ji.

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 06 May 2020 02:22

a more contagious mutant strain has been sweeping globe

More lethal mutant of nCV with a different spike protein on envelope has taken over the original strain in Eu & US, and matter needs immediate attention as antibody (plasma) treatment won’t work https://news.sky.com/story/coronavirus- ... s-11983554

Researchers at Los Alamos National Laboratory in the US detected 14 mutations in the COVID-19 virus spike proteins, one of which - known as Spike D614G - they said was of "urgent concern".

Their research paper suggests the mutated strain of coronavirus that has become dominant across the world was first indentified in Europe and is different to those which spread early on in the pandemic.

So urgent is the issue that the research paper describing their findings has been made available before being peer-reviewed

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Re: Wuhan Coronavirus Resource Thread

Postby sudarshan » 06 May 2020 03:18

IndraD wrote:a more contagious mutant strain has been sweeping globe

More lethal mutant of nCV with a different spike protein on envelope has taken over the original strain in Eu & US, and matter needs immediate attention as antibody (plasma) treatment won’t work https://news.sky.com/story/coronavirus- ... s-11983554

Researchers at Los Alamos National Laboratory in the US detected 14 mutations in the COVID-19 virus spike proteins, one of which - known as Spike D614G - they said was of "urgent concern".

Their research paper suggests the mutated strain of coronavirus that has become dominant across the world was first indentified in Europe and is different to those which spread early on in the pandemic.

So urgent is the issue that the research paper describing their findings has been made available before being peer-reviewed


Could somebody else read this article and confirm or negate these observations of mine?

1. Nowhere in the article does it say that this new mutation is more lethal (higher fatality rate)

2. The authors themselves say:
The researchers acknowledge they do not know how the mutations have changed these key features.

("key features" referring to characteristics of the spike protein, which the virus uses to pry host cells open)

3. The article says - this new mutated form has been seen to be dominant in US and Europe since March, and is out-competing the original strain(s) from Wuhan
(And somehow they imply that this means the new form is more contagious, and will even cause reinfections - they do not specify how)

4. So this new strain has already been in action for a month to two months, the peak of the epidemic

5. And the authors also bypassed the peer review process because "this is so urgent"

Maybe there are more details in the paper? The article makes vague threats, doesn't say anything about "increased lethality," speculates a lot about higher transmissibility, warns that antibodies are going to be ineffective because the key feature of the virus has changed (while also saying - "we admit that we don't know how it has changed"), all this when the strain has already been doing its work for a month or two, which is basically two-thirds of the duration of this current pandemic in most of the world.

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Re: Wuhan Coronavirus Resource Thread

Postby ramana » 06 May 2020 08:02

Primus, Can I request you to post information on remedies that work and have been discarded?

Use hashtag #RemediesCOVID19

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Re: Wuhan Coronavirus Resource Thread

Postby Zynda » 06 May 2020 10:19

One piece of good news...
Recovered patients who tested positive for COVID-19 likely not reinfected
Posting excerpts...
But the general consensus in the scientific community — with all the information available to date on the new coronavirus — is that people aren't being reinfected, but rather falsely testing positive, Reiss said.


But reinfection at some point is a theoretical possibility. "We don't know what's going to happen a year from now, nobody has that kind of crystal ball," Reiss said.


Reassuringly, the virus is currently undergoing very small genetic changes that are "too tiny" to evade the immune systems of people who have already been infected. The genetic changes would have to be substantial enough that a person's existing antibodies to SARS-CoV-2 would no longer work against a new strain. So far, that seems unlikely.

"If this virus remains as it is [with] really tiny changes … then it's highly unlikely" that a person would be reinfected next year, Reiss added.

In the best-case scenario, which Reiss thinks is likely, the virus will behave like the virus that causes chickenpox, "imprinting" on the host immune memory. Then, even if antibody levels drop over time, people will retain a population of memory cells that can rapidly boost production of more antibodies if they are exposed to the virus again, Reiss said. Of course, this is still an "assumption," and it will be some time before we can fully understand the strength of the army the immune system creates against this virus — and whether that army's protection is long-lasting.

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Re: Wuhan Coronavirus Resource Thread

Postby chola » 06 May 2020 10:44

Talk about hopeful. What South Korea did is incredible. They were the worst hit country outside Cheen with their own version of Tablighi Jamaat spreading the wuhan virus everywhere in February.

They recorded two just new cases yesterday. They even allowed their baseball season to start (though to no fans initially.)

https://www.businessinsider.in/international/news/south-korea-reports-only-two-new-covid-19-cases/articleshow/75567764.cms

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Re: Wuhan Coronavirus Resource Thread

Postby habal » 06 May 2020 11:22

there is no need to lockdown economy imho, making compulsory wearing of masks and preventing crowding and practicing certain safe protocols are enough to prevent spread of this virus.

& US is leading epic misdiagnosis of this pandemic under able leadership of dr. antony fauci.

as this NY doctor says present protocols on using ventilators are leading to worse results.

why are CDC etc persisting with these protocols then.
maybe innocent but then again maybe not.

