Cain Marko wrote:nachiket wrote:
The sample size is a grand total of 100, out of which 50 were given a placebo, 45 given the drug and 5 refused consent and were excluded. This is an incredibly small sample size. Moreover according to the doctor who conducted the trial, any patient with any comorbidity was excluded, most were young and were asymptomatic or mildly symptomatic. Even the moderately symptomatic ones were excluded and there is no data available on how they were randomized. These results also have not been peer reviewed yet nor have they been published in a medical journal. How they can claim the drug is a covid cure based on this I don't know.
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What makes you say the sample size is inadequate? Size is often the function of the statistical test used. And a 50:50 split sample is by no means small depending upon the assumptions of the test. A power analysis will tell you that the size for a significant anova result can be much lower than 50 per group. The study design is more important, and from the information we have there is nothing wrong with a blind rct design.
Compare this with the initial French studies done on the effectiveness of hcq. These studies' design/sample sizes were poor compared to what has been done by pyt. But laughable as it was, the world went gaga over hcq including backing from profs in Stanford, media experts like Oz and numerous other bigwigs. Otoh in India, a study is conducted with far more rigor and much better design, but the drug and company are instantly parodied and spat upon by so called local experts.
I think disha is right. People are showing horrible house nigger tendencies. More white than the white man, Mr. UT has decided to ban the rather harmless ayurvedic concoction!
Sorry but had to say this. India has Salman Fanboys, Pawan Kalyan Fanboys, Baba Ram Raheem Fanboys, Asaram Bapuji Fanboys, Sonam Kapoor Fanboys, Homeopathy Rageboys and now Ramdev Rageboys.
Problem with these Fanboys/Rageboys is that you can put overwhelming facts/logic (what we consider facts, because Fanboys live in alternate universe) but the Fanboys are dedicated.
What Ramdev rageboys are not releasing is that with all the greatness of Ayurvedic medicine that we should all be proud, Ramdev baba decides to conduct trial in Allopathic setting with a principal investigator who has MBBS, MD degrees. Of course I will not ask the rage-boys on this because it will be branded as anti-Hindu.
Of course rage-boys will claim the study has greatest rigour ever in annals of clinical trials without knowing jackass about clinical protocols or what is double-blinded trials and why they are important.
Some rage-boys in WhatsApp were also offended when it was claimed that greatest medicine ever invented 'Coronil' was "Ashwagandha, Giloy, and Tulsi" which was already present in the cup-boards of the rage-boys.
In finality, it is better to wave white flag at these 'Asaram Bapuji' fan-boys, and agree that 'Asaram Bapuji is innocent, and is framed by Media, Courts, Police and also the Government'.
Let me also wave white flag at 'Ramdev Rageboys' and say "Modi is an anti-Hindu person who runs an evil government machinery that has stopped the greatest medicine ever invented called 'Coronil' that has proven to cure in vast majority of the patients the dreaded disease called Wuhan Virus". Ramdev Rageboys should continue to take this great medicine and in fact urge them to ask Baba to give it in suppository mode so that people on ventilators can also benefit from these tablets.