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Re: Wuhan Coronavirus Resource Thread

Postby anmol » 06 May 2020 12:29

SARS-CoV-2 (COVID-19) Testing: Status Update:
A total of 1276781 samples have been tested as on 6 May 2020, 9 AM IST.


24 April 2020 - 541789 [ 41247 tested, 1667 positive (4.04%) ]
25 April 2020 - 579957 [ 38168 tested,1408 positive (3.68%) ]
26 April 2020 - 625309 [ 45352 tested, 1835 positive (4.04%) ]
27 April 2020 - 665819 [ 40510 tested, 1607 positive (3.96%) ]
28 April 2020 - 716733 [ 50914 tested, 1568 positive (3.07%) ]
29 April 2020 - 770764 [ 54031 tested, 1902 positive (3.52%) ]
30 April 2020 - 830201 [ 59437 tested, 1705 positive (2.86%) ]
1 May 2020 - 902654 [ 72453 tested, 1801 positive (2.48%) ]
2 May 2020 - 976363 [ 73709 tested, 2396 positive (3.25%) ]
3 May 2020 - 1046450 [ 70087 tested, 2564 positive (3.65%) ]
4 May 2020 - 1107233 [ 60783 tested, 2952 positive (4.85%) ]
5 May 2020 - 1191946 [ 84713 tested, 3656 positive (4.31%) ]
6 May 2020 - 1276781 [ 84835 tested, 2971 positive (3.50%) ]

Kati
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Re: Wuhan Coronavirus Resource Thread

Postby Kati » 06 May 2020 13:24

Researcher 'on verge of making very significant' coronavirus findings shot to death

A medical researcher said to be on the “verge of making very significant” coronavirus findings was found shot to death over the weekend in Pennsylvania, officials said.

Bing Liu, 37, a researcher for the University of Pittsburgh School of Medicine, was found dead Saturday inside a home in Ross Township, north of Pittsburgh, the Allegheny County Medical Examiner said.

Bing Liu. (University of Pittsburgh)
Bing Liu. (University of Pittsburgh)
He had been shot in the head and neck, the agency said.

An hour after Liu's body was discovered, a second person, Hao Gu, 46, was found dead inside a car less than a mile away, the agency said.

Ross Township Police Detective Sgt. Brian Kohlhepp told the Associated Press that the men “appeared to be connected beyond their proximity to each other.” A motive for the killings remained unknown, and the relationship between the men was also unclear.

Download the TODAY app for the latest coverage on the coronavirus outbreak.

Liu, who earned a PhD in computational science from the National University of Singapore, worked as a postdoctoral fellow at Carnegie Mellon University before becoming a research associate at the University of Pittsburgh School of Medicine.

In a statement, the University of Pittsburgh described him as an excellent mentor and prolific researcher who had co-authored more than 30 papers. His work focused on systems biology.

“Bing was on the verge of making very significant findings toward understanding the cellular mechanisms that underlie SARS-CoV-2 infection and the cellular basis of the following complications,” the school said. “We will make an effort to complete what he started in an effort to pay homage to his scientific excellence.”

https://www.yahoo.com/news/researcher-v ... 20409.html

DrRatnadip
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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 06 May 2020 14:55

- Situation in Mumbai and Pune is getting worse with each passing day.

- Almost all critical care beds available are full.. Even healthcare workers getting affected are finding it difficult to find beds.

- Many hospitals have stopped admitting mild symptomatic/asymptomatic patients.. If some pt is sent home and he detoriates then blame will fall on doctors only.. Indian people are well known to assault doctors.. This is cause of concern..

- Everything from steroids , ivermectin to toclizumab is being tried.. Hard to say what is working .. HCQ is definitely working as prophylaxis..

- I expect very high number of cases in coming 15 -20 days.. Govt is preparing for it.. Private doctors are being recruited.. Norms of Various govt health schemes seems to be relaxed and many private hospitals are being included .. This is to ensure maximum patients get treatment through schemes like PMJAY..

- This epidemic will last longer than initial expectations.. So we should be prepared for repeated lockdowns..

- A pt aquiring immunity after infection does not mean that he wont get reinfected.. It just means pt is likely to escape CLINICALLY SIGNIFICANT CONSEQUENCES (Pneumonia/ ARDS is case of covid) of infection.. It is opinion of many healthcare workers that disease is already significantly spread in general population.. One friend also mentioned noticable increase in number of braught dead pts in hospitals.. They are not screened for covid.. We dont have resources to screen every unexplained death..So I dont know if COVID has caused rise, if any, in deaths which are atributed to other cause like Cardiac arrest etc..

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Re: Wuhan Coronavirus Resource Thread

Postby nam » 06 May 2020 15:51

The fact that the top effected cities are seeing growth despite being 3-4 weeks in lockdown, tells us people were not taking the lockdown seriously.

We have run out of icu's even after being in lockdown, imagine the state if things were normal.

It is only in Tier 2 cities that people have taken it seriously.

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Re: Wuhan Coronavirus Resource Thread

Postby Bart S » 06 May 2020 17:15

nam wrote:The fact that the top effected cities are seeing growth despite being 3-4 weeks in lockdown, tells us people were not taking the lockdown seriously.

We have run out of icu's even after being in lockdown, imagine the state if things were normal.

It is only in Tier 2 cities that people have taken it seriously.


It's well known that many will not take lockdowns seriously, but it is not up to the people. The whole point of the lockdown is that authorities must strictly enforce it. So, it means that the govts messed up the lockdown, no point in blaming people at large for the same.

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Re: Wuhan Coronavirus Resource Thread

Postby Sachin » 06 May 2020 18:20

Bart S wrote:It's well known that many will not take lockdowns seriously, but it is not up to the people. The whole point of the lockdown is that authorities must strictly enforce it. So, it means that the govts messed up the lockdown, no point in blaming people at large for the same.

What are the areas in which the governments (both state & central) messed up? What was the better way to implement the lock down?

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 06 May 2020 18:28

DrRatnadip wrote:- A pt aquiring immunity after infection does not mean that he wont get reinfected.. It just means pt is likely to escape CLINICALLY SIGNIFICANT CONSEQUENCES (Pneumonia/ ARDS is case of covid) of infection.. It is opinion of many healthcare workers that disease is already significantly spread in general population.. One friend also mentioned noticable increase in number of braught dead pts in hospitals.. They are not screened for covid.. We dont have resources to screen every unexplained death..So I dont know if COVID has caused rise, if any, in deaths which are atributed to other cause like Cardiac arrest etc..

dear dr ratandeep
this may not be correct, we yet have to see a valid case report of a recovered patient of covid getting ill again. Soko scientists already have explained viral genetic material in blood was giving false positive tests which were assumed to be reinfection.
Yes there are reports of patients not recovering even after 50 days of contracting virus, they continue to have fever, myalgia, a colleague (intensivist) contracted nCV and is short of breath even after 6 weeks of recovery.
This virus triggers immune system, which can take time to go, can manifest in many ways. That doesn;t mean reinfection.
In fact some patients after recovery developed skin lesions (due to SARS2 induced vasculitis, similar to infective endocarditis triggering unnecessary investigations.

DrRatnadip
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Re: Wuhan Coronavirus Resource Thread

Postby DrRatnadip » 06 May 2020 18:37

IndraD wrote:
DrRatnadip wrote:- A pt aquiring immunity after infection does not mean that he wont get reinfected.. It just means pt is likely to escape CLINICALLY SIGNIFICANT CONSEQUENCES (Pneumonia/ ARDS is case of covid) of infection.. It is opinion of many healthcare workers that disease is already significantly spread in general population.. One friend also mentioned noticable increase in number of braught dead pts in hospitals.. They are not screened for covid.. We dont have resources to screen every unexplained death..So I dont know if COVID has caused rise, if any, in deaths which are atributed to other cause like Cardiac arrest etc..

dear dr ratandeep
this may not be correct, we yet have to see a valid case report of a recovered patient of covid getting ill again. Soko scientists already have explained viral genetic material in blood was giving false positive tests which were assumed to be reinfection.
Yes there are reports of patients not recovering even after 50 days of contracting virus, they continue to have fever, myalgia, a colleague (intensivist) contracted nCV and is short of breath even after 6 weeks of recovery.
This virus triggers immune system, which can take time to go, can manifest in many ways. That doesn;t mean reinfection.
In fact some patients after recovery developed skin lesions (due to SARS2 induced vasculitis, similar to infective endocarditis triggering unnecessary investigations.


Sir , I did not want to say that reinfection is happening.. I wanted to say even if it happens it is likely to mild and will mostly go unnoticed..

Larry Walker
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Re: Wuhan Coronavirus Resource Thread

Postby Larry Walker » 06 May 2020 18:47

nam wrote:It is only in Tier 2 cities that people have taken it seriously.


I think there is lack of appreciation of the problems of Mumbai here. Being how cramped and slummed it is, for a majority of households therenis only enough space for all members to come together for meal and then sleep side-by-side at night. There is literally no space in the dwelling if all members are there together. Now imagine this situation for last 40 days.

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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 06 May 2020 18:52

Patients acutely symptomatic for 2 months and more

Fever, fatigue, fear: For some recovering COVID-19 patients, weeks of illness, uncertainty https://www.nbcnews.com/health/health-n ... s-n1197806

IndraD
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Re: Wuhan Coronavirus Resource Thread

Postby IndraD » 06 May 2020 18:53

https://www.thenation.com/article/socie ... ent-fauci/

How Long Will It Take Until There’s a Vaccine? They told us a vaccine for AIDS might take two years to develop. That was in 1984, and we’re still waiting.
Vaccine may not be available soon and social distancing, mask will be the new normal.


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